Results 191 to 200 of about 8,364 (275)

NR4A2-driven metabolic reprogramming in the heart: from adaptive response to maladaptive remodeling. [PDF]

Physiol Genomics
Stujanna EN, Yoshioka J.
europepmc   +1 more source

Mitochondrial membrane remodeling in stress adaptation: Lipid control of organelle quality

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Mitochondria respond to proteotoxic stress through the mitochondrial unfolded protein response, traditionally viewed as a transcriptional program that restores proteostasis by inducing chaperones and proteases. Emerging evidence indicates that mitochondrial membrane remodeling constitutes an additional adaptive component of this response ...
Lena J. Reichert, F.‐Nora Vögtle, Carlotta Peselj   +2 more
wiley   +1 more source

Plasma complex lipids in relation to cortical thickness and brain volumes: results from the population-based Rhineland study. [PDF]

Lipids Health Dis
Landstra EN, Lohner V, Tavares JF, Diers K, Koch A, Breteler MMB.   +5 more
europepmc   +1 more source

Progerin Hinders Autophagy Flux at Its Final Stages in Hutchinson‐Gilford Progeria Syndrome Cells, Preventing Its Own Autophagic Degradation

Aging Cell, Volume 25, Issue 8, August 2026.
We demonstrated that progerin induces the formation of autophagosomes but impairs their maturation and subsequent fusion with lysosomes. Progerin impedes proper autophagy flux, thus preventing its own autophagic degradation. Selinexor treatment improved both autophagosome maturation and autophagosome‐lysosome fusion, which ultimately led to effective ...
Ian García‐Aguirre, Jesús Alejandro Reyes‐Martínez, Juan Unzueta, Francisco Guevara‐Namorado, Solangy Lizcano‐Meneses, Susana Gonzalo, Angel Baldan, Claudia Rangel, Gerardo J. Alanis‐Funes, Francisco Garcia‐Sierra, Kevin Ruiz‐Fajardo, Simon Gormes‐Pinchanski, Susana Castro‐Obregón, Aranza Meza‐Dorantes, Rocio Alejandra Chavez‐Santoscoy, Isabel Arrieta‐Cruz, Paola Tristán‐Aburto, Jonathan J. Magaña, Bulmaro Cisneros   +18 more
wiley   +1 more source

C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato, Giacomo Bettin, Chiara Dalla Torre, Lorenzo Stella, Marta De Zotti   +4 more
wiley   +1 more source

Cold-Induced Lipidomic Remodelling Is Associated With Brown Adipose Tissue Mean Radiodensity in Humans. [PDF]

Diabetes Obes Metab
Zhang Y, Martinez-Tellez B, Kindt A, Drouin N, Harms A, Hankemeier T, Ruiz JR, Jurado-Fasoli L.   +7 more
europepmc   +1 more source

Facultative predation expands the ecological repertoire of <i>Streptomyces</i>. [PDF]

mBio
Yamada K, Koroleva A, Tirkkonen H, Siitonen V, Laughlin M, Moglia A, Matroodi S, Akhgari A, Mazurier G, Niemi J, Metsä-Ketelä M.   +10 more
europepmc   +1 more source

Lipid Composition of Camel Milk and Cow Milk in Xinjiang Province of China Analyzed by Method of Ultra-Performance Liquid Chromatography Quadrupole Time of Flight Mass Spectrometry (UPLC-Q-TOF-MS). [PDF]

Food Sci Anim Resour
Miao J, Wang J.
europepmc   +1 more source

Roles of Metabolomics in Allergic Rhinitis: From Cell to Bedside Investigations. [PDF]

Int J Mol Sci
Saligupta P, Lao-Araya M, Chattipakorn SC, Chattipakorn N, Thonusin C.   +4 more
europepmc   +1 more source

Might modulation of the endocannabinoid system provide a potential dual therapeutic strategy for osteoporosis and depression?

General Psychiatry, Volume 39, Issue 4, August 2026.
Peng Wei, Pianpian Zhao, Zenghui Gu, Mengyuan Yang, David Karasik, Ching‐Lung Cheung, Houfeng Zheng   +6 more
wiley   +1 more source