Results 61 to 70 of about 253,540 (236)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Thermal stability of phosphate coatings on steel

open access: yesMetalurgija, 2015
The work was validated thermal stability of zinc, manganese and tri-cations phosphate coatings on steel, made from commercial phosphating bath type Pragofos.
P. Pokorny   +4 more
doaj  

Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein [PDF]

open access: yes, 1993
Cotransfection assays were used to show that the members of the GTP-binding protein Gq class of alpha subunits could activate phospholipase C (PLC) beta 2.
Katz, Arieh   +2 more
core  

Optimization of struvite precipitation in synthetic biologically treated swine wastewater - Determination of the optimal process parameters [PDF]

open access: yes, 2013
A sustainable way to recover phosphorus (P) in swine wastewater involves a preliminary step of P dissolution followed by the separation of particulate organic matter.
Biscans, Béatrice   +4 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Nutrients retention in a small subtropical wetland (México)

open access: yesJournal of Limnology, 2016
In tropical areas very few studies have analysed wetlands’ ability to control nutrients. We analysed the efficiency of the Pátzcuaro subtropical wetland in Mexico to retain nutrients (total phosphorus: TP; soluble reactive phosphorus: PO43-, nitrite: NO2-
Martha B. Rendón-López   +6 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Natural Chemical Composition of Commercial Fish Species: Characterisation of Pangasius, Wild and Farmed Turbot and Barramundi

open access: yesFoods, 2016
To comply with the relevant legal requirements and correct labelling, it is necessary for business operators and inspection authorities to know the natural characteristics of the raw material.
Monika Manthey-Karl   +3 more
doaj   +1 more source

Extension of the spin-1/2 frustrated square lattice model: the case of layered vanadium phosphates [PDF]

open access: yes, 2009
We study the influence of the spin lattice distortion on the properties of frustrated magnetic systems and consider the applicability of the spin-1/2 frustrated square lattice model to materials lacking tetragonal symmetry.
A. P. Ramirez   +6 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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