Results 101 to 110 of about 3,564 (210)

Outcomes for Early Liver Transplantation for Alcohol-associated Liver Disease in High-acuity Liver Transplant Recipients With Alcohol Use Disorder

Transplantation Direct
Background. Alcohol use disorder (AUD) incidence is increasing, and alcohol-associated liver disease is the leading indication for liver transplantation (LT) in the United States. Many centers have adopted “early LT” (ELT) for patients with
Andrea M. Meinders, MD, Ashton A. Connor, MD, PhD, John Ontiveros, LCSW, Ahmed Elaileh, MD, Khush Patel, MD, MS, Jason Todd, BS, MBA, Danika L. Nottage, BS, BMSc, Elizabeth W. Brombosz, PhD, Linda W. Moore, PhD, Caroline J. Simon, MD, Yee Lee Cheah, MD, Mark J. Hobeika, MD, Constance M. Mobley, MD, PhD, Ashish Saharia, MD, Tamneet Basra, MD, Sudha Kodali, MD, MSPH, David W. Victor, III, MD, Brian P. Lee, MD, Norah Terrault, MD, Xian C. Li, PhD, A. Osama Gaber, MD, R. Mark Ghobrial, MD, PhD   +21 more
doaj   +1 more source

Phosphatidylethanol (B-PEth) and other direct and indirect biomarkers of alcohol consumption

When identifying, preventing and treating alcohol use disorder, a correct estimation of alcohol intake is essential. An objective marker is preferred as self-reported alcohol intake suffers from bias, and the use of alcohol biomarkers is increasing ...
De Bejczy, Andrea,
core   +1 more source

Lipid peroxidation products and superoxide dismutase activity in women depending on the phosphatidylethanol level in the first trimester of pregnancy

Acta Biomedica Scientifica
Background. Even small amounts of alcohol have an extremely negative effect on the fetus, especially in the early stages of gestation. It is known that ethanol promotes the formation of free radicals, but there is no data on the nature of the oxidative ...
E. A. Novikova, N. V. Semenova, A. N. Karacheva, O. A. Nikitina, A. Yu. Marianian, T. A. Bairova, A. V. Belskikh, E. V. Belyaeva, A. Yu. Sambyalova, O. A. Ershova, L. I. Kolesnikova   +10 more
doaj   +1 more source

Alcohol Relapse After Liver Transplantation: Advances in Risk Stratification, Biomarker Integration, and Post-transplant Care

Gastro Hep Advances
Alcohol-associated liver disease (ALD) is now the primary indication for liver transplantation (LT) in the United States. While outcomes after LT for ALD are generally excellent, the possibility of post-LT alcohol relapse raises ongoing clinical, ethical,
Vincent Pedulla, Alyson Kaplan
doaj   +1 more source

PEth as a screening measure for alcohol problems in psychiatric care

A register-based cohort study on the use of phosphatidylethanol (PEth) in ...
Joar Guterstam
core   +2 more sources

N-acetyl cysteine for the treatment of alcohol use disorder: study protocol for a multi-site, double-blind randomised controlled trial (NAC-AUD study)

BMJ Open
Introduction Current treatments for alcohol use disorders (AUD) have limited efficacy. A previous 28-day pilot trial of N-acetyl cysteine (NAC) vs placebo found NAC to be feasible and safe, with evidence of improvement on some measures of alcohol ...
Michael Berk, Paul S Haber, Tim Slade, Paul J Clark, Jason P Connor, Andrew Baillie, Kirsten Morley, Shalini Arunogiri, Mary Lou Chatterton, D Lubman   +9 more
doaj   +1 more source

Humoral immune response to phosphatidylethanol

, 2011
Abstract Heavy alcohol consumption places a substantial burden on health all over the world. Metabolites of alcohol evoke alterations that lead to tissue damage in many organs. Phosphatidylethanol (PEth) is a unique phospholipid formed in the cellular membranes during the metabolism of ethanol after alcohol consumption.
openaire   +1 more source

Leber Hereditary Optic Neuropathy Case Report: Clinical Presentation and Treatment with Idebenone Reinforce the Evidence for m.3866T>C as a Causative Variant

Case Reports in Ophthalmology
Introduction: Leber hereditary optic neuropathy (LHON) is a mitochondrial disorder that typically presents with painless, central visual loss, hyperaemia of the optic nerve head, and peripapillary telangiectasias.
Øystein K. Jørstad, Stine Skaar, Harald Strand, Oddveig Røsby, Ruth Therese Brokstad, Pål A. Rønning   +5 more
doaj   +1 more source

Nonaqueous capillary electrophoresis for analysis of the ethanol consumption biomarker phosphatidylethanol

, 2008
Nonaqueous CE (NACE) methodology was developed for the separation and determination of phosphatidylethanol (Peth), a new biomarker of ethanol intake.
Varga, Arthur,, Nilsson, Staffan,, Lund University.   +2 more
core   +1 more source

The relationship of Phosphatidylethanol and Cholesterol in Non-Human Primates

Background: Phosphatidylethanol (PEth) is a metabolite of ethanol, therefore a direct detector of alcohol in the human body, which is used to identify and monitor severity of alcohol events.
Nguyen, Samantha
core   +1 more source