Results 31 to 40 of about 111,710 (302)

Cyclin-dependent kinase activity enhances phosphatidylcholine biosynthesis in Arabidopsis by repressing phosphatidic acid phosphohydrolase activity [PDF]

, 2017
Coordination of endomembrane biogenesis with cell cycle progression is considered to be important in maintaining cell function during growth and development. We previously showed that the disruption of PHOSPHATIDIC ACID PHOSPHOHYDROLASE (PAH) activity in
Eastmond, Peter J., Adams, N., Kurup, Smita, Craddock, Christian P., Bryant, Fiona M., Hussey, Patrick J., Adams, Nicolette, Kroon, Johan T.M., Craddock, C. P., Hussey, P. J., Kurup, S., Eastmond, P. J., Bryant, F. M., Kroon, J. T. M.   +13 more
core   +1 more source

Effect of phospholipids and bile acids on cholesterol nucleation time and vesicular/micellar cholesterol in gallbladder bile of patients with cholesterol stones [PDF]

, 1993
Supersaturation and rapid nucleation of cholesterol in bile are of key importance in the pathogenesis of cholesterol gallstones. While the effects of bile acids and phospholipids on cholesterol saturation of bile have been extensively studied, their ...
Paumgartner, Gustav, Lange, V., Jüngst, Dieter, Huber, P., Lang, Thomas   +4 more
core   +1 more source

The PQ-loop protein Any1 segregates Drs2 and Neo1 functions required for viability and plasma membrane phospholipid asymmetry

Journal of Lipid Research, 2019
Membrane asymmetry is a key organizational feature of the plasma membrane. Type IV P-type ATPases (P4-ATPases) are phospholipid flippases that establish membrane asymmetry by translocating phospholipids, such as phosphatidylserine (PS) and ...
Mehmet Takar, Yannan Huang, Todd R. Graham   +2 more
doaj   +1 more source

Use of immobilized phospholipase A1-catalyzed acidolysis for the production of structured phosphatidylcholine with an elevated conjugated linoleic acid content

Grasas y Aceites, 2012
Structured phosphatidylcholine (SPC) was successfully produced via immobilized phospholipase A1 (PLA1) – catalyzed acidolysis of phosphatidylcholine (PC) with conjugated linoleic acid (CLA).
R. Baeza-Jiménez, J. González-Rodríguez, In-H. Kim, H. S. García, C. Otero   +4 more
doaj   +1 more source

Astrocytes are mainly responsible for the polyunsaturated fatty acid enrichment in blood–brain barrier endothelial cells in vitro

Journal of Lipid Research, 1998
To determine the respective roles of endothelial cells from brain capillaries and astrocytes in the conversion of circulating 18:2n–6 and 18:3n–3 into 20:4n–6 and 22:6n–3, respectively, a coculture of the two cell types mimicking the in vivo blood–brain ...
N. Bernoud, L. Fenart, C. Bénistant, J.F. Pageaux, M.P. Dehouck, P. Molière, M. Lagarde, R. Cecchelli, J. Lecerf   +8 more
doaj   +1 more source

Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT[S]

Journal of Lipid Research, 2015
Mice that lack phosphatidylethanolamine N-methyltransferase (Pemt−/− mice) are protected from high-fat (HF) diet-induced obesity. HF-fed Pemt−/− mice show higher oxygen consumption and heat production, indicating that more energy might be utilized for ...
Xia Gao, Jelske N. van der Veen, Carlos Fernandez-Patron, Jean E. Vance, Dennis E. Vance, René L. Jacobs   +5 more
doaj   +1 more source

Development and Validation of a Simple Method to Quantify Contents of Phospholipids in Krill Oil by Fourier-Transform Infrared Spectroscopy

Foods, 2021
This study focuses on developing a quantification method for phosphatidylcholine (PC) and total phospholipid (PL) in krill oil using Fourier-transform infrared (FT-IR) spectroscopy.
Se-Eun Park, Hyo-Yeon Yu, Sangdoo Ahn
doaj   +1 more source

Phosphatidylcholine protects against the hepatotoxicity of acrylamide via maintaining metabolic homeostasis of glutathione and glycerophospholipid

Food Science and Human Wellness
Acrylamide is classified as a Class 2A carcinogen and mainly metabolized to produce hepatotoxicity. Phosphatidylcholine is thought to protect the liver from damage, but the protective role of phosphatidylcholine on acrylamide-exposed metabolic disorders ...
Yaoran Li, Wei Jia, Yiju Zhang, Yong Wu, Li Zhu, Jingjing Jiao, Yu Zhang   +6 more
doaj   +1 more source

Quantitation of cholesterol crystallization from supersaturated model bile1

Journal of Lipid Research, 2002
Cholesterol crystallization is an essential step in gallstone formation. Although spectrophotometry and nephelometry have been used for quantitation of crystallization, potential effects of crystal size and shape have not been evaluated.
Piero Portincasa, Niels G. Venneman, Antonio Moschetta, André van den Berg, Giuseppe Palasciano, Gerard P. vanBerge-Henegouwen, Karel J. van Erpecum   +6 more
doaj   +1 more source

Evidence for distinct behaviour of phosphatidylcholine and sphingomyelin at the low density lipoprotein surface

, 1997
This study demonstrates that the use of high field1H NMR spectroscopy permits individual detection of phosphatidylcholine and sphingomyelin molecules at the surface of native low density lipoprotein (LDL) particles.
Murphy, H.C., Barnard, M.L., Raoof, A., Bell, J.D., White, J.J., Burns, S.P., Ala-Korpela, M., Iles, R.A.   +7 more
core   +1 more source