Results 21 to 30 of about 621,544 (210)

Usual erratic phenomenon, dramatic outcome: a case report of phenytoin toxicity

Psychiatry and Clinical Psychopharmacology, 2021
Phenytoin is still one of the most commonly used antiepileptic drugs in clinical practice in many countries. It has a range of usual deleterious and erratic side effects, which have been reported previously including horizontal nystagmus, ataxia and ...
Madhusudan Singh Solanki, Kuldip Kumar
doaj   +1 more source

Unmasking phenytoin toxicity: a case of acute neuro-hepatic crisis [PDF]

Romanian Journal of Neurology
Phenytoin remains a widely prescribed antiepileptic, particularly in low- and middle-income countries, owing to its affordability. However, its narrow therapeutic index and unpredictable metabolism predispose patients to toxicity.
Manisha Nallani, Sarmini Varatharajan, Anthony Joseph Britto, Priyadarshini Varadaraj   +3 more
doaj   +1 more source

Death Due to Phenytoin Poisoning in an Intellectually Disabled Female Child: A Case Report

National Board of Examinations Journal of Medical Sciences, 2023
Phenytoin is a commonly used anticonvulsant, but its narrow therapeutic window can lead to toxicity, often due to medication errors or, in some cases, due to intentional overdose.
S.M. Krishna Sagar, Rakesh Miriyala, Sravani Yandava, T Mohit Kumar Moses, Narasimhulu Kuna, Kattamreddy Ananth Rupesh   +5 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Paxlovid with Caution: Novel Case of Paxlovid-Induced Tacrolimus Toxicity in a Cardiac Transplant Patients

European Journal of Case Reports in Internal Medicine, 2022
Tacrolimus is commonly used as a prophylactic against acute rejection in transplant patients. Tacrolimus toxicity has numerous presentations that have been well documented in the literature and can be induced by a wide variety of agents.
Aaisha Shah, Adeel Nasrullah, Muhammad Ali Butt, Meilin Young   +3 more
doaj   +1 more source

Phenytoin toxicity secondary to friend's advice!!

Annals of Indian Psychiatry, 2019
It is very common that antiepileptic prescription in substance induced seizure, however Phenytoin abuse is very rare. We report a case of 25 year old man with a known diagnosis of polysubstance abuse.
Jisha Myalil Lucca, Kishore M, Shruthi S
doaj   +1 more source

Genetic abnormality of cytochrome-P2C9*3 allele predisposes to epilepsy and phenytoin-induced adverse drug reactions: genotyping findings of cytochrome-alleles in the North Indian population

Future Journal of Pharmaceutical Sciences, 2022
Background This research aims to study the association of genetic polymorphism in genes coding for CYP2C9 and CYP2C19 in phenytoin-induced dose-related toxicity and to assess if the presence of allele CYP2C9*3 plays a role in phenytoin-induced ...
Vivek Kumar Garg, Supriya, Ritu Shree, Ajay Prakash, Aastha Takkar, Madhu Khullar, Biman Saikia, Bikash Medhi, Manish Modi   +8 more
doaj   +1 more source

Phenytoin-Induced Toxic Epidermal Necrolysis

Cureus, 2023
Toxic epidermal necrolysis (TEN) is a rare fatal mucocutaneous blistering disorder that can have varied underlying triggers. The percentage of body surface area (BSA) that is impacted by erosive blistering is what separates it from Steven Johnson syndrome (SJS), both of which have the same underlying pathogenesis and are thought to exist on a continuum
Tunuguntla, Mounika Nagarani, Chanti, Pranathi, Kesani, Tanishq, Yarapathineni, Kusuma, Kukkadapu, Prithvi   +4 more
openaire   +2 more sources

A case report of phenytoin-induced eosinophilic pneumonia

Respiratory Medicine Case Reports, 2019
Eosinophilic pneumonia comprises a rare and potentially serious group of lung diseases characterized by abnormal accumulation of eosinophils in the lungs. Many medications including the anticonvulsant phenytoin, have been implicated in the development of
Rhoda Annoh Gordon, Leann Silhan
doaj   +1 more source