Results 11 to 20 of about 9,879 (286)

Schisandra lignans ameliorate nonalcoholic steatohepatitis by regulating aberrant metabolism of phosphatidylethanolamines

open access: yesActa Pharmaceutica Sinica B, 2023
Nonalcoholic steatohepatitis (NASH) is a spectrum of chronic liver disease characterized by hepatic lipid metabolism disorder. Recent reports emphasized the contribution of triglyceride and diglyceride accumulation to NASH, while the other lipids ...
Lijuan Xue   +10 more
doaj   +1 more source

Maternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates

open access: yesScientific Reports, 2021
Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters.
Max T. Aung   +8 more
doaj   +1 more source

ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer [PDF]

open access: yesNature Communications, 2012
ATP-binding cassette (ABC) transporters comprise a superfamily of proteins, which actively transport a variety of compounds across cell membranes. Mammalian and most eukaryotic ABC transporters function as exporters, flipping or extruding substrates from the cytoplasmic to the extracellular or lumen side of cell membranes.
Quazi, Faraz   +2 more
openaire   +2 more sources

Lipid metabolism disorders contribute to hepatotoxicity of ICR mice induced by nitrosamines exposure

open access: yesEnvironment International, 2022
Health risks caused by crucial environmental carcinogens N-nitrosamines triggered ubiquitous attention. As the liver exerted vital function through metabolic process, lipid metabolism disorders have been confirmed as potential drivers for toxicological ...
Hu Zhang   +9 more
doaj   +1 more source

Spatial distribution of glycerophospholipids in the ocular lens. [PDF]

open access: yesPLoS ONE, 2011
Knowledge of the spatial distribution of lipids in the intraocular lens is important for understanding the physiology and biochemistry of this unique tissue and for gaining a better insight into the mechanisms underlying diseases of the lens.
Jaroslav Pól   +9 more
doaj   +1 more source

Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis

open access: yesRedox Biology, 2021
Hydroperoxy-eicosatetraenoyl-phosphatidylethanolamine (HpETE-PE) is a ferroptotic cell death signal. HpETE-PE is produced by the 15-Lipoxygenase (15LOX)/Phosphatidylethanolamine Binding Protein-1 (PEBP1) complex or via an Fe-catalyzed non-enzymatic ...
Tamil S. Anthonymuthu   +15 more
doaj   +1 more source

Giant Vesicles Produced with Phosphatidylcholines (PCs) and Phosphatidylethanolamines (PEs) by Water-in-Oil Inverted Emulsions

open access: yesLife, 2021
(1) Background: giant vesicles (GVs) are widely employed as models for studying physicochemical properties of bio-membranes and artificial cell construction due to their similarities to natural cell membranes.
Boying Xu   +3 more
doaj   +1 more source

Increased ω6-Containing Phospholipids and Primary ω6 Oxidation Products in the Brain Tissue of Rats on an ω3-Deficient Diet. [PDF]

open access: yesPLoS ONE, 2016
Polyunsaturated fatty acyl (PUFA) chains in both the ω3 and ω6 series are essential for normal animal brain development, and cannot be interconverted to compensate for a dietary deficiency of one or the other.
Paul H Axelsen   +3 more
doaj   +1 more source

Phosphatidylethanolamine Levels and Regulation of Phosphatidylethanolamine N- Methyltransferase

open access: yesJournal of Biological Chemistry, 1989
The activity of phosphatidylethanolamine (PE) N-methyltransferase in liver microsomes, measured using endogenous microsomal PE as a substrate, was elevated 2-fold in the choline-deficient state. However, methyltransferase activity assayed in the presence of a saturating concentration of phosphatidyl-N-mono-methylethanolamine or microsomal PE was ...
N D, Ridgway, Z, Yao, D E, Vance
openaire   +2 more sources

Home - About - Disclaimer - Privacy