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Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source
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Glycosyl Phosphatidylinositol Anchor

Nephron Experimental Nephrology, 1998
Recently, we and others demonstrated the unique potential for glycosyl phosphatidylinositol (GPI) anchored proteins to transfer from one cell membrane to another in a process we termed ‘painting’. The GPI-anchored proteins were shown to transfer intact and functional.
D L, Kooyman, G W, Byrne, J S, Logan
openaire   +2 more sources

Phosphatidylinositol 3‐kinase

BioEssays, 1994
AbstractCurrently, a central question in biology is how signals from the cell surface modulate intracellular processes. In recent years phosphoinositides have been shown to play a key role in signal transduction. Two phosphoinositide pathways have been characterized, to date.
R, Kapeller, L C, Cantley
openaire   +2 more sources

Phosphatidylinositol signalling reactions

Seminars in Cell & Developmental Biology, 1998
Phosphatidylinositols are important in intracellular signaling. In response to extracellular signals, these molecules undergo rapid turnover and generate second messengers including diacylglycerol, inositol 1,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate (PtdIns 3,4P2) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3).
X, Zhang, P W, Majerus
openaire   +2 more sources

Trafficking of phosphatidylinositol by phosphatidylinositol transfer proteins

Biochemical Society Symposia, 2007
PtdIns is synthesized at the endoplasmic reticulum and its intracellular distribution to other organelles can be facilitated by lipid transfer proteins [PITPs (phosphatidylinositol transfer proteins)]. In this review, I summarize the current understanding of how PITPs are regulated by phosphorylation, how can they dock to membranes to exchange their ...
openaire   +2 more sources

Modulation of phosphatidylinositol turnover by liposomes containing phosphatidylinositol

1987
Publisher Summary This chapter discusses the methods for preparing liposomes for coating (opsonizing) the liposomes with immunoglobulin M (IgM) antibodies and complement or opsonizing with concanavalin A (Con A) to promote phagocytosis and resulting increased phosphatidylinositol (PI) turnover, for obtaining and culturing mouse peritoneal macrophages,
N M, Wassef, C R, Alving
openaire   +2 more sources

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