Results 11 to 20 of about 30,263 (277)

Designing New Natural-Mimetic Phosphatidic Acid: A Versatile and Innovative Synthetic Strategy for Glycerophospholipid Research. [PDF]

Angew Chem Int Ed Engl
We report the role of the fatty acyl chains in biological activities of phosphatidic acids (PA). Several PA probes having two different fatty acyl chains were synthesized through a multi‐steps synthesis and bearing various fluorophores or photo‐cross‐linkers (PCL).
Schlichter A, Wolf A, Ferrand T, Cocq A, Riachy L, Vertueux S, Beauvais B, Courvalet M, Henry PJ, Tanguy E, Gonzales L, Ferlet R, Laguerre F, Decraene C, Pellissier A, Sebban M, Sabot C, Jeandel L, Cianférani S, Strub JM, Bénard M, Flon V, Peulon-Agasse V, Cardinael P, Ory S, Gasman S, Renard PY, Montero-Hadjadje M, Vitale N, Balieu S.   +29 more
europepmc   +3 more sources

Quantitative lipidomics analysis of changes in egg yolk lipids during spray-drying and subsequent accelerated storage

Current Research in Food Science, 2023
Egg yolks are rich in lipids that are easily altered during processing and storage. In this study, a liquid chromatography-tandem mass spectrometry strategy was used for quantitative lipidomics analysis of egg yolk after spray-drying processing and ...
Wei Luo, Xialei Liu, Beibei Wang, Di Wu, Jinqiu Wang, Fang Geng   +5 more
doaj   +1 more source

Phosphatidic acid synthesis in bacteria [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2013
Membrane phospholipid synthesis is a vital facet of bacterial physiology. Although the spectrum of phospholipid headgroup structures produced by bacteria is large, the key precursor to all of these molecules is phosphatidic acid (PtdOH). Glycerol-3-phosphate derived from the glycolysis via glycerol-phosphate synthase is the universal source for the ...
Jiangwei Yao, Charles O. Rock
openaire   +3 more sources

Mitochondria: Signaling with phosphatidic acid [PDF]

The International Journal of Biochemistry & Cell Biology, 2012
Mitochondria, once viewed as functioning relatively autonomously in the cell, have increasingly been recognized to be involved in numerous signaling networks that impact on a wide range of cell biological processes. In addition to the many types of proteins that mediate these pathways, the importance of signaling functions regulated via lipids and ...
Chia-Ying Yang, Michael A. Frohman
openaire   +3 more sources

PHOSPHATIDIC ACID SYNTHESIS IN YEAST [PDF]

Biochemical Journal, 1965
1. The presence of palmitoyl-CoA-l-glycerol 1-phosphate palmitoyltransferase (EC2.3.1.15) has been demonstrated in a particulate fraction of baker's yeast. 2. The enzyme has been characterized, and its activity studied as a function of pH and concentration of substrates. 3. Inhibition by thiol poisons and protection by acyl-CoA have been used to obtain
F. Lynen, N. J. Kuhn
openaire   +3 more sources

Effects of ionization and counterion binding on the surface areas of phosphatidic acids in monolayers.

Journal of Lipid Research, 1979
At 24-26 degrees C, force-area isotherms show that unionized dipalmitoyl phosphatidic acid forms a solid-condensed film while unionized egg and dioleoyl phosphatidic acids form liquid-expanded films. Surface area is a characteristic feature of a specific
G S Patil, N J Dorman, D G Cornwell
doaj   +1 more source

Characterization of key triacylglycerol biosynthesis processes in rhodococci. [PDF]

, 2016
Oleaginous microorganisms have considerable potential for biofuel and commodity chemical production. Under nitrogen-limitation, Rhodococcus jostii RHA1 grown on benzoate, an analog of lignin depolymerization products, accumulated triacylglycerols (TAGs ...
Amara, Sawsan, Diaz-Salazar, Carlos, Eltis, Lindsay D, Liu, Jie, Otani, Hiroshi, Seghezzi, Nicolas   +5 more
core   +2 more sources

Putting the pH into phosphatidic acid signaling [PDF]

BMC Biology, 2011
Abstract: The lipid phosphatidic acid (PA) has important roles in cell signaling and metabolic regulation in all organisms. New evidence indicates that PA also has an unprecedented role as a pH biosensor, coupling changes in pH to intracellular signaling pathways. pH sensing is a property of the phosphomonoester headgroup of PA.
Shin, John J, Loewen, Christopher J
openaire   +5 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Apparent convergence (at 2-monoacylglycerol level) of phosphatidic acid and 2-monoacylglycerol pathways of synthesis of chylomicron triacylglycerols.

Journal of Lipid Research, 1991
Dietary fats are converted into chylomicron triacylglycerols via the 2-monoacylglycerol and phosphatidic acid pathways of acylglycerol formation. In view of the known positional and fatty acid specificity of the acyltransferases, the triacylglycerol ...
LY Yang, A Kuksis
doaj   +1 more source