Results 191 to 200 of about 9,879 (286)

Lipid Droplet‐Localized Spindle Apparatus Coiled‐Coil Protein 1 Regulates Lipid Droplet Distribution

Advanced Science, Volume 13, Issue 14, 9 March 2026.
SPDL1‐L, a long isoform of SPDL1, is identified as a bona fide lipid droplet‐associated protein that acts as a dynein adaptor to drive perinuclear clustering of lipid droplets. By linking lipid droplets to the microtubule network, SPDL1‐L extends the function of SPDL1 beyond mitosis and contributes to lipid droplet organization and nuclear remodeling ...
Honggang Su, Huimin Pan, Yaqiang Liu, Wei Wang, Yang Jiao, Yumo Hang, Xiahe Huang, Yong E. Zhang, Yuhang Chen, Mei Ding, Xun Huang   +10 more
wiley   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, Volume 13, Issue 14, 9 March 2026.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Description of <i>Catenibacterium mitsuokai</i> subsp. <i>tridentinum</i> subsp. nov., an anaerobic bacterium isolated from human faeces, and emended description of <i>C. mitsuokai</i>. [PDF]

Int J Syst Evol Microbiol
Ricci L, Selma-Royo M, Golzato D, Servais C, Nabinejad A, Marchi P, Punčochář M, Trenti F, Garcia-Aloy M, Armanini F, Marconi R, Asnicar F, Pinto F, Guella G, Tamburini S, Segata N.   +15 more
europepmc   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, Volume 13, Issue 16, 18 March 2026.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Increasing PFAS concentrations in human serum correlate with elevated blood lipid levels.

Env Sci Adv
Falls AT, Boatman AK, Ryan JP, Solosky AM, Dodds JN, Chappel JR, Fry AN, Kirkwood-Donelson KI, Stapleton HM, Baker ES.   +9 more
europepmc   +1 more source

Plasma lipidomic analysis reveals distinct lipid alterations in patients with pulmonary tuberculosis. [PDF]

Eur J Med Res
Zhang C, Cai M, Cai H, Chen X.
europepmc   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Lipidomic Comparison of Detergent-Soluble and Detergent-Resistant Lipid Domains Isolated From Rat Cerebellum and the Effect of Hypoxia-Ischemia Using UPLC-HDMS^E. [PDF]

J Mass Spectrom
Krug SA, He M, Tang N, Bearer C, Kane MA.   +4 more
europepmc   +1 more source

Efficient Preservation of Perishable Fruits by Erasable Metal‐Organic Frameworks

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This study presents an erasable Pickering emulsion‐based coating stabilized by metal‐organic frameworks. This washable coating significantly extends fruit shelf life by scavenging ethylene and inhibiting foodborne pathogens, offering a sustainable solution for postharvest.
Liying Yang, Jia Kong, Haoran Bai, Xiaojie Wu, Douxin Xiao, Ming Du, Peng Yang, Alideertu Dong   +7 more
wiley   +1 more source

A Nonketotic Hyperglycinemia Mouse Shows Wide-Ranging Biochemical Consequences of Elevated Glycine, Reduced Folate One-Carbon Charging, and Serine Deficiency. [PDF]

J Inherit Metab Dis
Swanson MA, Jiang H, Kolora LD, Molino R, Reisdorph R, Michel CR, Doenges KA, Leung KY, Lin X, Wong F, Lancaster S, Michael B, Snyder M, Hock DH, Stroud DA, Wood T, Binard R, Anderson-Lehman L, Christians U, Arning E, Friederich MW, Van Hove RA, MacLean KN, Greene NDE, Van Hove JLK.   +24 more
europepmc   +1 more source