Results 221 to 230 of about 74,461 (380)

Fluid phase lipid areas and bilayer thicknesses of commonly used phosphatidylcholines as a function of temperature.

Biochimica et Biophysica Acta, 2011
N. Kučerka, M. Nieh, J. Katsaras
semanticscholar   +1 more source

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Simplex-structured matrix factorisation: application of soft clustering to metabolomic data. [PDF]

Sci Rep
Liu W, Murphy TB, Brennan L.
europepmc   +1 more source

The stereochemical configuration of lysosomal phosphatidylcholine and phosphatidylethanolamine: comparison with lysobisphosphatidic acid.

, 1979
Anneli Joutti, O. Renkonen
openalex   +1 more source

Association between enteral essential fatty acids and plasma phospholipid essential fatty acids related immune response in critically ill adults with COVID‐19: A prospective cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Coronavirus disease 2019 (COVID‐19) is a complicated disease with widely varying outcomes. Up to 20% of unvaccinated, hospitalized patients infected with COVID‐19 may die during the initial three weeks. Our research shows that COVID‐19 infection results in rapid, remarkable change in the balance between essential fatty acid ...
Vera C. Mazurak, Irma Magaly Rivas‐Serna, Sarah R. Parsons, Md Monirujjaman, Krista E. Maybank, Oleksa G. Rewa, Andrew J. Cave, Caroline Richard, M. Thomas Clandinin   +8 more
wiley   +1 more source

Moderate-intensity exercise training uniquely modulates circulating lipid species beyond classical lipid levels in humans. [PDF]

EBioMedicine
Zhang Y, Zhang Z, Martinez-Tellez B, Di X, Kindt A, Kohler I, Osuna-Prieto FJ, Clark C, Drouin N, Harms A, Hankemeier T, Ruiz JR, Jurado-Fasoli L.   +12 more
europepmc   +1 more source

Exogenous oxidized phytosterol may modulate linoleic acid metabolism through upregulation of fatty acid desaturase in rats

Lipids, EarlyView.
Abstract Previous in vitro studies have indicated that oxidized phytosterol (OPS) exhibits some toxicity; however, the harmful effects of OPS on fatty acid metabolism are not completely understood yet. Therefore, this study examined the effects of exogenous phytosterol (PS) and OPS on growth parameters and lipid metabolism in rats.
Tomonari Koyama, Kyoichi Osada
wiley   +1 more source

Dysregulation of Monounsaturated Fatty Acids is Related to α‐Synuclein in Multiple System Atrophy

Movement Disorders, EarlyView.
Abstract Background Multiple system atrophy (MSA) is a neurodegenerative disease pathologically characterized by the presence of glial cytoplasmic inclusions (GCI) composed of α‐synuclein aggregates. In Parkinson's disease, increases in monounsaturated fatty acids (MUFA) in phospholipid membranes promote α‐synuclein binding, aggregation, and toxicity ...
Finula I. Isik, YuHong Fu, Russell Pickford, Qi Cheng, Yue Yang, Simon J.G. Lewis, Nicolas Dzamko, Glenda M. Halliday, Woojin Scott Kim   +8 more
wiley   +1 more source

Biallelic ELOVL1 Variants Are Linked to Hypomyelinating Leukodystrophy, Movement Disorder, and Ichthyosis

Movement Disorders, EarlyView.
Abstract Background Very long chain fatty acids (VLCFAs) are an integral component of myelin and the epidermal water barrier. Variants in genes encoding enzymes responsible for catalyzing the first and rate limiting step in the production of VLCFAs, elongation of VLCFAs (ELOVLs), underlie a novel group of metabolic disorders. Objectives The goal was to
Keit Men Wong, Reza Maroofian, Kolja Meier, Susann Diegmann, Tinatin Tkemaladze, Javeria Raza Alvi, Behnoosh Tasharrofi, Stephanie Efthymiou, Alexander Munchau, G. Christoph Korenke, Naif Almontashiri, Wafaa Eyaid, Amna Kashgari, Modhi Alotaibi, Jutta Gärtner, Brenda Huppke, Mostafa Asadollahi, Gocha Chikvinidze, Mohammad Keramatipour, Tipu Sultan, Holger Thiele, Peter Nürnberg, Markus H. Gräler, Henry Houlden, Peter Huppke   +24 more
wiley   +1 more source

A Pomegranate Polyphenol Extract Suppresses the Microbial Production of Proatherogenic Trimethylamine (TMA) in an In Vitro Human Colon Model

Molecular Nutrition &Food Research, EarlyView.
Trimethylamine N‐oxide (TMAO) is associated with various cardiometabolic and other diseases and can cause thrombosis and vascular inflammation. Dietary l‐carnitine and choline are metabolized by gut microbiota to trimethylamine (TMA), which is oxidized to TMAO in the liver.
Julia E. Haarhuis, Priscilla Day‐Walsh, Emad Shehata, George M. Savva, Barbora Peck, Mark Philo, Paul A. Kroon   +6 more
wiley   +1 more source