Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management
This review highlights the transformation of niclosamide, a repurposed drug, through molecular science strategies to overcome its pharmacokinetic limitations. Emphasizing novel nanohybrid technologies and delivery platforms, the article explores their therapeutic potential in targeting the complex pathophysiology of long COVID, paving the way for ...
Sanoj Rejinold N+3 more
wiley +1 more source
Lipid Subclasses Differentiate Insulin Resistance by Triglyceride-Glucose Index. [PDF]
Naja K+3 more
europepmc +1 more source
Localization of phosphatidylcholine in outer envelope membrane of spinach chloroplasts. [PDF]
Albert-Jean Dorne+3 more
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Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu+12 more
wiley +1 more source
Metabolomic Profiles and Differential Constituents of <i>Andrographis paniculata</i> (Burm. f.) in Different Growth Stages and Parts. [PDF]
Hu E+8 more
europepmc +1 more source
Arachidonyl transfer from diacyl phosphatidylcholine to ether phospholipids in rat platelets [PDF]
Odile Colard, M Breton, G. Béréziat
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This study presents a novel method for rapidly evaluating dermal drug delivery systems (DDSs). Using mass spectrometry imaging and automated data analysis, it visualizes drug distribution within skin layers in under 10 min. Tested with three nanoscale DDSs for antifungal terbinafine, the approach reveals key differences in drug permeation depth and ...
Ravit Yakobi Arancibia+9 more
wiley +1 more source
Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation. [PDF]
Petry HG, Saini N, Smith SM, Mooney SM.
europepmc +1 more source
Fatty acids stimulate phosphatidylcholine synthesis and CTP:choline-phosphate cytidylyltransferase in type II pneumocytes isolated from adult rat lung [PDF]
Ralph Burkhardt+3 more
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Investigating Impacts of Amino Acids on the Structural Stability of Anionic Biomembranes
Glycine and lysine interact with the anionic membrane composed of POPC and POPG (1 : 1). Lysine partitions into the membrane and induces structural alterations, while the membrane remains impermeable to it. In contrast, glycine causes no physicochemical damage and permeates through the membrane.
Arslan Siddique+6 more
wiley +1 more source