Results 51 to 60 of about 114,039 (255)

Influence of low-level laser radiation on the physico-chemical indicators of biomembranes

Біофізичний вісник
Background: The study of physical and molecular mechanisms of the influence of low-level laser radiation (LLLR) of a wide frequency range on biological objects allows to clarify the problem of laser photomodulation at the level of natural biological ...
Л. В. Січевська, Т. M. Овсяннікова, А. О. Коваленко, І. А. Забєліна, О. М. Левченко, О. В. Гурін, В. П. Берест   +6 more
doaj   +1 more source

Phosphatidylcholine participates in the interaction between macrophages and lymphocytes

, 2000
The role of phosphatidylcholine molecules as mediator for the control of lymphocyte proliferation by macrophages was investigated. Phosphatidylcholine added to the culture medium inhibited the concanavalin A-stimulated lymphocyte proliferation in a ...
Anita Nishiyama-Naruke, Rui Curi
core   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

In vitro mimicry of essential fatty acid deficiency in human endothelial cells by TNFα impact of ω-3 versus ω-6 fatty acids

Journal of Lipid Research, 2002
Severe endothelial abnormalities are a prominent feature in sepsis with cytokines such as tumor necrosis factor (TNF)α being implicated in the pathogenesis.
Konstantin Mayer, Reinhold Schmidt, Marion Muhly-Reinholz, Tina Bögeholz, Stephanie Gokorsch, Friedrich Grimminger, Werner Seeger   +6 more
doaj   +1 more source

Lipidomics Analysis Indicates Disturbed Hepatocellular Lipid Metabolism in Reynoutria multiflora-Induced Idiosyncratic Liver Injury

Frontiers in Pharmacology, 2020
The root of Reynoutria multiflora (Thunb.) Moldenke (syn.: Polygonum multiflorum Thunb., HSW) is a distinguished herb that has been popularly used in traditional Chinese medicine (TCM).
Xiaofang Wu, Yating Zhang, Jiaqi Qiu, Ya Xu, Jing Zhang, Jing Zhang, Juan Huang, Junqi Bai, Zhihai Huang, Zhihai Huang, Xiaohui Qiu, Xiaohui Qiu, Xiaohui Qiu, Xiaohui Qiu, Wen Xu, Wen Xu   +15 more
doaj   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

TEST ON THE MEMORY-ENHANCING EFFECT OF PHOSPHATIDYLCHOLINE IN HUMANS.

, 1981
TEST ON THE MEMORY-ENHANCING EFFECT OF PHOSPHATIDYLCHOLINE IN ...
CYNTHIA MAY. HARRIS (7961060)
core   +3 more sources

Isolation of disaturated phosphatidylcholine with osmium tetroxide

Journal of Lipid Research, 1976
A simple, rapid, inexpensive method for isolating disaturated phosphatidylcholine from adult rat lung has been devised. Total lipids are reacted with osmium tetroxide dissolved in carbon tetrachloride, and the disaturated phosphatidylcholine is isolated ...
R J Mason, J Nellenbogen, J A Clements
doaj   +1 more source

Clearance of surfactant phosphatidylcholine via the upper airways in rabbits

, 1988
A possible route of clearance of surfactant phosphatidylcholine from the lungs is via the airways. To quantify surfactant loss via this pathway, latex bags were surgically placed into the abdomens of adult rabbits such that secretions cleared via the ...
A. Jobe, J. Humme, A. Pettenazzo, S. Seidner, M. Ikegami   +4 more
core   +1 more source

Plaque‐Hepatic Targeting Nanotherapy Disrupts the PCSK9‐LOX‐1 Axis to Suppress oxLDL in Atherosclerosis

Advanced Science, EarlyView.
Self‑amplifying PCSK9–LOX‑1 feedback axis drives atherosclerotic progression by promoting oxLDL generation and endothelial uptake. A dual‑targeting nanoplatform (siPCSK9@PEAL NPs‑aL) is constructed to simultaneously silence hepatic PCSK9 for lipid lowering and block plaque LOX‑1 for anti‑inflammation.
Yi Duan, Yijie Qiu, Yan Zhu, Quan Wang, Jiangtao Lin, Yourong Duan, Qi Wang, Yi Dong   +7 more
wiley   +1 more source