The understanding of the penetration and clusterization of 1-alkanol in bilayer membrane: An open outlook based on atomistic molecular dynamics simulation [PDF]
arXiv1-alkanols are well known to have anesthetic and penetration properties, though the mode of operation remains enigmatic. We perform extensive atomistic molecular dynamics simulation to study the penetration of 1-alkanols of different chain lengths in the dioleoyl-phosphatidylcholine (DOPC) bilayer model membrane.
arxiv
Neurodegenerative and Neurodevelopmental Roles for Bulk Lipid Transporters VPS13A and BLTP2
Movement Disorders, EarlyView.Abstract Background Bridge‐like lipid transfer proteins (BLTPs) mediate bulk lipid transport at membrane contact sites. Mutations in BLTPs are linked to both early‐onset neurodevelopmental and later‐onset neurodegenerative diseases, including movement disorders.
Sarah D. Neuman +4 more
wiley +1 more source
Rate-limiting steps in the cytidine pathway for the synthesis of phosphatidylcholine and phosphatidylethanolamine [PDF]
, 1977 Juan P. Infante
openalex +1 more source
Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy
Movement Disorders, EarlyView.Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik +8 more
wiley +1 more source
Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light
Medicinal Research Reviews, EarlyView.ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva +5 more
wiley +1 more source
Regulation of Phosphatidylcholine Biosynthesis in Saccharomyces cerevisiae [PDF]
, 1971 Charles J. Waechter, Robert L. Lester
openalex +1 more source
Acetylcholinesterase Inhibition and Antioxidant Activity of DHA‐Disubstituted Phospholipids
Molecular Nutrition &Food Research, EarlyView.1,2‐Di‐DHA‐PC phospholipids in nutraceutical form may cross the blood‐brain barrier and inhibit acetylcholinesterase (AChE) activity, with an efficacy similar to galantamine. This suggests their potential as neuroprotective agents in the treatment of Alzheimer's disease.
Ernestina Garcia‐Quinto +4 more
wiley +1 more source
The metabolism of the phosphonium analogue of choline in cultured cells. A useful nuclear-magnetic-resonance probe for membrane phosphatidylcholine [PDF]
, 1976 Edith Sim, C. A. Pasternak
openalex +1 more source
Automated Data Processing Workflows for Non‐Expert Users of NMR Facilities
Magnetic Resonance in Chemistry, EarlyView.Modern NMR spectrometers are typically organized in centralized, ultrahigh‐field facilities with multiple instruments that benefit from shared infrastructure and expertise. The acquisition of NMR experiments goes hand in hand with the analysis of the resulting data.
Armin Afrough +2 more
wiley +1 more source