Results 241 to 250 of about 82,133 (342)

Mendelian randomization analysis of lipidomic profiles and thyroid cancer risk in European populations. [PDF]

Discov Oncol
Li S, Yu H, Zhang D, Li Y.
europepmc   +1 more source

Comparison of the Effects of Cholesterol or 3β-Hydroxy-5-Oxo-5,6-Secocholestan-6-Al on the Thermotropic and Structural Properties of Mixtures of Phosphatidylethanolamine and Phosphatidylcholine [PDF]

, 2010
Ellen Wachtel, D. Bach, Richard M. Epand, Rachel F. Epand, I.R. Miller   +4 more
openalex   +1 more source

Exploring the Mechanism of Alyteserin‐1c in Gram‐Positive and Gram‐Negative Bacterial Membrane Models Using a Computational Approach

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Alyteserin‐1c hexamer was investigated in biomimetic Gram‐positive and Gram‐negative membrane models using all‐atom molecular dynamics simulations to understand its membrane disruption behavior. The hexamer remained structurally stable in both membrane environments, with hydrophobic inter‐monomer interactions maintaining oligomer integrity while ...
Akshay Sasidharan, Rajasekaran Ramalingam   +1 more
wiley   +1 more source

Glucose may be biotransformed and then react with alcohol, fats, endocannabinoids, or various amino acids to form dopamine or norepinephrine in vivo

Frontiers in Pharmacology
Paul J. Fitzgerald
doaj   +1 more source

Human milk phospholipids across lactation stages and their associations with infant neurodevelopment: a prospective cohort study in China. [PDF]

Front Nutr
Yang S, Guo Q, Zheng T, Yang N, Yang C, Cui M, Li T, Liu X, Lin H, Cheng Q, Li S, Liu P, Wang L.   +12 more
europepmc   +1 more source

The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 6, June 2026.
To define the mechanisms of sensitivity to PP2A inhibitors (PP2Ai), we combined molecular profiling of PP2Ai responses with genome‐wide genetic screens. PP2Ai preferentially target mesenchymal pancreatic ductal adenocarcinoma (PDAC) cells and engage pathways linked to transcriptional elongation, splicing, metabolism, and ER stress response factors ...
Janine Murr, Carolin Schneider, Ningjun Duan, Hazal Köse, Anantharamanan Rajamani, Xueyang He, Jonas Buchloh, Christian Hintze, Atharva Naik, Daniel Goeke, Nicole Rjasanow, Lukas Krauß, Alexandra Nguyen, Sebastian A. Widholz, Christian Schneeweis, Riccardo Trozzo, Felix Orben, Sebastian Mueller, Rupert Öllinger, Juan J Montero, Michael Dudek, Percy Knolle, Bo Kong, Volker Ellenrieder, Constanza Tapia Contreras, Elisabeth Hessmann, Marian Grade, Michael Ghadimi, Christian J. Braun, Roland Rad, Maximillian Reichert, Ulrich Keller, Roland M. Schmid, Paul L. Boutz, Dieter Saur, Matthias Wirth, Oliver H. Krämer, Günter Schneider   +37 more
wiley   +1 more source

Bioartificial Livers Developed From Gene‐Edited Pig Hepatocyte Organoids Improve Amino Acid and Lipid Profiles in the Plasma of Patients With Liver Failure

MedComm, Volume 7, Issue 6, June 2026.
A bioartificial liver (BAL) integrating GGTA1‐knockout porcine hepatocytes and R‐spondin1‐overexpressing endothelial organoids was tested using plasma from patients with acute‐on‐chronic liver failure (ACLF). The BAL system actively modulates amino acid and lipid metabolism, enhances detoxification, partially restores overall metabolic balance, and ...
Yuting He, Yang Deng, Xinglong Zhu, Mengyu Gao, Qin Liu, Wanliu Peng, Yanyan Zhou, Lang Bai, Ji Bao   +8 more
wiley   +1 more source

Phosphatidylethanolamine Improves Postnatal Growth Retardation by Regulating Mucus Secretion of Intestinal Goblet Cells in Piglets [PDF]

Nan Wang, Chengming Wang, Ming Qi, Xingtong Lin, Andong Zha, Bie Tan, Yulong Yin, Jing Wang   +7 more
openalex   +1 more source

ラット小腸平滑筋におけるPhosphatidylethanolamineの水解に関する研究

Studies on enzymatic hydrolysis of phosphatidylethanolamine in rat small intestinal smooth muscle were carried out in comparison with that in the small intestinal mucosa.
西村, 護
core  

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source