Results 241 to 250 of about 80,395 (343)

Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi. [PDF]

PLoS Pathog
Gwynne PJ, Bourgeois JS, Pandit A, Asara JM, Hu LT.   +4 more
europepmc   +1 more source

Dry Deposition Strategies for MALDI–MS Imaging: Principles, Advances and Emerging Applications

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Matrix‐assisted laser desorption/ionisation mass spectrometry imaging (MALDI–MSI) has become a pivotal tool in biomedical research, enabling untargeted, spatially resolved analysis of molecular species in complex biological tissues. Among the critical steps in MALDI–MSI workflows, matrix deposition significantly influences sensitivity, spatial
Toufik Mahamdi, Oscar Yanes
wiley   +1 more source

Metabolomic and chemometric profiling of crimson grapes during drying and its impact on antidiabetic activity. [PDF]

NPJ Sci Food
Abo-Atya DM, Ghareeb DA, Aldahmash B, Khalifa SAM, El-Seedi HR, Shawky E, Ghallab DS.   +6 more
europepmc   +1 more source

Wooden‐Tip Electrospray Ionization Mass Spectrometry Combined With Machine Learning for Differentiating Thyroid Tumours

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Direct mass spectrometry (MS) analysis of human tissues at the molecular level has great potential for clinical diagnosis and biomarker discovery. However, conventional MS‐based analytical methods often require complicated and time‐consuming sample preparation, which limits their applicability in rapid clinical analysis.
Da‐Sheng Liu, Li Liu, Baixue Wang, Jianfeng Zhang, Hong‐Guo Lin, Xiang‐Xiong Huang, Kang‐Jian Deng, Yu‐Teng Zhou, Yunlong Pan, Bin Hu, Xue‐Yang Huang   +10 more
wiley   +1 more source

Very long-chain saturated fatty acids in plasma lipids: association with cardiometabolic risk influenced by lipid interactions. [PDF]

Cardiovasc Diabetol
Domínguez-López I, Eichelmann F, Prada M, Schulze MB.   +3 more
europepmc   +1 more source

Physiology, pathology and therapeutic potential of microglial triggering receptor expressed on myeloid cells 2 signalling: A narrative update

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong, Libin Shen, Daqing Ma, Jinchao Hou   +3 more
wiley   +1 more source

Plasma lipid remodeling during the early recovery phase after myocardial infarction. [PDF]

Sci Rep
Myszko M, Bychowski J, Radziwon P, Skrzydlewska E, Łuczaj W.   +4 more
europepmc   +1 more source

Abcb4 Haploinsufficiency Sensitises Mice to a Diet‐Induced PSC‐Like Hepatobiliary Phenotype With Gallstone Formation

Liver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT ABCB4 translocates phospholipids (PL) into bile to buffer the toxicity of bile acids (BA) and free cholesterol (CHOL). While recessively inherited ABCB4 deficiency causes childhood Progressive Familial Intrahepatic Cholestasis type 3, haploinsufficiency has been linked to adult‐onset hepatobiliary diseases.
Eric L. Bell, Youhwa Jo, Jennifer K. Truong, Nathan O. Fuller, John P. Miller, Alastair S. Garfield, Robert O. Hughes   +6 more
wiley   +1 more source

Beyond Feature Selection: Interpretable Machine Learning for Mechanistic Insights in Metabolomics. [PDF]

Biology (Basel)
Bai H, Ren Y, Wang J, Wang Y, Yang Y.
europepmc   +1 more source

Development and Optimization of a Nanophytosomes‐Based Thermogel as a Topical Anti‐Psoriatic for Increased Solubility and Bioavailability

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Schematic illustration of the development, optimization, and therapeutic evaluation of the Leucas aspera phytosome‐based thermogel for topical antipsoriatic therapy, highlighting its enhanced solubility, skin deposition, and in vivo efficacy in an imiquimod‐induced psoriasis model. Created with BioRender.com.
Ananda Kumar Chettupalli, Thatipally Rajeshwar, Sarad Pawar Naik Bukke   +2 more
wiley   +1 more source