Results 101 to 110 of about 5,041,800 (310)

Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids

Cells, 2020
Fibrillarin is a highly conserved nucleolar methyltransferase responsible for ribosomal RNA methylation across evolution from Archaea to humans. It has been reported that fibrillarin is involved in the methylation of histone H2A in nucleoli and other ...
Francisco Guillen-Chable, Ulises Rodríguez Corona, Alejandro Pereira-Santana, Andrea Bayona, Luis Carlos Rodríguez-Zapata, Cecilia Aquino, Lenka Šebestová, Nicolas Vitale, Pavel Hozak, Enrique Castano   +9 more
doaj   +1 more source

An amphitropic cAMP-binding protein in yeast mitochondria [PDF]

, 1989
: We describe the first example of a mitochondrial protein with a covalently attached phos-phatidylinositol moiety acting as a membrane anchor. The protein can be metabolically labeled with both stearic acid and inositol.
Bandlow W., Baranska J., Blok M., Brugge J., Burn P., Burn P., Cascales S. C., Cobon G. S., Cobon G. S., Cornell R., Courtneidge S. A., Cross G. A. M., Dils R. R., Dygas A., Gillfillan A. M., Guarnieri M., Hixson C. S., Hostetler K. Y., Jelsema C. L., Kraft A. S., Lassing I., Lassing I., Low M. G., Megli F. M., Meyer R. K., Muller G., Muller G., Muller G., Muller G., Nishizuka Y., Pelech S. L., Radika R., Rodel G., Rotman A., Schmidt M. F. G., Sefton B. M., Sleight R., Terce F., Towbin H., Wirtz K. W. A., Wirtz K. W. A., Wojtczak L., Yaffe M., Zborowski J.   +43 more
core   +3 more sources

Integrating construction and spatial imaging of organoid for tumor metabolic heterogeneity and interactions

VIEW, EarlyView.
Enzymatically derived tissue debris (TD) is utilized to establish patient‐derived lung cancer tissue spheres (LCOs), which, in conjunction with mass spectrometry imaging, enable the investigation of tumor metabolic heterogeneity and maintenance of CSCs.
Ling Guo, Zhaohua Xia, Jiaxin Wang, Xiaoling Yu, Chuanyue Wu, Qian Luo, Chao Zhao   +6 more
wiley   +1 more source

Synthesis of all-cis-1,3-diacylcyclopentane-1,2,3-triol-2-phosphate via acyl group migration in a cyclic diglyceride analog.

Journal of Lipid Research, 1979
The acid-catalyzed isomerization of the diglyceride analog (1,2,3/0)-1,2-dipalmitoylcyclopentane-1,2,3-triol has been used to generate syn-syn-1,3-diacyl-cyclopentane-1,2,3-triol, a required intermediate in the synthesis of a symmetrical all-cis-1,2,3/0 ...
A J Hancock, M D Lister
doaj  

Suppression of planar cell polarity signaling and migration in glioblastoma by Nrdp1-mediated Dvl polyubiquitination. [PDF]

, 2017
The lethality of the aggressive brain tumor glioblastoma multiforme (GBM) results in part from its strong propensity to invade surrounding normal brain tissue. Although oncogenic drivers such as epidermal growth factor receptor activation and Phosphatase
Angelastro, JM, Carraway, KL, Cuevas, A, Fry, WHD, Hatakeyama, J, Printsev, I, Rowson-Hodel, A, Saldana, MJ, Sweeney, C, VanderVorst, K, Wald, JH   +10 more
core   +3 more sources

Phosphatidylethanol in post‐mortem blood: A comparative study of blood matrices and its stability at routine storage conditions

Journal of Forensic Sciences, EarlyView.
Abstract Determination of alcohol markers in post‐mortem cases can be useful to classify drinking habits and potential alcohol habituation prior to death. Phosphatidylethanol (PEth) is a direct alcohol marker and is already commonly used in a variety of contexts.
Jeremai Hose, Hilke Andresen‐Streichert, Mario Thevis, Markus A. Rothschild, Martin Juebner   +4 more
wiley   +1 more source

Cellular phosphatidic acid sensor, α-synuclein N-terminal domain, detects endogenous phosphatidic acid in macrophagic phagosomes and neuronal growth cones

Biochemistry and Biophysics Reports, 2020
Phosphatidic acid (PA) is the simplest phospholipid and is involved in the regulation of various cellular events. Recently, we developed a new PA sensor, the N-terminal region of α-synuclein (α-Syn-N).
Haruka Yamada, Fumi Hoshino, Qiang Lu, Fumio Sakane   +3 more
doaj  

Phosphatidic acid formation and signaling in plant cells [PDF]

The Ukrainian Biochemical Journal
This review conteins updated information on the structure, localization and regulation of phosphatidic acid (PA)-producing enzymes phospholipase D, phosphoinositide-specific and non-specific phospholipases C and diacylglycerol kinases is analyzed.
Y. S. Kolesnikov, S. V. Kretynin, V. S. Kravets, Y. K. Bukhonska   +3 more
doaj   +1 more source

Sarcopenia from mechanism to diagnosis and treatment in liver disease [PDF]

, 2016
Sarcopenia or loss of skeletal muscle mass is the major component of malnutrition and is a frequent complication in cirrhosis that adversely affects clinical outcomes.
Dasarathy, Srinivasan, MERLI, Manuela
core   +1 more source

Fatty Acids of Human Platelet Phosphatides.

Experimental Biology and Medicine, 1961
SummaryThe fatty acids of blood platelet phosphatides have ben studied by silicic acid, and gas-liquid chromatography. PEPS fractions contain primarily arachidonic, stearic and oleic acids. Lecithin-sphingomyelin eluates contain principally palmitic, stearic and oleic acids.
Harris L. Ullman, Harold S. Ballard, Aaron J. Marcus   +2 more
openaire   +3 more sources