Results 41 to 50 of about 160,241 (340)

混合フォスファチジルコリン水溶液におけるひも状ミセル構造の形成 [PDF]

open access: yes, 2015
東京海洋大学博士学位論文 平成26年度(2014) 応用生命科学 課程博士 甲第339号指導教員: 松川真吾全文公表年月日: 2014-12 ...
Fafaungwithayakul Natdanai
core   +1 more source

Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]

open access: yes, 2006
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill   +44 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Structural elements that govern Sec14-like PITP sensitivities to potent small molecule inhibitors[S]

open access: yesJournal of Lipid Research, 2016
Sec14-like phosphatidylinositol transfer proteins (PITPs) play important biological functions in integrating multiple aspects of intracellular lipid metabolism with phosphatidylinositol-4-phosphate signaling.
Danish Khan   +4 more
doaj   +1 more source

Phosphatidylcholine transfer protein from bovine liver contains highly unsaturated phosphatidylcholine species [PDF]

open access: yesFEBS Letters, 1996
The phosphatidylcholine transfer protein (PC‐TP) from bovine liver contains one molecule of non‐covalently bound PC. In order to gain more insight into the physiological function of PC‐TP, PC was extracted from bovine liver PC‐TP and its molecular species composition identified by fast atom bombardment mass spectrometry.
Geijtenbeek, T. B.   +3 more
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Generation of Choline for Acetylcholine Synthesis by Phospholipase D Isoforms [PDF]

open access: yes, 2001
DEDICATION: This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn, Jan Krzysztof   +2 more
core   +3 more sources

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Dysregulation of of phospholipid-specific phagocytosis by B1 B cells in diet-induced obese mice [PDF]

open access: yes, 2016
B1 B cells have received increasing attention recently due to their newly discovered phagocytic and microbicidal capabilities. Several studies have demonstrated that B1 cells can phagocytize polystyrene fluorescent particles, bacteria (Staphylococcus ...
Vo, Hung
core   +1 more source

Incorporation of cytochrome oxidase into cardiolipin bilayers and induction of nonlamellar phases. [PDF]

open access: yes, 1990
Cytochrome oxidase from beef heart has been lipid-substituted with beef heart cardiolipin. The lipid phase behavior and protein aggregation state of the reconstituted complexes have been studied with 31P NMR, freeze-fracture electron microscopy, and ...
Knowles, P., Marsh, D., Powell, G.
core   +2 more sources

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