Results 91 to 100 of about 65,177 (296)
Treatment of pediatric epilepsy
Pediatric Investigation, EarlyView.Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li +8 more
wiley +1 more source
Are Excipients Inert? Phenytoin Pharmaceutical Investigations with New Incompatibility Insights
Journal of Pharmacy & Pharmaceutical Sciences, 2018 PURPOSE: The U.S. Pharmacopeia defines excipients as substances other than the active pharmaceutic ingredient (API) that are added in a drug delivery system in order to aid in the manufacturing process and enhance stability, bioavailability, safety ...
Daniela Amaral Silva +2 more
doaj +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen +6 more
wiley +1 more source
A Potentially Significant Interaction between Efavirenz and Phenytoin: A Case Report and Review of the Literature [PDF]
, 2005 Sarah Robertson +4 more
openalex +1 more source
Nanoemulsions for Skin Delivery of Essential Oils: A Systematic Review
Phytotherapy Research, EarlyView.ABSTRACT Essential oils (EOs) are recognized for their multiple health benefits. However, their high volatility, low stability, and limited water solubility limit their effective application. This systematic review aims to assess the use of nanoemulsions as delivery systems for the topical administration of EOs, highlighting their efficacy, safety, and
Thais Leticia Moreira da Silva +3 more
wiley +1 more source
The Effect of Sample Storage Temperature on the Phenytoin Level in Serum
Siriraj Medical Journal, 2015 Objective: To study the effect of temperature on phenytoin concentration in serum and to determine the sample were kept at 2-8°C and 35°C. Methods: Serum samples of patients, who had been treated with phenytoin.
Paiboon Tummarintra
doaj +2 more sources
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
British Journal of Pharmacology, EarlyView.Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background The activity of CYP2C9, an important drug metabolism enzyme, is subject to the impact of genetic polymorphism. The single nucleotide polymorphism *3 is significantly associated with the increased exposure of CYP2C9 substrates. In addition, metabolic enzyme inhibitors such as fluconazole may also increase the drug exposure of CYP2C9 ...
Shen Cheng +5 more
wiley +1 more source
Phenytoin‐induced gingival overgrowth
Acta Neurologica Scandinavica, 2012 Arya R, Gulati S. Phenytoin‐induced gingival overgrowth. Acta Neurol Scand: 2012: 125: 149–155. © 2011 John Wiley & Sons A/S.
Mitesh Karn, Ranjan Sah, S. Sapkota
semanticscholar +1 more source