Results 261 to 270 of about 74,461 (380)

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler   +7 more
wiley   +1 more source

Oxidized phosphatidylcholines facilitate phospholipid flip-flop in liposomes.

open access: yesBiophysical Journal, 2011
R. Volinsky   +5 more
semanticscholar   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Merging metabolomics and genomics provides a catalog of genetic factors that influence molecular phenotypes in pigs linking relevant metabolic pathways. [PDF]

open access: yesGenet Sel Evol
Bovo S   +18 more
europepmc   +1 more source

Encapsulants Affect Liposome Surface Interactions with Biological Systems

open access: yesSmall, EarlyView.
This study demonstrates how dyes encapsulated in liposomes, lipid bilayer nanostructures with an inner aqueous core, affect liposome surface chemistry and interactions with biological matrices. This is achieved by investigating the effects of dye interactions with liposomal membranes using spectroscopy, small‐angle X‐ray scattering, and a bioassay ...
Clemens Spitzenberg   +7 more
wiley   +1 more source

Serum Metabolite Profile in Progressive Versus Nonprogressive Alcohol-Related Liver Disease: A Cross-Sectional Metabolomics Study. [PDF]

open access: yesLiver Int
Puhakka E   +11 more
europepmc   +1 more source

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