Results 31 to 40 of about 149,942 (303)

Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle

open access: yesFrontiers in Physiology, 2022
In Duchenne muscular dystrophy (DMD), lack of dystrophin increases the permeability of myofiber plasma membranes to ions and larger macromolecules, disrupting calcium signaling and leading to progressive muscle wasting. Although the biological origin and
William J. Valentine   +15 more
doaj   +1 more source

How do nematodes transfer phosphorylcholine to carbohydrates? [PDF]

open access: yes, 2010
An unusual aspect of the biology of nematodes is the attachment of phosphorylcholine (PC) to carbohydrate. The attachment appears to play an important role in nematode development and, in some parasitic species, in immunomodulation.
Harnett, W., Houston, K.M., Rzepecka, J.
core   +1 more source

Untargeted Lipidomic Analysis to Broadly Characterize the Effects of Pathogenic and Non-Pathogenic Staphylococci on Mammalian Lipids [PDF]

open access: yes, 2018
Modification of the host lipidome via secreted enzymes is an integral, but often overlooked aspect of bacterial pathogenesis. In the current era of prevalent antibiotic resistance, knowledge regarding critical host pathogen lipid interactions has the ...
Baker, Paul RS   +5 more
core   +4 more sources

Mangiferin-Loaded Smart Gels for HSV-1 Treatment

open access: yesPharmaceutics, 2021
Infections due to HSV-1 affect many people all over the world. To counteract this pathology, usually characterized by perioral sores or by less frequent serious symptoms including keratitis, synthetic antiviral drugs are employed, such as acyclovir ...
Mariaconcetta Sicurella   +7 more
doaj   +1 more source

In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy [PDF]

open access: yes, 1988
To evaluate liposome formulations for use as intracellular sustained-release drug depots, we have compared the uptake and degradation in rat liver and spleen of liposomes of various compositions, containing as their bulk phospholipid an ether-linked ...
Baldeschwieler, John D.   +2 more
core   +1 more source

Intermolecular Hydrogen-Bond Interactions in DPPE and DMPC Phospholipid Membranes Revealed by Far-Infrared Spectroscopy

open access: yesApplied Sciences, 2021
The vibrational signature in the far-infrared region of two different phospholipids, phosphatidylcholine (PC) and phosphatidylethanolamine (PE), was investigated as a function of relative humidity from 0 to 75% in order to evaluate the effect of ...
Valeria Conti Nibali   +3 more
doaj   +1 more source

The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism

open access: yesBiomolecules, 2023
The in vivo roles of lysophospholipase, which cleaves a fatty acyl ester of lysophospholipid, remained unclear. Recently, we have unraveled a previously unrecognized physiological role of the lysophospholipase PNPLA7, a member of the Ca2+-independent ...
Sayaka Harada   +8 more
doaj   +1 more source

A convenient method for lecithin purification from fresh eggs

open access: yesQuímica Nova, 2008
The increasing demand for fatty acid-free lecithin required modifications in existing purification methods. In this technical note we describe a purification procedure with the following steps: a) homogenization and extraction of yolks obtained from ...
Flavio A. Maximiano   +5 more
doaj   +1 more source

Herbal choline as an alternative to choline chloride in the diet of nursery piglets

open access: yesPesquisa Agropecuária Brasileira, 2023
The objective of this work was to evaluate the replacement of choline chloride supplementation by herbal choline in the diet of nursery piglets. The experimental design was randomized complete blocks (initial weight and sex) with 80 piglets, in five ...
Letícia Lopes de Godoi   +4 more
doaj   +1 more source

The PQ-loop protein Any1 segregates Drs2 and Neo1 functions required for viability and plasma membrane phospholipid asymmetry

open access: yesJournal of Lipid Research, 2019
Membrane asymmetry is a key organizational feature of the plasma membrane. Type IV P-type ATPases (P4-ATPases) are phospholipid flippases that establish membrane asymmetry by translocating phospholipids, such as phosphatidylserine (PS) and ...
Mehmet Takar   +2 more
doaj   +1 more source

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