Results 41 to 50 of about 155,795 (339)

Astrocytes are mainly responsible for the polyunsaturated fatty acid enrichment in blood–brain barrier endothelial cells in vitro

Journal of Lipid Research, 1998
To determine the respective roles of endothelial cells from brain capillaries and astrocytes in the conversion of circulating 18:2n–6 and 18:3n–3 into 20:4n–6 and 22:6n–3, respectively, a coculture of the two cell types mimicking the in vivo blood–brain ...
N. Bernoud, L. Fenart, C. Bénistant, J.F. Pageaux, M.P. Dehouck, P. Molière, M. Lagarde, R. Cecchelli, J. Lecerf   +8 more
doaj   +1 more source

Analytic models for mechanotransduction: gating a mechanosensitive channel [PDF]

, 2003
Analytic estimates for the forces and free energy generated by bilayer deformation reveal a compelling and intuitive model for MscL channel gating analogous to the nucleation of a second phase.
Betanzos, Blount, Chang, Dan, Frauenfelder, Gillespie, Goulian, Gullingsrud, Helfrich, Huang, Keller, Killian, Nielsen, Ou, P. Wiggins, Perozo, Perozo, Powl, R. Phillips, Sachs, Strop, Sukharev, Yoshimura   +22 more
core   +2 more sources

Effects of diacylglycerols on conformation of phosphatidylcholine headgroups in phosphatidylcholine/phosphatidylserine bilayers

Biophysical Journal, 1995
The effects of five diacylglycerols (DAGs), diolein, 1-stearoyl,2-arachidonoyl-sn-glycerol, dioctanoylglycerol, 1-oleoyl,2-sn-acetylglycerol, and dipalmitin (DP), on the structure of lipid bilayers composed of mixtures of phosphatidylcholine and phosphatidylserine (4:1 mol/mol) were examined by 2H nuclear magnetic resonance (NMR ...
Dan Borchardt, D.S. Lester, Raphael Zidovetzki, Edward M. Goldberg   +3 more
openaire   +2 more sources

Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT[S]

Journal of Lipid Research, 2015
Mice that lack phosphatidylethanolamine N-methyltransferase (Pemt−/− mice) are protected from high-fat (HF) diet-induced obesity. HF-fed Pemt−/− mice show higher oxygen consumption and heat production, indicating that more energy might be utilized for ...
Xia Gao, Jelske N. van der Veen, Carlos Fernandez-Patron, Jean E. Vance, Dennis E. Vance, René L. Jacobs   +5 more
doaj   +1 more source

Development and Validation of a Simple Method to Quantify Contents of Phospholipids in Krill Oil by Fourier-Transform Infrared Spectroscopy

Foods, 2021
This study focuses on developing a quantification method for phosphatidylcholine (PC) and total phospholipid (PL) in krill oil using Fourier-transform infrared (FT-IR) spectroscopy.
Se-Eun Park, Hyo-Yeon Yu, Sangdoo Ahn
doaj   +1 more source

Changes in membrane lipids drive increased endocytosis following Fas ligation [PDF]

, 2017
Once activated, some surface receptors promote membrane movements that open new portals of endocytosis, in part to facilitate the internalization of their activated complexes.
Degli Esposti, Mauro, Garofalo, Tina, Khosravi Far, Roya, Longo, Agostina, Malorni, Walter, Matarrese, Paola, Misasi, Roberta, Recalchi, Serena, Sorice, Maurizio, Tinari, Antonella   +9 more
core   +1 more source

Phosphatidylcholine protects against the hepatotoxicity of acrylamide via maintaining metabolic homeostasis of glutathione and glycerophospholipid

Food Science and Human Wellness
Acrylamide is classified as a Class 2A carcinogen and mainly metabolized to produce hepatotoxicity. Phosphatidylcholine is thought to protect the liver from damage, but the protective role of phosphatidylcholine on acrylamide-exposed metabolic disorders ...
Yaoran Li, Wei Jia, Yiju Zhang, Yong Wu, Li Zhu, Jingjing Jiao, Yu Zhang   +6 more
doaj   +1 more source

Quantitation of cholesterol crystallization from supersaturated model bile1

Journal of Lipid Research, 2002
Cholesterol crystallization is an essential step in gallstone formation. Although spectrophotometry and nephelometry have been used for quantitation of crystallization, potential effects of crystal size and shape have not been evaluated.
Piero Portincasa, Niels G. Venneman, Antonio Moschetta, André van den Berg, Giuseppe Palasciano, Gerard P. vanBerge-Henegouwen, Karel J. van Erpecum   +6 more
doaj   +1 more source

Generation of Choline for Acetylcholine Synthesis by Phospholipase D Isoforms [PDF]

, 2001
DEDICATION: This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine, who perished in the terrorist attacks of September 11, 2001 ...
Blusztajn, Jan Krzysztof, Frohman, Michael A, Zhao, Di   +2 more
core   +3 more sources

Roles and Mechanisms of Choline Metabolism in Nonalcoholic Fatty Liver Disease and Cancers

Frontiers in Bioscience-Landmark
Choline participates in three major metabolic pathways: oxidation, phosphorylation, and acetylation. Through oxidation, choline is converted to betaine and contributes to methyl metabolism and epigenetic regulation.
Xin Chen, Wenying Qiu, Xuqian Ma, Linli Ren, Mingqian Feng, Sheng Hu, Chang Xue, Runzhi Chen   +7 more
doaj   +1 more source