Results 161 to 170 of about 74,461 (380)

Theranostic Toolbox for Neutrophil Functionalization

Advanced Science, EarlyView.
Here, neutrophil‐specific fluorine nanoparticles additionally equipped with either activating or inhibiting peptides for a background‐free 19F MRI‐based nanotheranostic approach are engineered. It is demonstrated that this approach is suitable to visualize and concomitantly direct neutrophil functionality depending on the specific requirements to ...
Pascal Bouvain, Kay‐Matthias Thomy, Anika Maria Prinz, Bodo Steckel, Shiwa Kadir, Alexandra Röhs, Jonas Schmitz, Claudia Dohle, Matthias Karg, Maria Grandoch, Ulrich Flögel, Sebastian Temme   +11 more
wiley   +1 more source

Untargeted lipidomics analysis in women with morbid obesity and type 2 diabetes mellitus: A comprehensive study.

PLoS ONE
There is a phenotype of obese individuals termed metabolically healthy obese that present a reduced cardiometabolic risk. This phenotype offers a valuable model for investigating the mechanisms connecting obesity and metabolic alterations such as Type 2 ...
Laia Bertran, Jordi Capellades, Sonia Abelló, Carmen Aguilar, Teresa Auguet, Cristóbal Richart   +5 more
doaj   +1 more source

Toy amphiphiles on the computer: What can we learn from generic models?

, 2009
Generic coarse-grained models are designed such that they are (i) simple and (ii) computationally efficient. They do not aim at representing particular materials, but classes of materials, hence they can offer insight into universal properties of these ...
Bernardes, Bhattacharya, Brannigan, Brannigan, Brannigan, Brannigan, Carmesin, Cooke, Cordomi, de Meyer, de Planque, de Vries, de Vries, Doi, Düchs, Düchs, Farago, Fraaije, Fraaije, Fraser, Fredrickson, Fredrickson, Ganesan, Gennis, Gompper, Grest, Gunn, Guo, Guo, Guo, Guo, Götz, Haas, Haas, Haas, Halley, Harroun, He, He, He, He, Helfand, Helfand, Helfrich, Huang, Israelachvili, Izvekov, Jain, Karaborni, Katsaras, Killian, Komura, Koynova, Koynova, Kranenburg, Kranenburg, Kranenburg, Larson, Larson, Lei, Lenz, Lenz, Li, Lindahl, Linhananta, Loison, Loison, Loison, Marrink, Marsh, Matsen, Matsen, Matsen, Maurits, Maurits, Müller, Müller, Müller-Plathe, Noguchi, Noguchi, Pabst, Pochan, Safran, Schmid, Schmid, Schmid, Schmid, Schmid, Schmid, Schmid, Schmidt, Sengupta, Sevink, Sevink, Sharpe, Shen, Shillcock, Shillcock, Shull, Shull, Smit, Smit, Smith, Soddemann, Soddemann, Stadler, Stadler, Sun, Tardieu, Tenchov, Varandas, Venturoli, Venturoli, von Gottberg, von Gottberg, Wang, Werner, Werner, Werner, West, Wheeler, Whitmore, Yamamoto, Zhang, Zhang   +124 more
core   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Impaired response of biliary lipid secretion to a lithogenic diet in phosphatidylcholine transfer protein-deficient mice

Journal of Lipid Research, 2005
Phosphatidylcholine transfer protein (PC-TP) is a cytosolic lipid transfer protein that is highly expressed in liver and catalyzes intermembrane transfer of phosphatidylcholines in vitro.
Michele K. Wu, Hideyuki Hyogo, Suresh K. Yadav, Phyllis M. Novikoff, David E. Cohen   +4 more
doaj  

Turnover of the glycerolipids of pumpkin leaves. The importance of phosphatidylcholine [PDF]

, 1970
P. Grattan Roughan
openalex   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

Advanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li, Wentai Shangguan, Wenxue Huang, Jie Zhao, Yuexuan Zhu, Ming Xie, Yao Yu, Qishen Yang, Jun Zheng, Lin Yang, Qi Sun, Leqian Li, Xinhang Shi, Yongyuan Xiao, Hai Huang, Bisheng Cheng, Peng Wu   +16 more
wiley   +1 more source

Controlling interactions in supported bilayers from weak electrostatic repulsion to high osmotic pressure

, 2012
Understanding interactions between membranes requires measurements on well-controlled systems close to natural conditions, in which fluctuations play an important role.
Charitat, Thierry, Daillant, Jean, Fragneto, Giovanna, Hemmerle, Arnaud, Lecuyer, Sigolène, Malaquin, Linda   +5 more
core   +2 more sources

The Structure of Lipids and Proteins Studied by Attenuated Total Reflection (ATR) Infrared Spectroscopy II. Oriented Layers of a Homologous Series: Phosphatidylethanolamine to Phosphatidylcholine [PDF]

, 1977
U. P. Fringeli
openalex   +1 more source

Covalent Organic Frameworks‐Delivered Reuterin Drives Trained Immunity in Tumor‐Associated Macrophages to Enhance Melanoma Immunotherapy via Glycerophospholipid Metabolism

Advanced Science, EarlyView.
Covalent organic framework (COF)‐reuterin induces trained immunity in tumor‐associated macrophages, promoting the generation of nitric oxide and reactive oxygen species, thereby enhancing the antitumor immune response. Additionally, COF‐Reuterin directly kills tumor cells while simultaneously eradicating pathogenic intratumoural bacteria.
Jian‐Gang Zhang, Xiao‐Mei Zhang, Xi Wu, Cheng‐Kai Zhou, Zhen‐Zhen Liu, Xue‐Yue Luo, Liang Zhang, Wei Chen, Yong‐Jun Yang   +8 more
wiley   +1 more source