Results 221 to 226 of about 8,290 (226)

PHGDH/SYK: a hub integrating anti-fungal immunity and serine metabolism

Cell Death & Differentiation
Immune cells modify their metabolic pathways in response to fungal infections. Nevertheless, the biochemical underpinnings need to be better understood. This study reports that fungal infection drives a switch from glycolysis to the serine synthesis pathway (SSP) and one-carbon metabolism by inducing the interaction of spleen tyrosine kinase (SYK) and ...
Xinyong Zhang, Dongdong Hu, Xiaoyan Sun, Yichun Gu, Yong Zhou, Chuanxin Su, Shi Liu, Caiyan Zhang, Guoping Lu, Qiwen Wu, Aidong Chen   +10 more
openaire   +2 more sources

Targeting PHGDH exerts anti-oncogenic effects in bladder cancer

European Urology Supplements, 2019
H. Yoshino, Y. Osako, M. Yonemori, S. Tatarano, H. Enokida, M. Nakagawa   +5 more
openaire   +1 more source

Targeting the PHGDH-mTOR Metabolic Axis in Osteosarcoma

2021
openaire   +1 more source

3-Phoshoglycerate Dehydrogenase Deficiency (PHGDH, 1q12)

2008
openaire   +1 more source

Control of PHGDH by NOD2.

openaire   +1 more source

Disulfiram radiosensitizes hypoxic human colorectal cancer through inhibition of PHGDH

2021
Van De Gucht, M., Dufait, I., Jiang, H., Corbet, C., De Mey, S., Wang, H., Vandenplas, H., Law, K. L., Gevaert, T., Feron, O., De Ridder, M.   +10 more
openaire   +1 more source