Results 101 to 110 of about 3,448 (206)

Quantifying Phosphatidylethanol from Dried Blood Spots by Gas Chromatography-Mass Spectrometry​

Phosphatidylethanol (PEth) is a phase II biomarker formed in the walls of red blood cells that shows excellent sensitivity and specificity as a screening biomarker for chronic alcohol use and abuse.
Morey, Samantha J
core   +1 more source

Phosphatidylethanol levels and their association with withdrawal severity among individuals with severe alcohol use disorder seeking inpatient withdrawal management

Frontiers in Psychiatry
IntroductionThis study aimed to determine if phosphatidylethanol (PEth) levels are associated with alcohol withdrawal severity among individuals seeking inpatient withdrawal management.MethodsA prospective study enrolled individuals undergoing alcohol ...
Jeong Hoo Lee, Jeong Hoo Lee, Veronica Szpak, Lisa W. Vercollone, Peter R. Chai, Peter R. Chai, Charlotte E. Goldfine, Charlotte E. Goldfine, Samuel Maddams, Joji Suzuki, Joji Suzuki   +10 more
doaj   +1 more source

Outcomes for Early Liver Transplantation for Alcohol-associated Liver Disease in High-acuity Liver Transplant Recipients With Alcohol Use Disorder

Transplantation Direct
Background. Alcohol use disorder (AUD) incidence is increasing, and alcohol-associated liver disease is the leading indication for liver transplantation (LT) in the United States. Many centers have adopted “early LT” (ELT) for patients with
Andrea M. Meinders, MD, Ashton A. Connor, MD, PhD, John Ontiveros, LCSW, Ahmed Elaileh, MD, Khush Patel, MD, MS, Jason Todd, BS, MBA, Danika L. Nottage, BS, BMSc, Elizabeth W. Brombosz, PhD, Linda W. Moore, PhD, Caroline J. Simon, MD, Yee Lee Cheah, MD, Mark J. Hobeika, MD, Constance M. Mobley, MD, PhD, Ashish Saharia, MD, Tamneet Basra, MD, Sudha Kodali, MD, MSPH, David W. Victor, III, MD, Brian P. Lee, MD, Norah Terrault, MD, Xian C. Li, PhD, A. Osama Gaber, MD, R. Mark Ghobrial, MD, PhD   +21 more
doaj   +1 more source

Lipid peroxidation products and superoxide dismutase activity in women depending on the phosphatidylethanol level in the first trimester of pregnancy

Acta Biomedica Scientifica
Background. Even small amounts of alcohol have an extremely negative effect on the fetus, especially in the early stages of gestation. It is known that ethanol promotes the formation of free radicals, but there is no data on the nature of the oxidative ...
E. A. Novikova, N. V. Semenova, A. N. Karacheva, O. A. Nikitina, A. Yu. Marianian, T. A. Bairova, A. V. Belskikh, E. V. Belyaeva, A. Yu. Sambyalova, O. A. Ershova, L. I. Kolesnikova   +10 more
doaj   +1 more source

Assessing alcohol consumption across phosphatidylethanol levels using HDL-cholesterol as a predictor [PDF]

Aims: Prior research has established a correlation between increases of High-Density Lipoprotein Cholesterol (HDL-C) levels and alcohol consumption. This study aimed to explore the association between phosphatidylethanol (PEth) levels and the amount of ...
Mørland, Jørg Gustav, Høiseth, Gudrun, Hilberg, Thor, Jørgenrud, Benedicte Marie, Årving, Alexander Braadving, Vigerust, Elisabeth, Bogstrand, Stig Tore   +6 more
core   +1 more source

Alcohol Relapse After Liver Transplantation: Advances in Risk Stratification, Biomarker Integration, and Post-transplant Care

Gastro Hep Advances
Alcohol-associated liver disease (ALD) is now the primary indication for liver transplantation (LT) in the United States. While outcomes after LT for ALD are generally excellent, the possibility of post-LT alcohol relapse raises ongoing clinical, ethical,
Vincent Pedulla, Alyson Kaplan
doaj   +1 more source

N-acetyl cysteine for the treatment of alcohol use disorder: study protocol for a multi-site, double-blind randomised controlled trial (NAC-AUD study)

BMJ Open
Introduction Current treatments for alcohol use disorders (AUD) have limited efficacy. A previous 28-day pilot trial of N-acetyl cysteine (NAC) vs placebo found NAC to be feasible and safe, with evidence of improvement on some measures of alcohol ...
Michael Berk, Paul S Haber, Tim Slade, Paul J Clark, Jason P Connor, Andrew Baillie, Kirsten Morley, Shalini Arunogiri, Mary Lou Chatterton, D Lubman   +9 more
doaj   +1 more source

Leber Hereditary Optic Neuropathy Case Report: Clinical Presentation and Treatment with Idebenone Reinforce the Evidence for m.3866T>C as a Causative Variant

Case Reports in Ophthalmology
Introduction: Leber hereditary optic neuropathy (LHON) is a mitochondrial disorder that typically presents with painless, central visual loss, hyperaemia of the optic nerve head, and peripapillary telangiectasias.
Øystein K. Jørstad, Stine Skaar, Harald Strand, Oddveig Røsby, Ruth Therese Brokstad, Pål A. Rønning   +5 more
doaj   +1 more source

Phosphatidylethanol in Steatotic Liver Disease:Unveiling Alcohol Use and Enhancing Diagnostic Precision [PDF]

Accurately discerning the contribution of alcohol intake to the pathogenesis of steatotic liver disease (SLD) is fundamental to its classification, management, and prognosis.
Torp, Nikolaj; id_orcid
core   +1 more source

A physiologically-based digital twin for alcohol consumption—predicting real-life drinking responses and long-term plasma PEth

npj Digital Medicine
Alcohol consumption is associated with a wide variety of preventable health complications and is a major risk factor for all-cause mortality in the age group 15-47 years. To reduce dangerous drinking behavior, eHealth applications have shown promise.
Henrik Podéus, Christian Simonsson, Patrik Nasr, Mattias Ekstedt, Stergios Kechagias, Peter Lundberg, William Lövfors, Gunnar Cedersund   +7 more
doaj   +1 more source