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Mucosal Protection by Phosphatidylcholine [PDF]

open access: yesDigestive Diseases, 2013
The colonic mucus serves a first barrier towards invasion of commensal bacteria in stools to prevent inflammation. One essential component of intestinal mucus is phosphatidylcholine (PC) which represents more than 90% of the phospholipids in mucus indicative for a selective transport of PC into this compartment. It is arranged in lamellar structures as
W. Stremmel   +6 more
semanticscholar   +5 more sources

Barbiturate Interaction with Phosphatidylcholine [PDF]

open access: greenProceedings of the National Academy of Sciences, 1972
A hydrogen-bonding interaction between phenobarbital or pentobarbital with phosphatidylcholine in chloroform is indicated by the effects of added phosphatidylcholine on the infrared and proton magnetic resonance spectra of these barbiturates. The nitrogenbound proton of the barbiturate and the orthophosphate moiety of the phosphatidylcholine molecule ...
Raymond Novak, T. J. Swift
openalex   +4 more sources

Phosphatidylcholine synthesis in yeast.

open access: hybridJournal of Lipid Research, 1988
The two pathways for the biosynthesis of phosphatidylcholine, by way of phosphocholine and by methylation of phosphatidylethanolamine, in wild-type yeast (Saccharomyces cerevisiae) and in the yeast mutant GL7 have been compared. The mutant requires for growth a sterol, unsaturated fatty acids, and methionine.
Jean Chin, Konrad E. Bloch
openalex   +4 more sources

Phosphatidylcholine-Derived Lipid Mediators: The Crosstalk Between Cancer Cells and Immune Cells

open access: yesFrontiers in Immunology, 2022
To become resistant, cancer cells need to activate and maintain molecular defense mechanisms that depend on an energy trade-off between resistance and essential functions.
R. F. Saito   +3 more
semanticscholar   +1 more source

High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance

open access: yesNature Communications, 2021
High-fat diet (HFD) decreases insulin sensitivity. How high-fat diet causes insulin resistance is largely unknown. Here, we show that lean mice become insulin resistant after being administered exosomes isolated from the feces of obese mice fed a HFD or ...
Anil Kumar   +21 more
semanticscholar   +1 more source

Miscibility of Sphingomyelins and Phosphatidylcholines in Unsaturated Phosphatidylcholine Bilayers [PDF]

open access: yesBiophysical Journal, 2015
Polyunsaturated phospholipids are common in biological membranes and affect the lateral structure of bilayers. We have examined how saturated sphingomyelin (SM; palmitoyl and stearoyl SM (PSM and SSM, respectively)) and phosphatidylcholine (PC; dipalmitoyl PC and 1-palmitoyl-2-stearoyl PC (DPPC and PSPC, respectively)) segregate laterally to form ...
Anders Kullberg   +2 more
openaire   +3 more sources

Digestion and Absorption of Milk Phospholipids in Newborns and Adults

open access: yesFrontiers in Nutrition, 2021
Milk polar lipids provide choline, ethanolamine, and polyunsaturated fatty acids, which are needed for the growth and plasticity of the tissues in a suckling child.
Åke Nilsson   +2 more
doaj   +1 more source

Efficacy of injections of phosphatidylcholine into fat deposits-a non-surgical alternative to liposuction in body-contouring

open access: yesIndian Journal of Plastic Surgery, 2005
Injecting phosphatidylcholine has been used in South America as a non-surgical treatment in body contouring. The objective of this study was to demonstrate the efficacy of injecting phosphatidylcholine in the reduction of localised fat deposits.
Karl G Heinrich
doaj   +3 more sources

Phosphatidylcholine content in soybean: Genetic variability and the effect of growing year

open access: yesNotulae Scientia Biologicae, 2022
Information on the genetic variability of phosphatidylcholine (PC) content in soybean (Glycine max L.) is scanty. In the present investigation, estimation of PC content in 408 soybean accessions from 15 countries revealed a range of 2.04-8.80 mg/g soy ...
Aseem K. ANSHU   +4 more
doaj   +1 more source

Hemolysis of Rat Erythrocytes by Replacement of the Natural Phosphatidylcholine by Various Phosphatidylcholines [PDF]

open access: yesEuropean Journal of Biochemistry, 1980
Vesicles of a variety of types of phosphatidylcholine have been shown to be suitable donors of phosphatidylcholine to intact rat erythrocytes in the presence of a specific phosphatidylcholine exchange protein. Coincident with the progression of phosphatidylcholine exchange is the onset of hemolysis, occurring at degrees of exchange characteristic for ...
Lange, L.G.   +3 more
openaire   +4 more sources

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