Results 81 to 90 of about 155,795 (339)

An efficient synthesis of phosphatidylcholines.

Journal of Lipid Research, 1990
This article deals with two of the major steps involved in phospholipid synthesis: the preparation of the optically pure precursors, sn-glycero-3-phosphocholine (GPC) and -ethanolamine, from a convenient lipid source such as egg yolk, and acylation of hydroxyl groups present in those precursors involving an acid to yield the corresponding phospholipid.
openaire   +4 more sources

Preferential Membrane Remodeling on Curved Biointerfaces Induced by Conjugated Oligoelectrolyte

Advanced Materials Interfaces, EarlyView.
This study explores how membrane shape influences the interaction of conjugated oligoelectrolytes (COEs) with lipid bilayers. Using a curved biointerface composed of nanobar arrays and supported lipid bilayers, it is revealed that COE intercalation preferentially remodels curved regions, forming distinct structures. These findings highlight the role of
Xinwen Miao, Samuel Jun Wei Chan, Sian Kang Chong, Xiangfu Guo, James Chin Shing Ho, Atul N. Parikh, Guillermo Carlos Bazan, Wenting Zhao   +7 more
wiley   +1 more source

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Structural elements that govern Sec14-like PITP sensitivities to potent small molecule inhibitors[S]

Journal of Lipid Research, 2016
Sec14-like phosphatidylinositol transfer proteins (PITPs) play important biological functions in integrating multiple aspects of intracellular lipid metabolism with phosphatidylinositol-4-phosphate signaling.
Danish Khan, Kaitlyn R. McGrath, Oleksandra Dorosheva, Vytas A. Bankaitis, Ashutosh Tripathi   +4 more
doaj   +1 more source

Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen. [PDF]

, 1988
Cells of the rat neuronal line, PC12, adhere well to substrates coated with laminin and type IV collagen, but attach poorly to fibronectin. Adhesion and neurite extension in response to these extracellular matrix proteins are inhibited by Fab fragments ...
Damsky, CH, Reichardt, LF, Tomaselli, KJ
core   +1 more source

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

Pulmonary Uptake of Liposomal Phosphatidylcholine [PDF]

Pediatric Research, 1980
Liposomes prepared with phosphatidylcholine (PC) labeled with [1-14C]-dipalmitoyl-PC, dicetylphosphate, cholesterol (molar ratio 7:2:1) were injected into the right ear vein of 2-month-old male rabbits. At 5, 60, and 120 min after injection, organs were removed and analyzed for [14C]-PC. Lung, liver, and spleen took up the [14C]-PC by 5 min.
Richard D. Zachman, Francis H.C. Tsao
openaire   +3 more sources

Label‐Free Characterization of Lipid Interfaces Using Plasmonic Gold Nanorods as Optically Active Nanosensors

Advanced Optical Materials, EarlyView.
A label‐free plasmonic nanosensor platform is presented based on single gold nanorods for the nanometric characterization of lipid interfaces. By correlating optical scattering signals with membrane packing and refractive index, this approach enables the detection of gel‐to‐fluid transitions in lipid interfaces, offering a robust, high‐resolution ...
Alfredo Casasnovas‐Melián, Natalia Robles‐Anda, Lucía Labrador‐Páez, Florian D. Kofler, Jaime Hinojosa‐Platero, Elena Junquera, Miguel A. Sacristán, Iván López‐Montero, Ainhoa Collada, Antonio Cruz, Jesús Pérez‐Gil, Rubén Ahijado‐Guzmán, Andrés Guerrero‐Martínez   +12 more
wiley   +1 more source

Lipid Ion Channels

, 2010
The interpretation electrical phenomena in biomembranes is usually based on the assumption that the experimentally found discrete ion conduction events are due to a particular class of proteins called ion channels while the lipid membrane is considered ...
Heimburg, Thomas
core   +1 more source

Channel-forming activity of syringopeptin 25 A in mercury-supported phospholipid monolayers and negatively charged bilayers [PDF]

, 2016
Interactions of the cationic lipodepsipeptide syringopeptin 25 A (SP25A) with mercury-supported dioleoylphosphatidylcholine (DOPC), dioleoylphosphatidylserine (DOPS) and dioeleoylphosphatidic acid (DOPA) self-assembled monolayers (SAMs) were investigated
Becucci, Lucia, Fiore, Alberto, Guidelli, Rolando, Scaloni, Andrea, Toppi, Arianna   +4 more
core   +2 more sources