Results 101 to 110 of about 3,150,482 (310)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Phosphate Contaminant Detection in Water Through a Paper-based Microfluidic Device [PDF]
, 2017 This report describes a project aimed at developing a low-cost, portable, on-site, user-friendly system for detecting different concentrations of phosphate in drinking water.
Miura, Brandon, Wagner, Alex, Wu, Philip
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Analysis of Human Kidney Stones Using Advanced Characterization Techniques
CrystalsA comprehensive analysis of kidney stones is essential for the future treatment of patients. Almost all of the methods available for kidney stone analysis were used in this study.
Jelena Brdarić Kosanović +7 more
doaj +1 more source
Applying Hubbert Curves and Linearization to Rock Phosphate [PDF]
Rock phosphate is a critical, nonrenewable resource for which there is no known substitute in agriculture. Cordell, Drangert, and White (2009) use Hubbert methodology (1956) to estimate the peak--the year after which production will monotonically decline-
Cullen S. Hendrix
core
Optical band gap and ir spectra of glasses in the system [Nd2O3](r)-[CuO](35-x)-[P2O5](65) [PDF]
, 2006 The infra red and ultraviolet-visible spectroscopiy of neodymium copper phosphate glasses on the [Nd2O3](x)-[CuO](35-x)-[P2O5](65) system with ...
Budi, Agus Setyo, Sahar, Md. Rahim
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Scientific ReportsGuizhou is a mountainous region that faces numerous engineering challenges during the mining of thick inclined ore bodies, including complex geological conditions, limited monitoring systems, and insufficient on-site monitoring.
Xinxin Huang +5 more
doaj +1 more source
Occurrence, distribution and genetic diversity of soil Phosphate Solubilizing Bacteria in soils of different chemical characteristics in Kenya [PDF]
, 2010 Phosphorus (P) availability in many soils is limited by high fixation and precipitation reactions, rendering it inaccessible for plant uptake. The ability to convert insoluble forms of P to an accessible form is an important trait in plant growth ...
Herrmann, Laetitia +5 more
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