Results 131 to 140 of about 3,784,388 (393)

On the Phosphate Rock Beneficiation for the Production of Phosphoric Acid in Saudi Arabia

Journal of King Saud University: Engineering Sciences, 1992
The establishment of phosphate fertilizers and the phosphoric acid industries are expected in Saudi Arabia in the near future. This is an attempt to review the processes involved in the phosphate rock beneficiation.
T.F. Al-Fariss, H.O. Ozbelge, H.S. El-Shall   +2 more
doaj  

Acoustic emission characteristics and damage constitutive model of fractured sandstone under uniaxial compression

Scientific Reports
To investigate the statistical laws of acoustic emission energy (AEE) avalanche dynamics of sandstone under varying fracture lengths and dip angles, as well as to determine the relationship between acoustic emission (AE) parameters and damage variables ...
Qiang Liu, Chao Pan, Lin Yan, Xuguang Wang, Shujian Li, Juncai Cao   +5 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors*

Journal of Biological Chemistry, 2002
Immunosuppressant drugs such as cyclosporin have allowed widespread organ transplantation, but their utility remains limited by toxicities, and they are ineffective in chronic management of autoimmune diseases such as multiple sclerosis. In contrast, the
V. Brinkmann, Michael D. Davis, C. Heise, R. Albert, S. Cottens, R. Hof, C. Bruns, E. Prieschl, T. Baumruker, P. Hiestand, C. A. Foster, M. Zollinger, K. Lynch   +12 more
semanticscholar   +1 more source

Assessment of in situ immobilization of Lead (Pb) and Arsenic (As) in contaminated soils with phosphate and iron: solubility and bioaccessibility [PDF]

, 2010
The effect of in situ immobilization of lead (Pb) and arsenic (As) in soil with respectively phosphate and iron is well recognized. However, studies on combined Pb and As-contaminated soil are fewer, and assessment of the effectiveness of the ...
Cui, Y.S., Du, X., Riemsdijk, W.H., van, Weng, L.P.   +3 more
core   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Phosphate nutrition: improving low-phosphate tolerance in crops.

Annual Review of Plant Biology, 2014
Phosphorus is an essential nutrient that is required for all major developmental processes and reproduction in plants. It is also a major constituent of the fertilizers required to sustain high-yield agriculture.
D. López-Arredondo, M. A. Leyva-González, S. González-Morales, J. López‐Bucio, L. Herrera-Estrella   +4 more
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Intelligent prediction system for surface movement and deformation in the subsequent filling mining of inclined, thick, and large ore

Scientific Reports
Guizhou is a mountainous region that faces numerous engineering challenges during the mining of thick inclined ore bodies, including complex geological conditions, limited monitoring systems, and insufficient on-site monitoring.
Xinxin Huang, Chen Wang, Xuyu Li, Weichao Ouyang, Yujun Zuo, Shan Jiang   +5 more
doaj   +1 more source