Results 131 to 140 of about 5,041,800 (310)

Studies of the membrane‐bound flavocytochrome MsrQ flavin mononucleotide (FMN)‐binding site reveal an unexpected ubiquinone cofactor

open access: yesThe FEBS Journal, EarlyView.
The membrane‐bound heme flavoprotein MsrQ is the specific electron donor for the periplasmic methionine sulfoxide reductase MsrP. Analysis of its flavin environment revealed that ubiquinone (UQ) is a cofactor for MsrQ. However, redox studies demonstrate that UQ cannot function as an electron donor for the MsrPQ system.
Philippe Carpentier   +9 more
wiley   +1 more source

Cytidine triphosphate:phosphatidic acid cytidyltransferase in Escherichia coli

open access: yesJournal of Lipid Research, 1968
An enzyme has been found in particulate fractions of Escherichia coli that catalyzes the incorporation of cytidine triphosphate (CTP) into lipid in the presence of exogenous phosphatidic acid and Mg++. The product has been identified enzymatically and by
James R. Carter, Jr.
doaj  

Astrocyte-derived phosphatidic acid promotes dendritic branching

open access: yesScientific Reports, 2016
Astrocytes play critical roles in neural circuit formation and function. Recent studies have revealed several secreted and contact-mediated signals from astrocytes which are essential for neurite outgrowth and synapse formation.
Yan-Bing Zhu   +8 more
semanticscholar   +1 more source

Reciprocal regulation between AtFH5‐labeled secretory vesicles and PI(4,5)P2 oscillation at the plasma membrane directs pollen germination

open access: yesJournal of Integrative Plant Biology, EarlyView.
In Arabidopsis, FORMIN HOMOLOGY PROTEIN 5‐labeled secretory vesicles and phosphatidylinositol 4,5‐bisphosphate (PI(4,5)P2) form a self‐reinforcing loop, where vesicles deliver the phosphatidylinositol 4‐phosphate 5‐kinase AtPIP5K4 to promote PI(4,5)P2 production, which in turn facilitates vesicle attachment to the plasma membrane, highlighting a novel ...
Yuwan Zhao   +6 more
wiley   +1 more source

Phosphatidic acid and lipid-sensing by mTOR [PDF]

open access: yesTrends in Endocrinology & Metabolism, 2013
Mammalian target of rapamycin (mTOR) has been implicated as a sensor of nutrient sufficiency for dividing cells and is activated by essential amino acids and glucose. However, cells also require lipids for membrane biosynthesis. A central metabolite in the synthesis of membrane phospholipids is phosphatidic acid (PA), which is required for the ...
openaire   +3 more sources

Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes

open access: yesMolecular Microbiology, EarlyView.
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Otmane Lamrabet   +6 more
wiley   +1 more source

New, partially hydrolyzable synthetic analogues of lecithin, phosphatidyl ethanolamine, and phosphatidic acid

open access: yesJournal of Lipid Research, 1966
The synthesis of two new synthetic analogues of lecithin, two of phosphatidyl ethanolamine (``cephalin''), and one new phosphatidic acid analogue is described.
Arthur F. Rosenthal
doaj  

Tracking Diacylglycerol and Phosphatidic Acid Pools in Budding Yeast

open access: yesLipid Insights, 2016
Phosphatidic acid (PA) and diacylglycerol (DAG) are key signaling molecules and important precursors for the biosynthesis of all glycerolipids found in eukaryotes.
Suriakarthiga Ganesan   +2 more
semanticscholar   +1 more source

Plant‐derived vesicle‐like nanoparticles in food crops: emerging insights into nutritional biofortification and biomedical applications

open access: yesPlant Biotechnology Journal, EarlyView.
Summary Food crops, as the cornerstone of human nutrition, not only provide essential macronutrients but also encompass a rich spectrum of bioactive compounds that promote health. Of particular significance are underutilized minor crops, which contain unique beneficial components with proven nutraceutical properties. These valuable bioactive components
Jie Wang, Zhaosheng Kong
wiley   +1 more source

Quantitative Analysis of Cellular Diacylglycerol Content

open access: yesBio-Protocol, 2014
Diacylglycerol (DAG) is a bioactive lipid with diverse biological roles. DAG transiently accumulates in a membrane upon receipt of an appropriate stimulus that activates phospholipase C to cleave phospholipids.
Fikadu Tafesse   +2 more
doaj   +1 more source

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