Results 121 to 130 of about 917,897 (332)

Intact FGF23 predicts serum phosphate improvement after combined nicotinamide and phosphate binder treatment in hemodialysis patients. [PDF]

Clin Kidney J, 2023
Egli-Spichtig D, Hamid AK, Arroyo EMP, Ketteler M, Wiecek A, Rosenkranz AR, Pasch A, Lorenz H, Hellmann B, Karus M, Ammer R, Rubio-Aliaga I, Wagner CA.   +12 more
europepmc   +1 more source

Изучение термомеханических свойств модифицированных корундографитовых карбидкремнийсодержащих огнеупоров [PDF]

, 2008
Представлено результати вивчення зміни уявної щільності, відкритої пористості і межі міцності при стиску після термічної обробки розроблених Al₂O₃ – SiС – С-композитів, модифікованих введенням фосфатної добавки і комплексного антиоксиданту (Al + Si ...
Анголенко, Л. А., Семченко, Галина Дмитриевна, Сидоров, В. Н., Старолат, Елена Евгеньевна, Тищенко, С. В.   +4 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Effect of Tenapanor on Phosphate Binder Pill Burden in Hemodialysis Patients. [PDF]

Kidney Int Rep, 2021
Akizawa T, Sato Y, Ikejiri K, Kanda H, Fukagawa M.   +4 more
europepmc   +1 more source

A Magnesium Based Phosphate Binder Reduces Vascular Calcification without Affecting Bone in Chronic Renal Failure Rats

PLoS ONE, 2014
The alternative phosphate binder calcium acetate/magnesium carbonate (CaMg) effectively reduces hyperphosphatemia, the most important inducer of vascular calcification, in chronic renal failure (CRF).
E. Neven, Tineke M. De Schutter, G. Dams, Kristina Gundlach, Sonja Steppan, J. Büchel, J. Passlick–Deetjen, P. D'Haese, G. Behets   +8 more
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Effect of Sevelamer on Mineral and Lipid Abnormalities in Hemodialysis Patients

Saudi Journal of Kidney Diseases and Transplantation, 2008
We conducted a prospective study in hemodialysis patients to assess the safety and efficacy of sevelamer, a non-absorbable phosphate binding polymer free of calcium and aluminum, in lowering serum phosphorus, serum intact parathyroid hormone, and serum ...
Hamida Fethi, Fatma Lilia, Barbouch Samia, Kaaroud Hayet, Helal Imed, Hedri Hafedh, Abdallah Taieb, Maiz Hedi, Kheder Adel   +8 more
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Safety and Phosphate‐Binding Capacity of Oxylanthanum Carbonate in Healthy Volunteers

Clinical and Translational Science
Despite the widespread use of currently available serum phosphate management options, elevated serum phosphate is common in patients with end‐stage kidney disease on dialysis.
Pablo E. Pergola, Melanie S. Joy, Armando Garsd, Steve J. Hasal, Atul Khare, Guru Reddy, Pramod Gupta, William F. Finn   +7 more
doaj   +1 more source

Calcium-based phosphate binder use is associated with lower risk of osteoporosis in hemodialysis patients. [PDF]

Sci Rep, 2021
Hashimoto H, Shikuma S, Mandai S, Adachi S, Uchida S.   +4 more
europepmc   +1 more source