Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin
As novel mediators of cell‐to‐cell signalling, small extracellular vesicles (sEVs) play a critical role in physiological and pathophysiological processes. To date, the molecular mechanisms that support sEV generation are incompletely understood.
Yuefei Zhang +11 more
doaj +1 more source
PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate
Loss PTEN function is one of the most common events driving aggressive prostate cancers and biochemically, PTEN is a lipid phosphatase which opposes the activation of the oncogenic PI3K-AKT signalling network.
Helen M. Wise +7 more
doaj +1 more source
Protein tyrosine phosphatase receptor gamma (PTPRG) is known to interact with and regulate several tyrosine kinases, exerting a tumor suppressor role in several type of cancers.
Christian Boni +2 more
doaj +1 more source
Regulation of NLRP3 Inflammasome by Phosphorylation
The cytosolic pattern recognition receptor (PRR) NOD-like receptor family, pyrin domain containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Nan Song, Nan Song, Tao Li, Tao Li
doaj +1 more source
Acid phosphatases (APs) are a family of enzymes that are widespread in nature, and can be found in many animal and plant species. Mystery surrounds the precise functional role of these molecular facilitators, despite much research. Yet, paradoxically, human APs have had considerable impact as tools of clinical investigation and intervention.
H, Bull +4 more
openaire +2 more sources
Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair [PDF]
Microcephaly with early-onset, intractable seizures and developmental delay (MCSZ) is a hereditary disease caused by mutations in polynucleotide kinase/phosphatase (PNKP), a DNA strand break repair protein with DNA 5'-kinase and DNA 3'-phosphatase ...
Alexandra K. Walker +41 more
core +1 more source
Some Biochemical, Haematological and Histological Responses to a Long Term Consumption of Telfairia occidentalis-Supplemented Diet in Rats [PDF]
Some biochemical, haematological and histological responses were studied in rats undergoing a long term feeding with a Telfairia occidentalis-supplemented diet.
Iweala, E. E. J., Obidoa, O.
core +1 more source
Surface transects for arsenic speciation, antimony speciation, and alkaline phosphatase activity from R/V Knorr cruise KN204-01 in the Subtropical North Atlantic Ocean in 2011 (U.S. GEOTRACES NAT project) [PDF]
Dataset: GT11 - As AP Surface TransectsSurface transects for arsenic speciation, antimony speciation, and alkaline phosphatase activity. Data for the concentrations of the dissolved (
Cutter, Gregory
core +1 more source
Enzymatic activity toward poly(L-lactic acid) implants [PDF]
Tissue reactions toward biodegradable poly(L-lactic acid) implants were monitored by studying the activity pattern of seven enzymes as a function of time: alkaline phosphatase, acid phosphatase, -naphthyl acetyl esterase, -glucuronidase, ATP-ase, NADH ...
Feijen, J. +4 more
core +4 more sources
It is widely known that root morphology has different response mechanisms at different phosphorus (P) levels. However, the effects of P application times on wheat (Triticum aestivum L.) root morphology and, therefore, on growth and nutrient uptake are ...
Huixuan Yi +6 more
doaj +1 more source

