Results 201 to 210 of about 6,852,406 (251)
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Phosphatidic Acid-Mediated Signaling
2013Phosphatidic acid (PA) is recognized as an important class of lipid messengers. The cellular PA levels are dynamic; PA is produced and metabolized by several enzymatic reactions, including different phospholipases, lipid kinases, and phosphatases. PA interacts with various proteins and the interactions may modulate enzyme catalytic activities and/or ...
Yu, Liu, Yuan, Su, Xuemin, Wang
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
1. The membrane-bound phosphatidate-dependent phosphatidic acid phosphatase activity of rat lung has been investigated in cytosol and microsomal fractions using as a substrate [32P]phosphatidate bound to heat inactivated rat liver microsomes. Both activities demonstrated broad pH optima with a maximum of 7.4--8 for the cytosol and a maximum of 6.5--7.5
P G, Casola, F, Possmayer
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1. The membrane-bound phosphatidate-dependent phosphatidic acid phosphatase activity of rat lung has been investigated in cytosol and microsomal fractions using as a substrate [32P]phosphatidate bound to heat inactivated rat liver microsomes. Both activities demonstrated broad pH optima with a maximum of 7.4--8 for the cytosol and a maximum of 6.5--7.5
P G, Casola, F, Possmayer
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Evidence for Phosphatidic Acid as the Sodium Carrier
Nature, 1959THE mechanism of active transport of ions is one of the basic problems of cell physiology. For example, most cells extrude sodium against a concentration gradient, and the system which brings this about has been termed the ‘sodium pump’. The biochemical mechanism of the ‘sodium pump’ has remained a mystery.
L E, HOKIN, M R, HOKIN
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Thyroid al Synthesis of Phosphatidic Acid
Endocrinology, 1968The enzymatic formation of phosphatidic acid from l-α-glycerophosphate and fatty acid was studied in cell free systems of calf and guinea pig thyroid. Phosphatidic acid formation was assayed by measuring the conversion of water-soluble l-α-glycerophosphate to the lipid which is extractable by organic solvents.
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Phosphatidic acid phosphatase in the erythrocyte membrane
Biochimica et Biophysica Acta, 1963A magnesium-dependent α-phosphatidic acid phosphatase is present in the erythrocyte membrane which is stimulated by sodium, and to a lesser extent by lithium, ammonium, potassium and rubidium. Cesium produces little or no stimulation. No magnesium-dependent, sodium-stimulated, activity was observed with β-phosphatidic acid or lysophosphatidic acid; but
L E, HOKIN, M R, HOKIN, D, MATHISON
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Genetically Encoded Probes for Phosphatidic Acid
2012In addition to forming bilayers to separate cellular compartments, lipids participate in vesicular trafficking and signal transduction. Among others, phosphatidic acid (PA) is emerging as an important signaling molecule. The spatiotemporal distribution of cellular PA appears to be tightly regulated by localized synthesis and a rapid metabolism ...
Kassas, Nawal +6 more
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Antibodies to liposomal phosphatidylserine and phosphatidic acid
Biochemistry and Cell Biology, 1990Polyclonal antisera to phosphatidylserine or phosphatidic acid were induced in rabbits by injecting liposomes containing phosphatidylserine or phosphatidic acid and lipid A. Adsorption of antisera with liposomes containing different phospholipids revealed that some degree of reactivity with one or more phospholipids other than the immunizing ...
B, Banerji, C R, Alving
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Phosphatidic acids and derivatives VI†: Phosphatidic acids derived from batyl alcohol
Recueil Des Travaux Chimiques Des Pays-Bas, 1956AbstractThe synthesis of a number of phosphatidic acids derived from batyl alcohol and of the two batyl alcohol phosphoric acids is described.Some properties of these substances are discussed.
L. J. Stegerhoek, P. E. Verkade
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On the phosphatidic acid of myelin
Journal of Neurochemistry, 1968A, Sheltawy, R M, Dawson
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Metabolism of Phosphatidic Acid
1983In the first edition of the Handbook of Neurochemistry, Rossiter and Strickland1 reviewed the metabolism of phosphatidic acid in relation to the overall metabolism of phosphoglycerides, and Hawthorne and Kai2 described the metabolic relationship between phosphatidic acid and phosphoinositides.
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