Results 161 to 170 of about 3,564 (210)
Phosphatidylethanol in Rat Organs After Ethanol Exposure
Background: Phosphatidylethanol (PEth) is an abnormal phospholipid formed in mammalian cells that have been exposed to ethanol. It has been suggested that PEth mediates some of the damaging effects of ethanol on cells. This study was performed to investigate the level of PEth in organs of rats after in vivo alcohol exposure.Methods: Three exposure ...
Steina, Aradottir +2 more
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Enzymatic Synthesis and Thermotropic Behaviour of Phosphatidylethanol
Chemistry and Physics of Lipids, 1989Abstract Myristic and palmitic acid derivatives of phosphatidylethanol (PEt) were prepared by a transphosphatidylation reaction using phosphatidylcholine (PC)/ethanol catalyzed by phospholipase D. Yield of the procedure was 70–80%. The resulting phosphatidylethanol was purified by ion-exchange column chromatography and characterized by fast atom ...
Massimo Masserini +2 more
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Quantifying phosphatidylethanol from blood samples [PDF]
Disclosed herein is a method for quantifying phosphatidylethanol (“ PEth ”), direct ethanol biomarker, from a blood sample using gas chromatography mass spectrometry.
DEFRANCESCO JAMES VINCENT, AFSHAR MAJID
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Transfer of Phosphatidylethanol Between Lipoproteins
Alcoholism: Clinical and Experimental Research, 2004Background: Phosphatidylethanol (PEth) is an abnormal phospholipid formed only in the presence of ethanol. It has been recently shown that lipoprotein‐associated PEth may mediate the effects of ethanol on endothelial cells, and this may explain, at least in part, the beneficial effect of ethanol on atherosclerosis.
Marja K, Liisanantti +2 more
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Phosphatidylethanol in Blood as a Marker of Chronic Alcohol Use: A Systematic Review and Meta-Analysis [PDF]
The present paper aims at a systematic review of the current knowledge on phosphatidylethanol (PEth) in blood as a direct marker of chronic alcohol use and abuse. In March 2012, the search through “MeSH” and “free-text” protocols in the databases Medline/
Rafael Boscolo-Berto +2 more
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Method for Preparing Phosphatidylethanol
Chemistry of Natural Compounds, 2004A method has been developed for preparing the unique phospholipid phosphatidylethanol, which is a marker of human and animal alcohol intoxication and acts as an effective component of liposomal forms of medicinal compounds. The method consists of preparation of the diethyl ester of phosphatidic acid with subsequent removal of one ethyl by CsF in t ...
D. V. Arsenov +2 more
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Molecular Mechanics and Calorimetric Studies of Phosphatidylethanols
Archives of Biochemistry and Biophysics, 2001Phosphatidylethanols (PEths) are negatively charged diacyl phospholipids that are ubiquitously present in humans under the condition of alcohol intoxication. These lipids, derived in vivo from other naturally occurring phospholipids such as phosphatidylcholines (PC) via transphosphatidylation reaction as catalyzed by phospholipase D in the presence of ...
S, Li, H, Lin, G, Wang, C H, Huang
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ALCOHOLISM AND BIOSYNTHESIS OF PHOSPHATIDYLETHANOL
Nutrition Reviews, 2009The potential for synthesizing phosphatidylethanol is greater in lymphocytes of adult males with alcohol dependency and a family history of alcoholism than in control subjects. This distinctive characteristic may be a potential metabolic marker for the risk of alcoholism.
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Formation of phosphatidylethanol in rat brain by phospholipase D
Biochemical and Biophysical Research Communications, 1987The mechanism of phosphatidyl [14C]ethanol formation was studied in rat brain microsomal fraction. Phospholipase D and base-exchange enzymes were assayed with [14C]ethanol as substrate. Phospholipase D was found to catalyse the formation of phosphatidylethanol. The reaction was dependent on sodium-oleate as activating factor.
L, Gustavsson, C, Alling
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Blood Testing for Phosphatidylethanol
JAMAA 36-year-old man with obesity and dyslipidemia presented with elevated liver enzymes following a liver transplant to treat acute-on-chronic liver failure due to alcohol-associated hepatitis. What would you do next?
Areej, Mazhar, Amanda, Cheung
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