Results 161 to 170 of about 31,010 (310)

Advancements in Ambient Ionisation Mass Spectrometry in 2024: An Annual Review

open access: yesAnalytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT The introduction of ambient ionisation mass spectrometry (AIMS) is among the most important developments in analytical chemistry in recent years. Enabling the direct analysis of samples in their native state with neither sample preparation nor chromatographic separation provides chemical characterisation in a matter of seconds.
Alisha Henderson   +2 more
wiley   +1 more source

Emerging Links Between Ferroptosis and Neurodegeneration: Implications for Disease Mechanisms and Nutraceutical Interventions

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
Ferroptosis, a controlled cell death, is driven by iron and characterized by reactive oxygen species and lipid peroxidation. The impact of lipid peroxides, GSH/GPX4, and iron metabolism–targeting small molecule inhibitors is discussed. Nucleic acids, proteins, and phytochemicals are implicated as inhibitors of ferroptosis.
Anwar Ali   +10 more
wiley   +1 more source

A human skin microbiome reference catalog and the skin microbial landscape of plateau adults

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
Understanding the skin microbiome is crucial for elucidating its role in health and disease. However, comprehensive studies on the genetic and functional diversity of the skin microbiome in individuals living in extreme environments remain scarce. This work explores the unique characteristics and functional adaptations of the plateau skin microbiome ...
Yi Liu   +29 more
wiley   +1 more source

Phosphatidylethanolamine Protects Nucleus Pulposus Cells From Oxidative Stress‐Induced Cellular Senescence and Extracellular Matrix Degradation by Promoting Autophagy

open access: yesJOR SPINE, Volume 8, Issue 2, June 2025.
In this study, we utilized LC/MS‐based untargeted metabolomics analysis to examine changes in the metabolite profiles of NP cells under stress conditions. Upon analysis, PE was identified as a differentially abundant metabolite for its decreased content within advanced‐stage NP cells.
Yijun Dong   +9 more
wiley   +1 more source

Phosphatidylethanolamines are the Main Lipid Class Altered in Red Blood Cells from Patients with VPS13A Disease/Chorea-Acanthocytosis. [PDF]

open access: yesMov Disord
Peikert K   +7 more
europepmc   +1 more source

A highly efficient CRISPR‐Cas9‐based gene‐editing system in oat (Avena sativa L.)

open access: yes
Plant Biotechnology Journal, EarlyView.
Mehtab‐Singh   +3 more
wiley   +1 more source

Phosphatidylcholine Ameliorates Palmitic Acid‐Induced Lipotoxicity by Facilitating Endoplasmic Reticulum and Mitochondria Contacts in Intervertebral Disc Degeneration

open access: yesJOR SPINE, Volume 8, Issue 2, June 2025.
The abnormal lipotoxic condition in nucleus pulposus (NP) cells from advanced‐stage intervertebral disc degeneration (IDD) was identified through untargeted LC/MS metabolomics and magnetic resonance spectroscopy. The palmitic acid accumulation resulted in endoplasmic reticulum stress, mitochondrial damage, lipid droplet accumulation, and senescence of ...
Shuangshuang Tu   +6 more
wiley   +1 more source

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