Photodynamic Evaluation of Synthesized Chlorin-Desthiobiotin Conjugate with Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells In Vitro and in Hydra Organisms In Vivo. [PDF]
Rutkowski BN, Isaac-Lam MF.
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PHOTOHEMOLYSIS OF GOAT ERYTHROCYTES BY PHEOPHORBIDE A
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Comparaison des méthodes d\u27extraction et de dosage pour le calcul des pigments chlorophylliens phytoplanctoniques : revue de la bibliographie récente [PDF]
Saint-Dizier, Michèle
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Sonodynamically induced antitumor effect of pheophorbide a
Cancer Letters, 1996The sonodynamically induced antitumor effect of pheophorbide a (Ph-a) was investigated. Both in vitro and in vivo effects on sarcoma 180 were tested in combination with ultrasound at 2 MHz. The rate of ultrasonically induced cell damage in air-saturated suspension was enhanced by twice with 80 microM Ph-a.
K, Umemura +3 more
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Photophysical studies of the pheophorbide a dimer
Journal of Photochemistry and Photobiology B: Biology, 2000This work reports on a monomer-dimer equilibrium state of pheophorbide a in solution. A methodology for controlling the equilibrium constant by use of temperature and solvent variation is described. The absorption spectrum of the dimer is calculated, using different prepared equilibria of monomer and dimer in solution.
I, Eichwurzel, H, Stiel, B, Röder
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Sodium pheophorbide a has photoactivated fungicidal activity against Pestalotiopsis neglecta
Pesticide Biochemistry and Physiology, 2019Sodium pheophorbide a (SPA) is a natural photosensitizer. To explore its antifungal activity and mechanism, we studied its inhibitory effects on spore germination and mycelial growth of Pestalotiopsis neglecta. We used sorbitol, 2-thiobarbituric acid (TBA) and electron microscopy to determine its effects on cell wall integrity, cell membrane lipid ...
Yang, Jing +6 more
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Derivatives of Pheophorbide‐a and Pheophorbide‐b from Photocytotoxic Piper penangense Extract
Chemistry & Biodiversity, 2011AbstractIn our screening program for new photosensitizers from Malaysian biodiversity for photodynamic therapy (PDT) of cancer, MeOH extracts of ten terrestrial plants from Cameron Highlands in Pahang, Peninsular Malaysia, were tested. In a short‐term 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyl‐2H‐tetrazolium bromide (MTT) assay, 20 μg/ml each of these ...
Fadzly Adzhar, Kamarulzaman +5 more
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Abstract A series of ortho-, meta- and para-substituted zinc porphyrin-pheophorbide dyads were synthesized directly from methyl pheophorbide-a by trans-esterification of β-keto methyl ester with hydroxymethyl substituted porphyrins. Quantitative energy transfer occurred from the excited zinc porphyrin to the pheophorbide.
Satoshi Shinoda +4 more
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Photodynamic Imaging of a Rat Pancreatic Cancer with Pheophorbide a
Photochemistry and Photobiology, 1996ABSTRACTLaser‐induced fluorescence of pheophorbide a (Ph‐a) was used for in vitro photodynamic imaging (PDI) of a rat pancreatic acinar tumor. A 400 nm excitation induced a 470 nm autofluorescence and a 678 nm dye fluorescence in tumors and their surrounding pancreas 24 h after a 9 mg kg−1 body weight Ph‐a intravenous administration.
Keller, P. +8 more
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