Results 161 to 170 of about 3,564 (210)

Phosphatidylethanol in Rat Organs After Ethanol Exposure

open access: yesAlcoholism: Clinical and Experimental Research, 2002
Background: Phosphatidylethanol (PEth) is an abnormal phospholipid formed in mammalian cells that have been exposed to ethanol. It has been suggested that PEth mediates some of the damaging effects of ethanol on cells. This study was performed to investigate the level of PEth in organs of rats after in vivo alcohol exposure.Methods: Three exposure ...
Steina, Aradottir   +2 more
core   +4 more sources
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Enzymatic Synthesis and Thermotropic Behaviour of Phosphatidylethanol

Chemistry and Physics of Lipids, 1989
Abstract Myristic and palmitic acid derivatives of phosphatidylethanol (PEt) were prepared by a transphosphatidylation reaction using phosphatidylcholine (PC)/ethanol catalyzed by phospholipase D. Yield of the procedure was 70–80%. The resulting phosphatidylethanol was purified by ion-exchange column chromatography and characterized by fast atom ...
Massimo Masserini   +2 more
exaly   +2 more sources

Quantifying phosphatidylethanol from blood samples [PDF]

open access: yes, 2021
Disclosed herein is a method for quantifying phosphatidylethanol (“ PEth ”), direct ethanol biomarker, from a blood sample using gas chromatography mass spectrometry.
DEFRANCESCO JAMES VINCENT, AFSHAR MAJID
core   +3 more sources

Transfer of Phosphatidylethanol Between Lipoproteins

Alcoholism: Clinical and Experimental Research, 2004
Background: Phosphatidylethanol (PEth) is an abnormal phospholipid formed only in the presence of ethanol. It has been recently shown that lipoprotein‐associated PEth may mediate the effects of ethanol on endothelial cells, and this may explain, at least in part, the beneficial effect of ethanol on atherosclerosis.
Marja K, Liisanantti   +2 more
openaire   +2 more sources

Phosphatidylethanol in Blood as a Marker of Chronic Alcohol Use: A Systematic Review and Meta-Analysis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2012
The present paper aims at a systematic review of the current knowledge on phosphatidylethanol (PEth) in blood as a direct marker of chronic alcohol use and abuse. In March 2012, the search through “MeSH” and “free-text” protocols in the databases Medline/
Rafael Boscolo-Berto   +2 more
exaly   +2 more sources

Method for Preparing Phosphatidylethanol

Chemistry of Natural Compounds, 2004
A method has been developed for preparing the unique phospholipid phosphatidylethanol, which is a marker of human and animal alcohol intoxication and acts as an effective component of liposomal forms of medicinal compounds. The method consists of preparation of the diethyl ester of phosphatidic acid with subsequent removal of one ethyl by CsF in t ...
D. V. Arsenov   +2 more
openaire   +1 more source

Molecular Mechanics and Calorimetric Studies of Phosphatidylethanols

Archives of Biochemistry and Biophysics, 2001
Phosphatidylethanols (PEths) are negatively charged diacyl phospholipids that are ubiquitously present in humans under the condition of alcohol intoxication. These lipids, derived in vivo from other naturally occurring phospholipids such as phosphatidylcholines (PC) via transphosphatidylation reaction as catalyzed by phospholipase D in the presence of ...
S, Li, H, Lin, G, Wang, C H, Huang
openaire   +2 more sources

ALCOHOLISM AND BIOSYNTHESIS OF PHOSPHATIDYLETHANOL

Nutrition Reviews, 2009
The potential for synthesizing phosphatidylethanol is greater in lymphocytes of adult males with alcohol dependency and a family history of alcoholism than in control subjects. This distinctive characteristic may be a potential metabolic marker for the risk of alcoholism.
openaire   +2 more sources

Formation of phosphatidylethanol in rat brain by phospholipase D

Biochemical and Biophysical Research Communications, 1987
The mechanism of phosphatidyl [14C]ethanol formation was studied in rat brain microsomal fraction. Phospholipase D and base-exchange enzymes were assayed with [14C]ethanol as substrate. Phospholipase D was found to catalyse the formation of phosphatidylethanol. The reaction was dependent on sodium-oleate as activating factor.
L, Gustavsson, C, Alling
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Blood Testing for Phosphatidylethanol

JAMA
A 36-year-old man with obesity and dyslipidemia presented with elevated liver enzymes following a liver transplant to treat acute-on-chronic liver failure due to alcohol-associated hepatitis. What would you do next?
Areej, Mazhar, Amanda, Cheung
openaire   +2 more sources

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