Results 231 to 240 of about 72,154 (294)

Trends in Dietary Exosome‐Like Nanoparticles: Preparation, Nutritional Functions, Bioactive Delivery Efficacy, Human Health Effects, and Future Product Development

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
This graphical abstract summarizes the current advances in dietary exosome‐like nanoparticles (ELNs), highlighting their biogenesis pathways (MVB‐dependent, vacuole‐mediated, and EXPO routes), molecular composition (nucleic acids, lipids, proteins, and bioactive compounds), and major preparation strategies including differential ultracentrifugation ...
Nidesha Randeni   +3 more
wiley   +1 more source

Lipid alterations in hereditary peripheral neuropathies: common mechanisms in disease heterogeneity? [PDF]

open access: yesMol Neurodegener
Kuipers K   +5 more
europepmc   +1 more source

Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
This study shows that oxidative changes in oocytes from aged female mice lead to lipid droplet accumulation and altered energy and retinoid metabolism. These changes persist in embryonic organs, triggering antioxidant responses in lipid‐rich tissues. Remarkably, altered profiles are transmitted across generations, reaching third generation, suggesting ...
Hafsa Gulzar   +8 more
wiley   +1 more source

Lactose‐Derived Carbohydrates Induce Sexually Dimorphic Nutritional Programming Effects on Lifespan in Drosophila melanogaster

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
Early‐life co‐consumption of galactose and glucose (hydrolyzed lactose) programs Drosophila melanogaster lifespan in a sex‐specific manner. Particularly, the co‐consumption of galactose and glucose programs extended lifespan when female flies were challenged by obesogenic diets later in life, and this is concomitant with remodeling of lipid metabolism,
Peixin Sun   +7 more
wiley   +1 more source

A Multi‐Organ Atlas Links Gut Microbial Metabolites to Systemic Redox Changes in Aging Mice

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
A gut‐derived metabolic signature drives systemic aging phenotypes. Integrated multi‐omics profiling of young versus aged mice identifies a conserved aging signature characterized by the depletion of protective lysophosphatidylcholines (LPC 22:0) and the concurrent accumulation of pro‐oxidative microbial catabolites (TMAO, IAA).
Sanaullah Sajid   +6 more
wiley   +1 more source

Regulation of Lipid Dysmetabolism and Neuroinflammation Progression Linked With Alzheimer's Disease Through Modulation of Dgat2

open access: yesAging Cell, Volume 25, Issue 3, March 2026.
Drosophila and mouse models of Alzheimer's disease exhibit lipid accumulation and neuroinflammation, leading to progressive impairments in memory, locomotion, sleep, circadian rhythms, and synaptic integrity. Knockdown of Dgat2 reduces lipid accumulation and neuroinflammatory signaling, rescuing these deficits and highlighting a conserved, crossspecies
Archana Yadav   +7 more
wiley   +1 more source

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