Phenytoin Toxicity from Cocaine Adulteration [PDF]
The use of phenytoin (PHT) as a cocaine adulterant was reported decades ago;that practice is still current. Ironically PHT has also been used for the treatment of cocaine dependence.
Carlos J. Roldan
doaj +9 more sources
Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report [PDF]
We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder.
Ravi K. Thimmisetty +2 more
doaj +3 more sources
Phenytoin Toxicity with High Dose, Concomitant Ascorbic Acid Dosing
High dose ascorbic acid may increase risk of phenytoin toxicity. This case report demonstrates high phenytoin levels resulting in adverse drug reactions subsequent to dosing concomitantly with high dose vitamin C, or ascorbic acid (AA), as a precaution ...
Michael J. Schuh +2 more
doaj +2 more sources
Phenytoin Toxicity Treatment with Haemodialysis in Epilepsy due to Glioblastoma Multiforme: Case Report and Review of the Literature [PDF]
Phenytoin is one of the most commonly used anticonvulsants in the developing world, but lack of monitoring and concurrent medications can easily lead to toxicity.
Karishma Sharma +3 more
doaj +2 more sources
Myristicin and phenytoin toxicity in an infant. [PDF]
A developmentally normal infant presented with repeated episodes of afebrile status epilepticus following nutmeg ingestion. He had developed two episodes of afebrile status epilepticus and had received different treatments earlier, but the details of treatment were not available.
Sivathanu S +3 more
europepmc +4 more sources
Psychosis as Harbinger of Phenytoin Toxicity.
Psychosis with phenytoin use has earlier been reported only in the context of Vitamin B12 or folic acid deficiency. We report a rare case of phenytoin toxicity manifesting as psychosis in the absence of Vitamin deficiency. The importance of recognition of psychosis as a harbinger of phenytoin toxicity and implications for management are discussed.
Borasi M, Verma RP, Gupta SK.
europepmc +4 more sources
Drug Rescue for Paxlovid-Induced Tacrolimus Toxicity: A Pooled Analysis of Case Reports [PDF]
Rationale & Objective: Despite case reports suggesting the use of cytochrome P450 3A4 (CYP3A4) inducers for the treatment of Paxlovid-induced tacrolimus (TAC) toxicity, systematic validation is lacking.
Yafeng Huang +6 more
doaj +2 more sources
Therapeutic drug monitoring of antiepileptic drugs in the West Bank, Palestine: a 25-year retrospective cohort study from a multi-branch laboratory network [PDF]
Background Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is essential for optimizing seizure control while minimizing toxicity, particularly in resource-constrained settings.
Ibrahim Salhi, Bashar Karmi
doaj +2 more sources
Anti-NMDA receptor encephalitis with phenytoin toxicity: A diagnostic dilemma and management challenge [PDF]
Abhyuday Kumar +3 more
doaj +2 more sources

