Results 61 to 70 of about 45,385 (273)

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen, Amnah Omar Mahajna, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

<原著>Phenytoinの唾液成分に及ぼす影響について [PDF]

, 1988
P(論文)抗てんかん剤の長期服用は, 歯肉増殖を誘発したり, 体内の無機質, ビタミンD代謝に障害を及ぼすことが一般によく知られている。今回我々は, phenytoin(PHT)の唾液中成分に及ぼす影響について検討を行った。施設にて長期間PHTを服用している36人の重症心身障害児より, 血漿と混合唾液を採取した血漿の一部は超濾過し, ELISAにてPHT濃度を測定した。血中および混合唾液中の成分を36人の健康人と比較した結果, 唾液中のカルシウムと無機リンは, コントロール群に比較し ...
中村, 俊雄, IGARASHI, Seiji, NAKAMURA, Toshio, 渡部, 茂, 22368, WATANABE, Shigeru, 五十嵐, 清治, 22370, 35511, 35510, 市田, 篤郎, ICHIDA, Tokuro, 35509   +12 more
core  

Risk of hostility and aggression with perampanel monotherapy versus combination therapy in pediatric epilepsy: A Japanese post‐marketing database study using a nested case–control design

Epileptic Disorders, EarlyView.
Abstract Objective To compare the incidence of hostility‐ and aggression‐related adverse events in children with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures (FBTCS), receiving perampanel as monotherapy or in combination with other antiseizure medications (ASMs).
Yukitoshi Takahashi, Masato Takeuchi, Akiko Yoshimura, Kasumi Daidoji, Kazuhiro Matsutani, Mika Ishii   +5 more
wiley   +1 more source

Phenytoin Crystallization in Intravenous Fluids

, 1977
Free phenytoin crystallization in various commercially available intravenous solutions was investigated. Phenytoin determinations were completed at various time periods, before and after filtration, by spectrophotometric analysis.
Jerry L. Bauman, John K. Siepler, John Fitzloff   +2 more
core   +1 more source

Significant Inhibition of Protein Binding of Phenytoin [PDF]

, 2018
Aim: This research was aimed to assess the potential for inhibition of protein binding of phenytoin by tizoxanide in human plasma. Phenytoin was used because studies have proven to be a highly plasma protein-bound drug with a narrow therapeutic index and
Babayeva, Mariana, Alexander, Sheril, Mariana Babayeva, Flores, Jesse, Henrietta Ofuluozor, Sheril Alexander, Jesse Flores, Ofuluozor, Henrietta   +7 more
core   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Combination of Capecitabine and Phenytoin May Cause Phenytoin Intoxication: A Case Report

, 2015
Capecitabine is an oral antineoplastic agent, and phenytoin is an anticonvulsant drug with a narrow therapeutic index. Although the interaction between capecitabine and phenytoin is rare, it may be potentially fatal.
Tas, Faruk, CIFTCI, Serkan, Karabulut, Senem, Ciftci, Rumeysa   +3 more
core   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Phenytoin for neuroprotection [PDF]

The Lancet Neurology, 2016
Elena H, Martinez-Lapiscina, Magi, Andorra, Bernardo, Sanchez-Dalmau, Pablo, Villoslada   +3 more
openaire   +5 more sources