Results 181 to 190 of about 10,710 (280)

Citrate‐Dependent Activation of Acetyl CoA Carboxylase Promotes Renal Lipid Accumulation in a Rat Model of Chronic Kidney Disease

open access: yesActa Physiologica, Volume 242, Issue 5, May 2026.
ABSTRACT Background Abnormal accumulation of lipids within the kidney contributes to the progression of chronic kidney disease, but the underlying metabolic mechanisms remain unclear. Citrate is a central metabolite in cellular energy regulation and is frequently elevated in advanced kidney disease, yet its impact on renal lipid metabolism has not been
Marta Sanz‐Gómez   +8 more
wiley   +1 more source

Lipoprotein Metabolism in the Suckling Rat - Characterization of Plasma and Lymphatic Lipoproteins [PDF]

open access: yes, 1983
Clark, WA   +3 more
core  

Upregulation of sphingomyelin and ABCA8 in response to TDP‐43 pathology in amyotrophic lateral sclerosis brain

open access: yesBrain Pathology, Volume 36, Issue 3, May 2026.
Increases in sphingomyelin in response to TDP‐43 pathology in the disease‐affected motor cortex of amyotrophic lateral sclerosis (ALS) brain. Abstract Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease characterized by the degeneration of motor neurons and the presence of TAR DNA‐binding protein 43 (TDP‐43 ...
Finula I. Isik   +4 more
wiley   +1 more source

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry

open access: yesAngewandte Chemie, Volume 138, Issue 18, 27 April 2026.
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Catherine Zhang   +7 more
wiley   +2 more sources

Linking lipid profile alterations to antibiotic tolerance and natural product synergy in drug-resistant Mycobacterium tuberculosis clinical isolates. [PDF]

open access: yesSci Rep
Zabost A   +10 more
europepmc   +1 more source

The Ti Plasmid‐Encoded VirJ Functions as a Lysyl‐Phosphatidylglycerol Hydrolase in Agrobacterium tumefaciens

open access: yesMolecular Microbiology, Volume 125, Issue 5, Page 426-441, May 2026.
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz   +9 more
wiley   +1 more source

Identification of plasma biomarkers in lipid metabolism for accurate prediction of Alzheimer's disease. [PDF]

open access: yesTransl Psychiatry
Luo X   +6 more
europepmc   +1 more source

Abscisic Acid Induces Triacylglycerol Accumulation and Lipid Remodelling in Chloroplast‐Containing Green Tissues of Lemna minor

open access: yesPlant, Cell &Environment, Volume 49, Issue 5, Page 2464-2479, May 2026.
ABSTRACT Lipid remodelling is a fundamental component of plant responses to environmental stress and development, yet its regulation in fast‐growing aquatic plants remains poorly understood. Here, we investigated how abscisic acid (ABA) regulates triacylglycerol (TAG) accumulation and fatty acid (FA) composition in the duckweed Lemna minor.
Eunbi Kim   +11 more
wiley   +1 more source

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