Lipid Subclasses Differentiate Insulin Resistance by Triglyceride-Glucose Index. [PDF]
Naja K+3 more
europepmc +1 more source
Role of phospholipase A2 in the stimulation of sponge cell proliferation by homologous lectin. [PDF]
Friese, K.+8 more
core +1 more source
Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison+3 more
wiley +1 more source
Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses. [PDF]
Ma Y, Wu F, Yu Z, Yang L.
europepmc +1 more source
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu+8 more
wiley +1 more source
Inverse Bicontinuous and Discontinuous Phases of Lipids, and Membrane Curvature. [PDF]
Seddon JM.
europepmc +1 more source
GLS1‐mediated glutaminolysis supports GSH synthesis in cancer cells. GLS1 KO increases ROS, downregulates GPX4, and upregulates GPX1, making cells more sensitive to ferroptosis. Combining GLS1 or GPX1 inhibitors with a GPX4 inhibitor synergistically suppresses cancer growth.
Changsen Bai+13 more
wiley +1 more source
Exploring The Causal Relationship Between Lipid Profiles and Colorectal Cancer Through Mendelian Randomization: A Multidimensional Plasma Lipid Composition Perspective. [PDF]
Wu H+8 more
europepmc +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen+9 more
wiley +1 more source