Prostacyclin production in rat aortic smooth muscle cells: role of protein kinase C, phospholipase D and cyclooxygenase-2 expression [PDF]
Objective: The present study was designed to investigate the role of protein kinase C (PKC) and phospholipase D (PLD) in angiotensin II (AngII)- and phorbol ester (PMA)-induced cyclooxygenase-2 (COX-2) expression and prostacyclin (PGI2) production in rat
Dubouloz, Frédérique+3 more
core
Exosomes in Metabolic Diseases: From Molecular Mechanisms to Clinical Applications
We summarize recent progress in exosome biology and elucidate their roles in interorgan communication networks underlying metabolic pathogenesis. We also comprehensively examine the evolving application of exosomes in metabolic disease management, with a focus on critically evaluating preclinical and clinical advances in exosome‐mediated therapeutic ...
Yanting Wu+3 more
wiley +1 more source
Rat Adipose Tissue Phosphatidic Acid Phosphatase: Lack of Effect of Nucleotides on Cytosolic Enzyme Activity. [PDF]
Ayman Al‐Shurbaji+18 more
openalex +1 more source
ABSTRACT Listeria monocytogenes is a foodborne pathogen that poses significant challenges to food safety and public health due to its ability to adapt to harsh environments, particularly those found in food processing facilities. This review explores the global transcriptional responses of L.
Nagendran Rajalingam, Sam Van Haute
wiley +1 more source
PHOSPHATIDIC ACID PHOSPHOHYDROLASE AND PHOSPHOLIPIDS IN TRACHEAL AND AMNIOTIC FLUIDS DURING NORMAL OVINE PREGNANCY [PDF]
Charles R. Rosenfeld+3 more
openalex +1 more source
This review provides a systematic evaluation of stem cell clinical trials (n = 94) to treat neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease. It also explores the emerging fields of preclinical and clinical investigations of stem cell‐derived exosome‐based therapies ...
Sevim Isik+4 more
wiley +1 more source
Multiple testing procedures under confounding
While multiple testing procedures have been the focus of much statistical research, an important facet of the problem is how to deal with possible confounding. Procedures have been developed by authors in genetics and statistics.
Ghosh, Debashis
core +1 more source
Suppressive effect of T cell proliferation via the CD29 molecule. The CD29 mAb 1 "K20" decreases diacylglycerol and phosphatidic acid levels in activated T cells. [PDF]
Michel Ticchioni+5 more
openalex +1 more source
Summary Diatoms are a major phylum of microalgae, playing crucial ecological roles. They derive from secondary endosymbiosis, leading to a complex intracellular architecture. Their ability to store oil in lipid droplets (LDs) upon unfavourable conditions has raised interest for applications, in particular biofuels, yet Lipid Droplet (LD) biogenesis ...
Damien Le Moigne+20 more
wiley +1 more source
Phosphatidic acid activation of protein kinase C-ζ overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids [PDF]
Cristina Limatola+3 more
openalex +1 more source