Results 61 to 70 of about 922,377 (368)

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Phosphates Adsorption from Water by Recycled Concrete / Adsorpce Fosforečnanů Z Vody Recyklovaným Betonem

open access: yesGeoScience Engineering, 2014
Recyklovaný beton se díky svým vlastnostem začal v posledních letech uplatňovat i ve vodním hospodářství především jako sorbent nebo reakční činidlo.
Buriánek Pavel   +2 more
doaj   +1 more source

First rare-earth phosphate aerogel: sol-gel synthesis of monolithic ceric hydrogen phosphate aerogel [PDF]

open access: yesJournal of Sol-Gel Science and Technology 85 574-584 (2018), 2018
Since the late 1960s, ceric hydrogen phosphates have attracted the attention of scientists due to remarkable ion exchange, sorption, proton-conduction and catalytic properties. In this work, through the application of various solvents, we, for the first time, have obtained monolithic aerogels based on ceric hydrogen phosphates with high porosity (~99%)
arxiv   +1 more source

Catalytic activation of glycosyl phosphates for stereoselective coupling reactions

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Despite their dominant role as electrophiles in biosynthetic pathways promoted by enzymes, organic phosphates are rarely employed in laboratory synthesis, because phosphates are generally very poor leaving groups.
Samuel M. Levi   +3 more
semanticscholar   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

METHODS FOR ASSESSMENT OF INTERNAL NUTRIENT LOAD OF WATER BODIES (A REVIEW)

open access: yesTransactions of the Karelian Research Centre of the Russian Academy of Sciences, 2019
Internal nutrient load of freshwater bodies is a key element in the study and modeling of the processes of eutrophication of lakes and storage reservoirs.
Yury Datsenko
doaj   +1 more source

The "Other" Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo-Inositol Chemistry).

open access: yesAngewandte Chemie, 2016
Cell signaling via inositol phosphates, in particular via the second messenger myo-inositol 1,4,5-trisphosphate, and phosphoinositides comprises a huge field of biology. Of the nine 1,2,3,4,5,6-cyclohexanehexol isomers, myo-inositol is pre-eminent, with "
Mark P Thomas, S. J. Mills, B. Potter
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Nutrients retention in a small subtropical wetland (México)

open access: yesJournal of Limnology, 2016
In tropical areas very few studies have analysed wetlands’ ability to control nutrients. We analysed the efficiency of the Pátzcuaro subtropical wetland in Mexico to retain nutrients (total phosphorus: TP; soluble reactive phosphorus: PO43-, nitrite: NO2-
Martha B. Rendón-López   +6 more
doaj   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

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