Results 81 to 90 of about 45,385 (273)
Topical phenytoin for the treatment of neuropathic pain
, 2017 David J Kopsky,1 Jan M Keppel Hesselink2 1Institute for Neuropathic Pain, Amsterdam, 2Institute for Neuropathic Pain, Bosch en Duin, the Netherlands Abstract: We developed and tested a new putative analgesic cream, based on the anticonvulsant phenytoin ...
Kopsky DJ, Keppel Hesselink JM
core
Phenytoin Toxicity Due to Genetic Polymorphism
, 2009 Patients with traumatic brain injury commonly receive phenytoin for seizure prophylaxis. Due to the non-linear pharmacokinetics of phenytoin and narrow therapeutic window, phenytoin concentrations are monitored to ensure efficacy and prevent toxicity ...
McCluggage, Lauren +2 more
core +1 more source
Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms
Epilepsia, EarlyView.Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong +4 more
wiley +1 more source
Epilepsia, EarlyView.Long‐term efficacy and safety of adjunctive cenobamate in a multinational Asian population. Open‐label extension (OLE) efficacy population included all patients who had taken ≥1 dose of study drug and had any seizure data during the OLE maintenance phase.
Sang Kun Lee +20 more
wiley +1 more source
Optimization of nanoemulsion formulation containing phenytoin [PDF]
, 2017 Epilepsy is a Central Nervous System (CNS) disease caused by abnormal neuron signalling causing repeated seizures. CNS is protected by a barrier known as blood-brain barrier (BBB).
Yap, Mavin Chong Yang
core +1 more source
Phenytoin and gingival mucosa: A molecular investigation
International Journal of Immunopathology and Pharmacology, 2019 Several distinct classes of drugs, such as anticonvulsants, immunosuppressants, and calcium channel blockers, caused gingival overgrowth. One of the main drugs associated with the gingival overgrowth is the anti-epileptic such as phenytoin, which affects
Valentina Candotto +6 more
doaj +1 more source
Neonatal seizures: Advances in diagnosis and management
Epilepsia Open, EarlyView.Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz +2 more
wiley +1 more source
Plasmapheresis as an Adjunctive Therapy in Phenytoin Poisoning
Global Journal of Transfusion MedicinePhenytoin is frequently used as an anticonvulsant. Phenytoin has saturable metabolic kinetics in overdose circumstances, making therapy challenging. Because of its high protein binding property, the usual hemodialysis and hemoperfusion are not usually ...
Purshotam Paudel +3 more
doaj +1 more source
Phenytoin toxicity secondary to friend's advice!!
Annals of Indian Psychiatry, 2019 It is very common that antiepileptic prescription in substance induced seizure, however Phenytoin abuse is very rare. We report a case of 25 year old man with a known diagnosis of polysubstance abuse.
Jisha Myalil Lucca, Kishore M, Shruthi S
doaj +1 more source