Results 151 to 160 of about 74,461 (380)

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska   +18 more
wiley   +1 more source

Genetic causality of lipidomic and immune cell profiles in ischemic stroke

open access: yesFrontiers in Neurology
BackgroundIschemic stroke (IS) is a global health issue linked to lipid metabolism and immune cell responses. This study uses Mendelian randomization (MR) to identify genetic risk factors for IS subtypes using comprehensive genetic data from lipidomic ...
Haohao Chen   +9 more
doaj   +1 more source

DL- and PO-phosphatidylcholines as a promising learning and memory enhancer

open access: yesLipids in Health and Disease, 2011
In the water maze test, oral administration with 1,2-dilynoleoyl-sn-glycero-3-phosphocholine (DLPhtCho)(5 mg/kg) alone or DLPhtCho (5 mg/kg) plus 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPhtCho)(5 mg/kg) significantly shortened the prolonged ...
Nishizaki Tomoyuki   +2 more
doaj   +1 more source

Supramolecular Lubricating Hydrogel Microspheres Reshape Damaged Matrix Regeneration

open access: yesAdvanced Science, EarlyView.
The supramolecular lubricating hydrogel microspheres can provide stable mechanophysical protection at damaged matrix through interfacial hydration lubrication: in the early and middle stages, microspheres can actively provide microscale supramolecular lubrication (µ ≈ 0.04) for damaged matrix; in the late stage, the wear debris induced by shear and ...
Hui Yuan   +3 more
wiley   +1 more source

Mass spectrometry of the phosphatidyl amino alcohols: detection of molecular species and use of low voltage spectra and metastable scanning in the elucidation of structure

open access: yesJournal of Lipid Research, 1972
The basic fragmentation mechanisms occurring in the mass spectra of the phosphatidylcholines have been described previously, and evidence was adduced to show that many of the more abundant ions are related by electron impact-induced processes.
R.A. Klein
doaj  

Fundamentals of ion mobility spectrometry

open access: yes, 2018
Fundamental questions in ion mobility spectrometry have practical implications for analytical applications in general, and omics in particular, in three respects.
Gabelica, Valerie, Marklund, Erik
core   +1 more source

Structural characterization of unsaturated phosphatidylcholines using traveling wave ion mobility spectrometry.

open access: yesAnalytical Chemistry, 2009
A number of phosphatidylcholine (PC) cations spanning a mass range of 400-1000 Da are investigated using electrospray ionization mass spectrometry coupled with traveling wave ion mobility spectrometry (TWIMS). A high correlation between mass and mobility
Hugh Inkon Kim   +7 more
semanticscholar   +1 more source

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