Results 11 to 20 of about 35,571 (360)

N-aldehyde-modified phosphatidylethanolamines generated by lipid peroxidation are robust substrates of N-acyl phosphatidylethanolamine phospholipase D [PDF]

Journal of Lipid Research
N-acyl phosphatidylethanolamine-hydrolyzing phospholipase D (NAPE-PLD) hydrolyzes phosphatidylethanolamines (PEs) where the headgroup nitrogen has been enzymatically modified with acyl chains of four carbons or longer (N-acyl-PEs or NAPEs).
Reza Fadaei, Annie C. Bernstein, Andrew N. Jenkins, Allison G. Pickens, Jonah E. Zarrow, Abdul-Musawwir Alli-Oluwafuyi, Keri A. Tallman, Sean S. Davies   +7 more
doaj   +2 more sources

Lipidomic profiling of the cerebrospinal fluid in moyamoya angiopathy patients [PDF]

Orphanet Journal of Rare Diseases
Background Moyamoya angiopathy (MA) is a rare cerebrovascular disorder which can occur in both children and young adults, characterized by progressive occlusion of the intracranial carotid arteries, leading patients to ischemic and haemorrhagic strokes ...
Antonella Potenza, Gemma Gorla, Tatiana Carrozzini, Giuliana Pollaci, Michele Dei Cas, Francesco Acerbi, Ignazio G. Vetrano, Paolo Ferroli, Isabella Canavero, Rita Paroni, Nicola Rifino, Anna Bersano, Laura Gatti   +12 more
doaj   +2 more sources

Sex‐Associated Metabolites and Incident Stroke, Incident Coronary Heart Disease, Hypertension, and Chronic Kidney Disease in the REGARDS Cohort [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Sex disparities exist in cardiometabolic diseases. Metabolomic profiling offers insight into disease mechanisms, as the metabolome is influenced by environmental and genetic factors. We identified metabolites associated with sex and determined
Catharine A. Couch, Zsuzsanna Ament, Amit Patki, Naruchorn Kijpaisalratana, Varun Bhave, Alana C. Jones, Nicole D. Armstrong, Mary Cushman, W. Taylor Kimberly, M. Ryan Irvin   +9 more
doaj   +2 more sources

Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc ₁ complex function [PDF]

Journal of Biological Chemistry, 2018
Elizabeth Calzada, J. Michael McCaffery, Steven M. Claypool   +2 more
openalex   +3 more sources

Isolevuglandins covalently modify phosphatidylethanolamines in vivo: detection and quantitative analysis of hydroxylactam adducts.

Free Radical Biology & Medicine, 2009
Wei Li, James M. Laird, Liang Lu, S. Roychowdhury, L. Nagy, Rong Zhou, J. Crabb, R. G. Salomon   +7 more
semanticscholar   +2 more sources

Phosphatidylethanolamine Deficiency and Triglyceride Overload in Perilesional Cortex Contribute to Non-Goal-Directed Hyperactivity after Traumatic Brain Injury in Mice

Biomedicines, 2022
Traumatic brain injury (TBI) is often complicated by long-lasting disabilities, including headache, fatigue, insomnia, hyperactivity, and cognitive deficits.
Lisa Hahnefeld, Alexandra Vogel, Robert Gurke, Gerd Geisslinger, Michael K. E. Schäfer, Irmgard Tegeder   +5 more
doaj   +1 more source

Phosphatidylethanolamines Are Associated with Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Adults and Induce Liver Cell Metabolic Perturbations and Hepatic Stellate Cell Activation

International Journal of Molecular Sciences, 2023
Pathogenesis roles of phospholipids (PLs) in nonalcoholic fatty liver disease (NAFLD) remain incompletely understood. This study investigated the role of PLs in the progression of NAFLD among obese individuals via studying the alterations in serum PL ...
Samaa Shama, H. Jang, Xiaokun Wang, Yang Zhang, Nancy Nabil Shahin, T. Motawi, Seongho Kim, S. Gawrieh, Wanqing Liu   +8 more
semanticscholar   +1 more source

PE, or not PE, that is the question: the case of overlooked Lyso-N-acyl-phosphatidylethanolamines.

Rapid Communications in Mass Spectrometry, 2023
RATIONALE Lyso derivatives of N-acyl-1,2-diacyl-glycero-3-phosphoethanolamines (L-NAPEs) are a lipid class mostly expressed in vegetables during stress and tissue damage that is involved in the synthesis of the lipid mediator N-acyl ethanolamines.
G. Ventura, C. Calvano, M. Bianco, A. Castellaneta, I. Losito, T. Cataldi   +5 more
semanticscholar   +1 more source

Exploring preconception signatures of metabolites in mothers with gestational diabetes mellitus using a non-targeted approach

BMC Medicine, 2023
Background Metabolomic changes during pregnancy have been suggested to underlie the etiology of gestational diabetes mellitus (GDM). However, research on metabolites during preconception is lacking.
Ling-Jun Li, Ximeng Wang, Yap Seng Chong, Jerry Kok Yen Chan, Kok Hian Tan, Johan G. Eriksson, Zhongwei Huang, Mohammad L. Rahman, Liang Cui, Cuilin Zhang   +9 more
doaj   +1 more source

Maternal lipidomic signatures in relation to spontaneous preterm birth and large-for-gestational age neonates

Scientific Reports, 2021
Lipidome-wide metabolites may be useful biomarkers of pregnancy outcomes. We sought to characterize maternal lipidomic signatures associated with preterm birth and neonatal anthropometric parameters.
Max T. Aung, Pahriya Ashrap, Deborah J. Watkins, Bhramar Mukherjee, Zaira Rosario, Carmen M. Vélez-Vega, Akram N. Alshawabkeh, José F. Cordero, John D. Meeker   +8 more
doaj   +1 more source