Causal relationship between plasma lipidome and 6 types of cancer: A Mendelian randomization study. [PDF]
Tang N, Tang J, Zhang J, Chen H, Yang R.
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This graphical abstract summarizes the current advances in dietary exosome‐like nanoparticles (ELNs), highlighting their biogenesis pathways (MVB‐dependent, vacuole‐mediated, and EXPO routes), molecular composition (nucleic acids, lipids, proteins, and bioactive compounds), and major preparation strategies including differential ultracentrifugation ...
Nidesha Randeni +3 more
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Lipid alterations in hereditary peripheral neuropathies: common mechanisms in disease heterogeneity? [PDF]
Kuipers K +5 more
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Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice
This study shows that oxidative changes in oocytes from aged female mice lead to lipid droplet accumulation and altered energy and retinoid metabolism. These changes persist in embryonic organs, triggering antioxidant responses in lipid‐rich tissues. Remarkably, altered profiles are transmitted across generations, reaching third generation, suggesting ...
Hafsa Gulzar +8 more
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Several endocannabinoids and amino acids may be biosynthetically converted to catecholamines <i>in vivo</i>. [PDF]
Fitzgerald PJ.
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Early‐life co‐consumption of galactose and glucose (hydrolyzed lactose) programs Drosophila melanogaster lifespan in a sex‐specific manner. Particularly, the co‐consumption of galactose and glucose programs extended lifespan when female flies were challenged by obesogenic diets later in life, and this is concomitant with remodeling of lipid metabolism,
Peixin Sun +7 more
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A Lipidomic Analysis Reveals Dynamic Changes of Polar Lipids for Oil Biosynthesis During Cotyledon Development in <i>Perilla frutescens</i>. [PDF]
Liu X +7 more
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A Multi‐Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice
A gut‐derived metabolic signature drives systemic aging phenotypes. Integrated multi‐omics profiling of young versus aged mice identifies a conserved aging signature characterized by the depletion of protective lysophosphatidylcholines (LPC 22:0) and the concurrent accumulation of pro‐oxidative microbial catabolites (TMAO, IAA).
Sanaullah Sajid +6 more
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Genetically predicted inflammatory protein mediate the association between lipidome and colon cancer. [PDF]
Jiawei S, Yixin J, Ting S, Yining G.
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Drosophila and mouse models of Alzheimer's disease exhibit lipid accumulation and neuroinflammation, leading to progressive impairments in memory, locomotion, sleep, circadian rhythms, and synaptic integrity. Knockdown of Dgat2 reduces lipid accumulation and neuroinflammatory signaling, rescuing these deficits and highlighting a conserved, crossspecies
Archana Yadav +7 more
wiley +1 more source

