Results 41 to 50 of about 144,923 (365)

Enhancement of Aqueous Solubility and Dissolution of Celecoxib through Phosphatidylcholine-Based Dispersion Systems Solidified with Adsorbent Carriers

open access: yesPharmaceutics, 2018
This study aimed to design phosphatidylcholine (PC)-based solid dispersion (SD) systems for enhancing the apparent aqueous solubility and dissolution of celecoxib (CLC), a selective cyclooxygenase-2 inhibitor with a highly hydrophobic property.
Kanghee Jo   +6 more
doaj   +1 more source

Fatty Acid Production and Direct Acyl Transfer through Polar Lipids Control TAG Biosynthesis during Nitrogen Deprivation in the Halotolerant Alga Dunaliella tertiolecta

open access: yesMarine Drugs, 2021
The aims of this work were to evaluate the contribution of the free fatty acid (FA) pool to triacylglyceride (TAG) biosynthesis and to try to characterize the mechanism by which FA are assimilated into TAG in the green alga Dunaliella tertiolecta. A time-
Omri Avidan, Sergey Malitsky, Uri Pick
doaj   +1 more source

Modification of thin films induced by slow heavy ions analysed with PIXE and SRIM [PDF]

open access: yes, 2015
In the present work the particle induced X-rays (PIXE) emitted during interaction of inert and active slow heavy (HI) ions with specially prepared thin films were measured.
Antoszewska-Moneta, Malgorzata   +2 more
core   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

HPLC-DAD Determination of Iodide in Mineral Waters on Phosphatidylcholine Column

open access: yesMolecules, 2019
Iodine is an essential nutrient necessary for the production of thyroid hormones. A valuable source of iodide, which is the bio-available iodine form could be mineral waters offered by different spas.
Małgorzata Tatarczak-Michalewska   +4 more
doaj   +1 more source

Mangiferin-Loaded Smart Gels for HSV-1 Treatment

open access: yesPharmaceutics, 2021
Infections due to HSV-1 affect many people all over the world. To counteract this pathology, usually characterized by perioral sores or by less frequent serious symptoms including keratitis, synthetic antiviral drugs are employed, such as acyclovir ...
Mariaconcetta Sicurella   +7 more
doaj   +1 more source

混合フォスファチジルコリン水溶液におけるひも状ミセル構造の形成 [PDF]

open access: yes, 2015
東京海洋大学博士学位論文 平成26年度(2014) 応用生命科学 課程博士 甲第339号指導教員: 松川真吾全文公表年月日: 2014-12 ...
Fafaungwithayakul Natdanai
core   +1 more source

PH regulation of amphotericin B channels activity in the bilayer lipid membrane [PDF]

open access: yes, 2016
Background: Amphotericin B (AmB) is a polyene antibiotic frequently applied in the treatment of systemic fungal infections in spite of its secondary effects.
Ashrafpour, M.   +2 more
core   +2 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

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