Results 111 to 120 of about 5,041,800 (310)

GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid

Cell Proliferation, EarlyView.
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu, Xuehan Zhao, Ying Fang, Cong Wang, Yichang Tian, Wan Tu, Qiqian Wu, Long Yan, Xiaokui Yang   +8 more
wiley   +1 more source

Fat metabolism in higher plants: XIII. phosphatidic acid synthesis and diglyceride phosphokinase activity in mitochondria from peanut cotyledons*

Journal of Lipid Research, 1960
A phosphatidic acid is the major lipid to become labeled when Pi32 (inorganic orthophosphate labeled with P32), under conditions of oxidative phosphorylation, or ATP32 is fed to mito-choline and phosphatidylethanolamine in the mitochondria obtained a ...
Clive Bradbeer, P.K. Stumpf
doaj  

Phosphatidic acid, a versatile water-stress signal in roots

Frontiers in Plant Science, 2013
Adequate water supply is of utmost importance for growth and reproduction of plants. In order to cope with water deprivation, plants have to adapt their development and metabolism to ensure survival.
Fionn eMcLoughlin, Christa eTesterink
doaj   +1 more source

The CAMP-binding Ectoprotein from Saccharomyces cereuisiae Is Membrane-anchored by Glycosyl-Phosphatidylinositol [PDF]

, 1992
Saccharomyces cerevisiae contains an amphiphilic CAMP-binding glycoprotein at the outer face of the plasma membrane (M, = 54,000). It is converted to a hydrophilic form byt reatment withg lycosyl-phosphatidylinositol- specific phospholipases C and D ...
Bandlow, Wolfhard, Fiedler, Franz, Müller, Günter, Schubert, Karin   +3 more
core  

Methylation of the Gpat2 promoter regulates transient expression during mouse spermatogenesis [PDF]

, 2015
Spermatogenesis is a highly regulated process that involves both mitotic and meiotic divisions, as well as cellular differentiation to yield mature spermatozoa from undifferentiated germinal stem cells.
Cattaneo, Elizabeth Renee, Coleman, Rosalind A., Garcia Fabiani, Maria Belen, Gonzalez-Baró, Lacunza, Ezequiel, Montanaro, Mauro Aldo, Pellon Maison, Magali   +6 more
core   +2 more sources

A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid–liquid phase separation to promote oncogenic YAP signaling

Cell Research, 2021
Rui-hua Li, Tian Tian, Qiwei Ge, Xinyu He, Cheng Shi, Junhong Li, Zhen Zhang, Fangzhou Liu, L. Sang, Zuo-zhen Yang, Yazhou Liu, Yan Xiong, Qingfeng Yan, Xu Li, Huai-qiang Ju, Jian Liu, Liangjing Wang, J. Shao, Wenqi Wang, Tianhua Zhou, Aifu Lin   +20 more
semanticscholar   +1 more source

Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid

Journal of Biological Chemistry, 2017
mTOR, the mammalian target of rapamycin, integrates growth factor and nutrient signals to promote a transformation from catabolic to anabolic metabolism, cell growth, and cell cycle progression.
D. Menon, Darin Salloum, Elyssa Bernfeld, E. Gorodetsky, A. Akselrod, M. Frias, J. Sudderth, Pei-Hsuan Chen, R. Deberardinis, D. A. Foster   +9 more
semanticscholar   +1 more source

Toward molecular phenotyping of temporal lobe epilepsy by spatial omics

Epilepsia, EarlyView.
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen, Ronny Mohren, Micca Neusinger, Tobias A. Dancker, Michiel Vandenbosch, Jan Beckervordersandforth, Benjamin Balluff, Rianna P. Van der Hel, Olaf E. M. G. Schijns, Govert Hoogland, Kim Rijkers, Berta Cillero‐Pastor, ACE epilepsy surgery group, Gwendolyn de Bruyn, Albert Colon, Jim Dings, Marc Hendriks, Danny Hilkman, Christianne Hoeberigs, Jochem van der Pol, Lotte de Jong, Kim Rijkers, Sylvia Klinkenberg, Vivianne van Kranen–Mastenbroek, Jeske Nelissen, Pieter Kubben, Walter M. Palm, Rob P. W. Rouhl, Olaf Schijns, Ilse van Straaten, Simon Tousseyn, Marielle Vlooswijk, Louis Wagner, Dorien Weckhuysen   +33 more
wiley   +1 more source

Evaluation of the Use of Phosphatidic Acid in the Diet on Growth Performance and Breast Meat Yield in Broilers

Animals, 2018
The use of feed additives to improve feed conversion while increasing growth is the goal of any broiler nutrition program. Therefore, it is important to evaluate potential feed additives not only for increased performance, but also for any negative ...
Eric B. Sobotik, Jason T. Lee, Scott Hagerman, Gregory S. Archer   +3 more
doaj   +1 more source

Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease

Journal of Neuroinflammation, 2017
BackgroundMultiple sclerosis is a neuroinflammatory demyelinating and neurodegenerative disease of the central nervous system characterized by recurrent and progressive demyelination/remyelination cycles, neuroinflammation, oligodendrocyte loss ...
Shinji Yamamoto, Kota Yamashina, M. Ishikawa, M. Gotoh, Sosuke Yagishita, Kensuke Iwasa, K. Maruyama, K. Murakami‐Murofushi, Keisuke Yoshikawa   +8 more
semanticscholar   +1 more source