Results 231 to 240 of about 19,173 (307)

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

The FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger, Alice Wiedmann, Rayan Hassan M. Elshikhidriss, Thomas Brunner   +3 more
wiley   +1 more source

Lipidomics Based on HILIC-ESI-HRMS Reveal Subtle Changes in the Mitochondrial Phospholipidome of Mouse Embryonic Fibroblasts Expressing Pathogenic Variants of Human OPA1 Protein. [PDF]

Molecules
Castellaneta A, Losito I, Porcelli V, Barile S, Maresca A, Del Dotto V, Magnoni P, Zanna C, Guadalupi LS, Cinquepalmi V, Calvano CD, Chan DC, Carelli V, Palmieri L, Cataldi TRI.   +14 more
europepmc   +1 more source

Rescue of pATOM36‐depleted T. brucei by human MTCH1/2 reveals common features of protein insertases

The FEBS Journal, EarlyView.
Human MTCH1 and MTCH2 (with an N‐terminal extension) functionally complement the loss of pATOM36 in T. brucei, indicating that these evolutionarily distant proteins recognize a common set of substrates and share fundamental principles of mitochondrial outer membrane protein insertion. Structural analyses reveal a common hydrophilic cavity, supporting a
Stephan Berger, Markus Daniel Gerber, Torsten Ochsenreiter, Christoph von Ballmoos, André Schneider   +4 more
wiley   +1 more source

Local host fish-<i>Anisakis</i> spp. parasite lipid interplay: A lipidomic characterization of <i>Anisakis</i> larvae and parasitized tissue of its host fish, the European hake (<i>Merluccius merluccius</i>). [PDF]

Food Waterborne Parasitol
Monteiro JP, Sousa T, Atroch F, Rangel LF, Pardo CA, Ramos P, Santos MJ, Rey F, Calado R, Domingues MR.   +9 more
europepmc   +1 more source

Pemafibrate Improves Cholestatic Markers Regardless of the Presence of Primary Biliary Cholangitis

Hepatology Research, EarlyView.
Pemafibrate improves liver function markers related to bile flow in primary biliary cholangitis (PBC), but whether this effect is disease‐specific remains unclear. In this study, pemafibrate reduced these markers in patients with and without PBC, suggesting broader effects on bile flow beyond PBC.
Ryohei Tanigawa, Yoshiyuki Ueno, Hirokazu Takahashi, Ayumi Saito, Hideki Suganami, Atsushi Tanaka   +5 more
wiley   +1 more source

Lipid droplet associated protein HILPDA promotes hypoxia-induced ferroptosis by driving LPCAT3-mediated polyunsaturated phospholipids enrichment. [PDF]

PLoS One
Song Z, Li W, Zeng J, Wang X, Wang D, Liao X.   +5 more
europepmc   +1 more source

Systemic Lipidomics Identifies Altered Ceramide–Phospholipid Balance Associated With Periodontitis Severity: A Cross‐Sectional Study With 12‐Year Follow‐Up

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate whether periodontitis stage and grade are associated with circulating active lipid mediators and whether baseline lipid species predict periodontitis progression. Materials and Methods The study included 473 Finnish participants from the Parogene cohort undergoing coronary angiography, with 12‐year follow‐up data available ...
Minja Tuomivaara, Anne‐Mari Halme, Muhammed Manzoor, Elina Salasuo, Susanna Paju, Päivi Mäntylä, Kåre Buhlin, Laura Lahdentausta‐Suomalainen, Reijo Laaksonen, Juha Sinisalo, Pirkko Pussinen, Aino Salminen   +11 more
wiley   +1 more source

Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma. [PDF]

EMBO Mol Med
Jonsson G, Oliveira T, Hofmann M, Lemberger U, Stejskal K, Krššáková G, Sakic I, Novatchkova M, Mereiter S, Grabmann G, Köcher T, Koglgruber R, Kikic Z, Camano Páez S, Luna Sanchez B, Díez Nicolás V, Rechberger GN, Züllig T, Hagelkruys A, Englinger B, Schmidinger M, Penninger JM.   +21 more
europepmc   +1 more source

Temperature, but not acidification, influences the growth and lipid profile of juvenile sand whiting, Sillago ciliata (Cuvier 1829)

Journal of Fish Biology, EarlyView.
Abstract Seafood provides an essential source of macro‐ and micronutrients for coastal communities worldwide. Climate change is a key threat to seafood security, altering the sizes, abundances, distributions, physiology and ecological interactions of fisheries species, and increasingly, there is evidence of impacts to seafood nutritional quality.
Tanika C. Shalders, Melissa Tan, Karina C. Hall, Melinda A. Coleman, Brendan Kelaher, Curtis Champion, Kirsten Benkendorff   +6 more
wiley   +1 more source

Integrated LC-MS-based lipidomics and transcriptomics reveal lipid heterogeneity and flavour variation in different cuts of muscles from Sadumont lamb. [PDF]

Food Chem (Oxf)
Guo T, Xing B, Nie R, Wang W, Liu N, An X, Qi J, Wang Y.   +7 more
europepmc   +1 more source