Results 11 to 20 of about 1,202,348 (359)

Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin

open access: yesJournal of Extracellular Vesicles, 2021
As novel mediators of cell‐to‐cell signalling, small extracellular vesicles (sEVs) play a critical role in physiological and pathophysiological processes. To date, the molecular mechanisms that support sEV generation are incompletely understood.
Yuefei Zhang   +11 more
doaj   +1 more source

PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate

open access: yesBiomolecules, 2022
Loss PTEN function is one of the most common events driving aggressive prostate cancers and biochemically, PTEN is a lipid phosphatase which opposes the activation of the oncogenic PI3K-AKT signalling network.
Helen M. Wise   +7 more
doaj   +1 more source

A Comprehensive Review of Receptor-Type Tyrosine-Protein Phosphatase Gamma (PTPRG) Role in Health and Non-Neoplastic Disease

open access: yesBiomolecules, 2022
Protein tyrosine phosphatase receptor gamma (PTPRG) is known to interact with and regulate several tyrosine kinases, exerting a tumor suppressor role in several type of cancers.
Christian Boni   +2 more
doaj   +1 more source

Regulation of NLRP3 Inflammasome by Phosphorylation

open access: yesFrontiers in Immunology, 2018
The cytosolic pattern recognition receptor (PRR) NOD-like receptor family, pyrin domain containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Nan Song, Nan Song, Tao Li, Tao Li
doaj   +1 more source

Acid phosphatases [PDF]

open access: yesMolecular Pathology, 2002
Acid phosphatases (APs) are a family of enzymes that are widespread in nature, and can be found in many animal and plant species. Mystery surrounds the precise functional role of these molecular facilitators, despite much research. Yet, paradoxically, human APs have had considerable impact as tools of clinical investigation and intervention.
H, Bull   +4 more
openaire   +2 more sources

Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair [PDF]

open access: yes, 2012
Microcephaly with early-onset, intractable seizures and developmental delay (MCSZ) is a hereditary disease caused by mutations in polynucleotide kinase/phosphatase (PNKP), a DNA strand break repair protein with DNA 5'-kinase and DNA 3'-phosphatase ...
Alexandra K. Walker   +41 more
core   +1 more source

Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis-Supplemented Diet in Rats [PDF]

open access: yes, 2009
Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet.
Iweala, E. E. J., Obidoa, O.
core   +1 more source

Surface transects for arsenic speciation, antimony speciation, and alkaline phosphatase activity from R/V Knorr cruise KN204-01 in the Subtropical North Atlantic Ocean in 2011 (U.S. GEOTRACES NAT project) [PDF]

open access: yes, 2020
Dataset: GT11 - As AP Surface TransectsSurface transects for arsenic speciation, antimony speciation, and alkaline phosphatase activity. Data for the concentrations of the dissolved (
Cutter, Gregory
core   +1 more source

Enzymatic activity toward poly(L-lactic acid) implants [PDF]

open access: yes, 1990
Tissue reactions toward biodegradable poly(L-lactic acid) implants were monitored by studying the activity pattern of seven enzymes as a function of time: alkaline phosphatase, acid phosphatase, -naphthyl acetyl esterase, -glucuronidase, ATP-ase, NADH ...
Feijen, J.   +4 more
core   +4 more sources

Proper Delay of Phosphorus Application Promotes Wheat Growth and Nutrient Uptake under Low Phosphorus Condition

open access: yesAgriculture, 2023
It is widely known that root morphology has different response mechanisms at different phosphorus (P) levels. However, the effects of P application times on wheat (Triticum aestivum L.) root morphology and, therefore, on growth and nutrient uptake are ...
Huixuan Yi   +6 more
doaj   +1 more source

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