Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Initial and Residual Value of Phosphorus from Apatite Rock Phosphates and Superphosphates as Measured by 32p Dilution Technique [PDF]
, 1990 A pot trial using maize (Zea mays, L.) grown on an Ultisollabelled with 32p was carried out to evaluate the agronomic value of nine types of apatite rock phosphates and triple superphosphate.
Abdul Hamid, Sharifuddin +1 more
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Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Agronomic effectiveness of rock phosphates for corrective fertilization of an Oxisol from brazilian savanna cultivated with maize and common beans. [PDF]
, 2015 Due to the inherently low content and high degree of phosphorus fixation in the most part of Brazilian Savanna soils, Phosphorus fertilization is essential to attend crop demands. The fully acidulated phosphates are the main sources of Phosphorus used in
CARVALHO, M. da C. S. +3 more
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Calcium-binding capacity of organic and inorganic ortho- and polyphosphates [PDF]
The aim of this research was to determine the calcium-binding capacity of inorganic and organic ortho- and polyphosphates. This calcium-binding capacity can be used to influence the stability of, for example, casein micelles in dairy systems.
Hooijdonk, A.C.M., van +4 more
core +2 more sources
Application of Potential Phosphate‐Solubilizing Bacteria and Organic Acids on Phosphate Solubilization from Phosphate Rock in Aerobic Rice [PDF]
, 2013 Qurban Ali Panhwar +4 more
openalex +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
A Eutrophication Model of the White River Basin Above Beaver Reservoir in Northwest Arkansas [PDF]
, 1973 With national interest focused on man’s ever increasing degradation of the waters in this nation, it is clearly evident that an accurate assessment of all parameters influencing water quality needs to be made.
Gearhart, Robert A. +3 more
core +2 more sources
Mechanism of phosphate sensing and signaling revealed by rice SPX1-PHR2 complex structure [PDF]
, 2021 Jia Zhou +13 more
openalex +1 more source
FEBS Open Bio, EarlyView.IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source