Phenytoin Toxicity from Cocaine Adulteration [PDF]
Western Journal of Emergency Medicine, 2014 The use of phenytoin (PHT) as a cocaine adulterant was reported decades ago;that practice is still current. Ironically PHT has also been used for the treatment of cocaine dependence.
Carlos J. Roldan
doaj +7 more sources
Phenytoin Toxicity with High Dose, Concomitant Ascorbic Acid Dosing
INNOVATIONS in Pharmacy, 2022 High dose ascorbic acid may increase risk of phenytoin toxicity. This case report demonstrates high phenytoin levels resulting in adverse drug reactions subsequent to dosing concomitantly with high dose vitamin C, or ascorbic acid (AA), as a precaution ...
Michael J. Schuh +2 more
doaj +2 more sources
Phenytoin Toxicity Treatment with Haemodialysis in Epilepsy due to Glioblastoma Multiforme: Case Report and Review of the Literature [PDF]
Case Reports in Neurology, 2019 Phenytoin is one of the most commonly used anticonvulsants in the developing world, but lack of monitoring and concurrent medications can easily lead to toxicity.
Karishma Sharma +3 more
doaj +2 more sources
Oral Phenytoin Toxicity Causing Sinus Arrest: A Case Report [PDF]
Case Reports in Cardiology, 2014 We present a case of sinus node arrest leading to symptomatic junctional bradycardia from oral phenytoin toxicity, which is a rare presentation. Our patient had no prior cardiac history and was on phenytoin therapy for seizure disorder.
Ravi K. Thimmisetty +2 more
doaj +2 more sources
Psychosis as Harbinger of Phenytoin Toxicity.
Toxicol Int, 2015 Psychosis with phenytoin use has earlier been reported only in the context of Vitamin B12 or folic acid deficiency. We report a rare case of phenytoin toxicity manifesting as psychosis in the absence of Vitamin deficiency. The importance of recognition of psychosis as a harbinger of phenytoin toxicity and implications for management are discussed.
Borasi M, Verma RP, Gupta SK.
europepmc +4 more sources
Phenytoin-induced Ogilvie syndrome: A rare case report [PDF]
SAGE Open Medical Case ReportsPhenytoin is a widely prescribed antiepileptic drug that is associated with various adverse effects, but gastrointestinal manifestations are rare. Therapeutic drug monitoring is essential for ensuring safe and effective dosing by measuring the drug ...
Joel Sabu +2 more
doaj +2 more sources
Evaluation of neurotoxicity of drugs from morphological and electrophysiological endpoints using human iPSC-derived neural cell models [PDF]
Frontiers in Cellular and Infection MicrobiologyIntroductionGenome-edited human induced pluripotent stem cells (iPSCs) were first generated in 2007, and have been applied in pharmaceutical research, development, and clinical therapy as an in vitro platform for personalised phenotyping and drug ...
Zhe Qu +8 more
doaj +2 more sources
Anti-NMDA receptor encephalitis with phenytoin toxicity: A diagnostic dilemma and management challenge [PDF]
Indian Journal of Anaesthesia, 2021 Abhyuday Kumar +3 more
doaj +2 more sources
Investigation on the phenytoin sodium channel-blocker effect in PDT of MDA MB 231 breast cancer using a positively charged PS [PDF]
Scientific ReportsCancer therapy, due to the rising number of detected and reported cases, is one of the most important goals of scientists worldwide. Among these, there is a strong interest in using effective noninvasive protocols for cancer therapy.
HomaSadat Esfahani +2 more
doaj +2 more sources