Results 131 to 140 of about 1,097,177 (350)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Characterization of GDP-mannose Pyrophosphorylase from Escherichia Coli O157:H7 EDL933 and Its Broad Substrate Specificity

, 2005
GDP-mannose pyrophosphorylase gene (ManC) of Escherichia coli (E. coli) O157 was cloned and expressed as a highly soluble protein in E. coli BL21 (DE3). The enzyme was subsequently purified using hydrophobic and ion exchange chromatographies. ManC showed
Hwang, Bum-Yeol, Kang, Young Bok (Abraham), Kim, Byung-Gee, Lee, Kwang-Won, Lee, Tek-Hyung, Park, Sung-Soo, Yang, Yung-Hun   +6 more
core  

Movement of Trace Elements During Residence in the Antarctic Ice: a Laboratory Simulation [PDF]

, 1991
Recent work has determined that differences in the trace element distribution between Antarctic eucrites and non-Antarctic eucrites may be due to weathering during residence in the ice, and samples that demonstrate trace element disturbances do not ...
Strait, Melissa M.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Efficient phosphate removal from water using ductile cast iron waste: a response surface methodology approach

Frontiers in Chemistry
Water scarcity is a critical issue worldwide. This study explores a novel method for addressing this issue by using ductile cast iron (DCI) solid waste as an adsorbent for phosphate ions, supporting the circular economy in water remediation.
Mai Hassan Roushdy, Nada Amr Elkhashab, Ahmed Ibrahim Osman, Dalia Amer Ali   +3 more
doaj   +1 more source

Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation

, 2020
Piming Zhao, Isaac D Liu, Jeffrey B. Hodgin, Peter I. Benke, Jeremy Selva, Federico Torta, Markus R. Wenk, James A. Endrizzi, O.R. West, Weixing Ou, Emily Tang, Denise Li‐Meng Goh, S K Tay, Hui‐Kim Yap, Alwin Hwai Liang Loh, Nicole Davis Weaver, Bonnie Sullivan, Austin Larson, Megan A. Cooper, Khalid Alhasan, Abdullah Alangari, Suha Salim, Evren Gümüş, Karin Chen, Martin Zenker, Friedhelm Hildebrandt, Julie D. Saba   +26 more
openalex   +2 more sources

First Record of a Tylosaurine Mosasaur from the Latest Cretaceous Phosphates of Morocco

, 2022
Trevor Rempert, Brennan P. Martens, Alexander P. M. Vinkeles Melchers   +2 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Glucose-6-Phosphate Dehydrogenase Deficiency: An Actionable Risk Factor for Patients with COVID-19?

, 2020
Brenda D. Jamerson, T. Ho Haryadi, Arline Bohannon   +2 more
openalex   +2 more sources