Results 91 to 100 of about 92,765 (376)

Downbeat nystagmus: aetiology and comorbidity in 117 patients [PDF]

open access: yes, 2008
Objectives: Downbeat nystagmus (DBN) is the most common form of acquired involuntary ocular oscillation overriding fixation. According to previous studies, the cause of DBN is unsolved in up to 44% of cases.
Brandt, Thomas   +3 more
core   +1 more source

Topical Phenytoin Application in Grade I and II Diabetic Foot Ulcers: A Prospective Study.

open access: yesJournal of clinical and diagnostic research : JCDR, 2013
BACKGROUND India is fast becoming world diabetes capital. Diabetic foot infections are major problems among innumerable complications associated with diabetes.
V. Patil   +4 more
semanticscholar   +1 more source

Intralitter Variability Influences the Developmental Impact of Valproic Acid Exposure in CD‐1 Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Valproic acid (VPA) is an antiepileptic and mood‐stabilizing drug that causes teratogenic effects, including neural tube defects (NTDs), when taken during pregnancy. Although animal models are widely used to study VPA teratogenicity, most rely on litter means, which overlook variability within the litter.
Lauren T. L. Brown   +3 more
wiley   +1 more source

Phenytoin Concentrations in Biological Fluids of Traumatic Brain Injury Patients [PDF]

open access: yesImmunoAnalysis
Background: This study aims to determine and compare phenytoin concentrations in cerebrospinal fluid (CSF), serum, and urine. In addition, it strives to investigate their inter-correlations to provide insight into alternative monitoring methods. Methods:
Atefeh Razavi   +4 more
doaj   +1 more source

Era of direct acting anti-viral agents for the treatment of hepatitis C. [PDF]

open access: yes, 2018
Hepatitis C infection is universal and the most common indication of liver transplantation in the United States. The period of less effective interferon therapy with intolerable side effects has gone.
Ahmed, Monjur
core   +1 more source

Clinical considerations in transitioning patients with epilepsy from clonazepam to clobazam: a case series. [PDF]

open access: yes, 2014
IntroductionIn treating refractory epilepsy, many clinicians are interested in methods used to transition patients receiving clonazepam to clobazam to maintain or increase seizure control, improve tolerability of patients' overall drug therapy regimens ...
Chung, Steve   +4 more
core   +1 more source

Clinical Evaluation of Drug–Drug Interactions Between Bictegravir and Strong Inhibitors/Inducers of the CYP3A4, UGT1A1, or P‐gp Pathways

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract In addition to antiretroviral therapy (ART), people with HIV often take medications to treat comorbidities. It is therefore important to assess these medications for potential drug‐drug interactions, which may affect the safety and efficacy of ART. Three phase I studies were conducted in adult participants without HIV. The pharmacokinetics (PK)
Priyanka Arora   +4 more
wiley   +1 more source

Pharmacokinetic behavior of phenytoin in head trauma and cerebrovascular accident patients in an iranian population

open access: yesJournal of Research in Pharmacy Practice, 2017
Objective: Acute brain injury is one of the leading causes of morbidity and mortality worldwide. Phenytoin has been commonly used as an anticonvulsant agent for the treatment or prophylaxis of seizures following acute brain injury.
Shahnaz Alimardani   +6 more
doaj   +1 more source

Persistent vegetative state secondary to a motor vehicle accident [PDF]

open access: yes, 2012
The case presents a young girl who was involved in a road traffic accident. Despite being alive at present, her body cannot perform any basic functions since she is in a persistent vegetative state.
Abela, Franklin, Dimech, Anthony
core  

Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]

open access: yes, 2003
Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
core   +1 more source

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