Results 161 to 170 of about 35,571 (360)

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

Dietary Fatty Acids Control the Species of N-Acyl-Phosphatidylethanolamines Synthesized by Therapeutically Modified Bacteria in the Intestinal Tract.

ACS Infectious Diseases, 2018
Noura Sayed Dosoky, Lilu Guo, Zhongyi Chen, Andrew Feigley, S. Davies   +4 more
semanticscholar   +1 more source

Abstract 2311 Two Bridge-like lipid transfer proteins (BLTPs) transport phosphatidylethanolamine at membrane contact sites to facilitate GPI-anchored biogenesis and maintain plasma membrane fluidity [PDF]

Alexandre Toulmay, Suhbhrajit Banerjee, Emma Johnson, William A. Prinz   +3 more
openalex   +1 more source

Enhancing Lipidomics With High‐Resolution Ion Mobility‐Mass Spectrometry

PROTEOMICS, EarlyView.
ABSTRACT Lipids, indispensable yet structurally intricate biomolecules, serve as critical regulators of cellular function and disease progression. Conventional lipidomics, constrained by limited resolution for isomeric and low‐abundance species, has been transformed by ion mobility‐mass spectrometry (IM‐MS).
Gaoyuan Lu, Shuling Xu, Penghsuan Huang, Lingjun Li   +3 more
wiley   +1 more source

High-fat diet feeding differentially affects the development of inflammation in the central nervous system [PDF]

, 2016

core   +1 more source

Symmetrically substituted dichlorophenes inhibit N -acyl-phosphatidylethanolamine phospholipase D [PDF]

, 2020
Geetika Aggarwal, Jonah E. Zarrow, Zahra Mashhadi, Charles R. Flynn, Paige N. Vinson, C. David Weaver, Sean S. Davies   +6 more
openalex   +1 more source

Proteomic and Lipidomic Profiling of Immune Cell‐Derived Subpopulations of Extracellular Vesicles

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study aimed to determine proteomic and lipidomic differences among four EV subpopulations. Large and small EVs
Anna Lischnig, Nasibeh Karimi, Per Larsson, Karin Ekström, Rossella Crescitelli, Anna‐Carin Olin, Cecilia Lässer   +6 more
wiley   +1 more source

Electrochemical oxidation of phosphatidylethanolamines studied by mass spectrometry.

Journal of Mass Spectrometry, 2018
Simone Colombo, Giulia Coliva, A. Kraj, J. Chervet, M. Fedorova, P. Domingues, M. Domingues   +6 more
semanticscholar   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

VIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin   +8 more
wiley   +1 more source