Results 61 to 70 of about 174,356,890 (260)

Fc‐Dependent Targeting of the GAS6–MERTK Axis With Monoclonal and Bispecific Antibodies Overcomes Drug Resistance Across EGFR Mutations in Exons 19, 20, and 21

open access: yesAdvanced Science, EarlyView.
EGFR mutations drive a substantial fraction of non‐small cell lung cancers (NSCLC) and are effectively targeted by tyrosine kinase inhibitors (TKIs), including osimertinib. However, resistance inevitably develops through secondary mutations and compensatory receptor activation, including the GAS6 receptor MERTK.
Suvendu Giri   +28 more
wiley   +1 more source

Revisiting philosophy of education

open access: yesTeoría de la Educación: Revista Interuniversitaria, 2010
This study starts from the way philosophy of education was conceived by Richard Peters, how it has been amended in succeeding discussions within the Anglo-Saxon context as well has been the object of postmodern criticisms.
Paul SMEYERS
doaj   +1 more source

EDU405 : Development of education in Malaysia: philosophy & policy / Faculty of Education [PDF]

open access: yes, 2023
This course will introduce students to development of education in Malaysia philosophy and policy factors which influence ...
UiTM, Faculty of Education
core  

In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He   +20 more
wiley   +1 more source

Classical philosophy: influence the education philosophy of age

open access: yesTeraputik: Jurnal Bimbingan dan Konseling, 2018
Education with philosophy has a close relationship because philosophy is a view of life that leads to the goal of education. According to Dewey, changes that occur in society must exist and inevitable because education is always changing.
Mudafiatun Isriyah, Blasius Boli Lasan
doaj   +1 more source

Reference Electrode‐Free Nitrate Sensing via Differential Temperature‐Modulated Potentiometry in Printed Symmetric SC‐ISEs

open access: yesAdvanced Electronic Materials, EarlyView.
This work proposes and validates a method for measuring nitrate concentration with printed, solid‐state ion‐selective electrodes that does not require a stable reference electrode. The approach uses brief, localized heating pulses to generate a concentration‐dependent voltage response that is drift‐resilient and log‐linear from 0.1 to 100 mm, while ...
Lucas Lahann   +2 more
wiley   +1 more source

Filozofia wychowania jako filozofia

open access: yesFilozofia Publiczna i Edukacja Demokratyczna, 2013
In the article the Author analyzes different ways of understanding and practicing the philosophy of education. This analysis leads to the conclusion that methodological status of philosophy of education is indefinite, and this is an important issue that ...
Paweł Walczak
doaj   +1 more source

The Recent Engagement between Analytic Philosophy and Heideggerian Thought: Metaphysics and Mind [PDF]

open access: yes, 2016
Martin Heidegger is a towering figure in the history of continental philosophy, but his work has recently been brought into productive engagement with analytic philosophy.
Casati, Filippo, Wheeler, Michael
core   +1 more source

How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang   +4 more
wiley   +1 more source

Young children's perspectives of time: New directions for co‐constructing understandings of quality in ECEC

open access: yesBritish Educational Research Journal, EarlyView., 2023
Abstract Children's relationship with time in preschools is an under‐researched area. Young children rarely know how to measure time using a clock, but their experiences of time may contribute to understanding children's well‐being and debates about quality in preschools.
Kristín Dýrfjörð   +3 more
wiley   +1 more source

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