Alkaline Phosphatase and Hypophosphatasia [PDF]
Calcified Tissue International, 2015 Hypophosphatasia (HPP) results from ALPL mutations leading to deficient activity of the tissue-non-specific alkaline phosphatase isozyme (TNAP) and thereby extracellular accumulation of inorganic pyrophosphate (PPi), a natural substrate of TNAP and potent inhibitor of mineralization.
Michael P. Whyte +2 more
openaire +5 more sources
The ‘activation’ of phosphatase [PDF]
Biochemical Journal, 1944 G. E. Delory, E. J. King
openalex +4 more sources
Estimation of Plasma Phosphatase by Determination of Hydrolysed Phenol with Amino-antipyrine [PDF]
Journal of Clinical Pathology, 1954 P R Kind, E. J. King
openalex +2 more sources
Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin
Journal of Extracellular Vesicles, 2021 As novel mediators of cell‐to‐cell signalling, small extracellular vesicles (sEVs) play a critical role in physiological and pathophysiological processes. To date, the molecular mechanisms that support sEV generation are incompletely understood.
Yuefei Zhang +11 more
doaj +1 more source
Surface transects for arsenic speciation, antimony speciation, and alkaline phosphatase activity from R/V Knorr cruise KN204-01 in the Subtropical North Atlantic Ocean in 2011 (U.S. GEOTRACES NAT project) [PDF]
, 2020 Dataset: GT11 - As AP Surface TransectsSurface transects for arsenic speciation, antimony speciation, and alkaline phosphatase activity. Data for the concentrations of the dissolved (
Cutter, Gregory
core +1 more source
PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate
Biomolecules, 2022 Loss PTEN function is one of the most common events driving aggressive prostate cancers and biochemically, PTEN is a lipid phosphatase which opposes the activation of the oncogenic PI3K-AKT signalling network.
Helen M. Wise +7 more
doaj +1 more source
Biomolecules, 2022 Protein tyrosine phosphatase receptor gamma (PTPRG) is known to interact with and regulate several tyrosine kinases, exerting a tumor suppressor role in several type of cancers.
Christian Boni +2 more
doaj +1 more source
Regulation of NLRP3 Inflammasome by Phosphorylation
Frontiers in Immunology, 2018 The cytosolic pattern recognition receptor (PRR) NOD-like receptor family, pyrin domain containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Nan Song, Nan Song, Tao Li, Tao Li
doaj +1 more source
Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair [PDF]
, 2012 Microcephaly with early-onset, intractable seizures and developmental delay (MCSZ) is a hereditary disease caused by mutations in polynucleotide kinase/phosphatase (PNKP), a DNA strand break repair protein with DNA 5'-kinase and DNA 3'-phosphatase ...
Alexandra K. Walker +41 more
core +1 more source
The Role of DmCatD, a Cathepsin D-Like Peptidase, and Acid Phosphatase in the Process of Follicular Atresia in Dipetalogaster maxima (Hemiptera: Reduviidae), a Vector of Chagas' Disease [PDF]
, 2015 In this work, we have investigated the involvement of DmCatD, a cathepsin D-like peptidase, and acid phosphatase in the process of follicular atresia of Dipetalogaster maxima, a hematophagous insect vector of Chagas' disease. For the studies, fat bodies,
Canavoso, Lilian Etelvina +3 more
core +3 more sources