Results 91 to 100 of about 46,241 (267)

Phenytoin toxicity secondary to friend's advice!!

Annals of Indian Psychiatry, 2019
It is very common that antiepileptic prescription in substance induced seizure, however Phenytoin abuse is very rare. We report a case of 25 year old man with a known diagnosis of polysubstance abuse.
Jisha Myalil Lucca, Kishore M, Shruthi S
doaj   +1 more source

Bioavailability of phenytoin following oral administration of phenytoin-lipid conjugates to rats

, 1995
The bioavailability of phenytoin was evaluated in rats upon oral administration of phenytoin-lipid conjugates obtained by covalent binding of 3-hydroxymethylphenytoin to 1,3-dimyristoylglyceride via a succinidyl linkage, to 2-(1,3-dimyristoyl-2-glyceryl ...
Lambert, DM., Gerhard K E Scriba, Didier M Lambert, Poupaert, Jacques, Jacques H Poupaert, Scriba, GKE.   +5 more
core   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

DRUG INTERACTION INDUCED PHENYTOIN TOXICITY: A CASE REPORT [PDF]

, 2014
Phenytoin is a narrow therapeutic indexed antiepileptic drug. Many drugs competitively inhibit isoenzymes responsible for its metabolism when concurrently administered and increases the phenytoin plasma concentration leading to serious adverse effects ...
B.S, KESHAVA, P, Sarayu, ADEPU, RAMESH, M.S, Srikanth, Reddy, Soumya   +4 more
core   +1 more source

Phenytoin Concentrations in Biological Fluids of Traumatic Brain Injury Patients [PDF]

ImmunoAnalysis
Background: This study aims to determine and compare phenytoin concentrations in cerebrospinal fluid (CSF), serum, and urine. In addition, it strives to investigate their inter-correlations to provide insight into alternative monitoring methods. Methods:
Atefeh Razavi, Ali Meshkini, Mohammad Reza Afshar Mogaddam, Behrouz Seyfinejad, Maryam Khoubnasabjafari   +4 more
doaj   +1 more source

Dyskinesia Induced By Phenytoin.

, 2015
Phenytoin is an effective antiepileptic drug, although, it can be associated with many side effects, including dyskinesia. To describe the clinical characteristics of phenytoin induced dyskinesia.
Scotoni, A E, Montenegro, M A, Cendes, F
core  

Outcomes of patients with post‐stroke epilepsy: A scoping review on quality of life, readmissions, costs, seizure recurrence, and medication adherence

Epilepsia Open, EarlyView.
Abstract Objective Post‐stroke epilepsy (PSE) affects ≈10% of patients with stroke and is associated with adverse health and economic outcomes. We aimed to review published literature on health and economic outcomes for patients with PSE, with a specific focus on quality of life, hospital readmissions, healthcare costs, seizure recurrence, and ...
Nega Dagnew Baye, Emma Foster, Muideen T. Olaiya, Nigel C. Jones, Monique F. Kilkenny, Lachlan L. Dalli   +5 more
wiley   +1 more source

Response to Ng et al. on “Stimulus‐induced arousal with transient electroencephalographic improvement distinguishes nonictal from ictal generalized periodic discharges”

Epilepsia, EarlyView.
Philippe Gélisse, William O. Tatum, Arielle Crespel, Peter W. Kaplan   +3 more
wiley   +1 more source

Are Excipients Inert? Phenytoin Pharmaceutical Investigations with New Incompatibility Insights

Journal of Pharmacy & Pharmaceutical Sciences, 2018
PURPOSE: The U.S. Pharmacopeia defines excipients as substances other than the active pharmaceutic ingredient (API) that are added in a drug delivery system in order to aid in the manufacturing process and enhance stability, bioavailability, safety ...
Daniela Amaral Silva, Raimar Löbenberg, Neal Davies   +2 more
doaj   +1 more source

Pharmacokinetic drug interactions with phenytoin (part II)

, 1990
Part I of this article, which appeared in the previous issue of the Journal, covered the drug interactions affecting the pharmacokinetics of phenytoin.
Milne, R.W., Nation, R.L., Evans, A.M.
core   +1 more source