Results 301 to 310 of about 387,101 (335)

Glycosyl Phosphatidylinositol Anchor

Nephron Experimental Nephrology, 1998
Recently, we and others demonstrated the unique potential for glycosyl phosphatidylinositol (GPI) anchored proteins to transfer from one cell membrane to another in a process we termed ‘painting’. The GPI-anchored proteins were shown to transfer intact and functional.
D L, Kooyman, G W, Byrne, J S, Logan
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Phosphatidylinositol 3‐kinase

BioEssays, 1994
AbstractCurrently, a central question in biology is how signals from the cell surface modulate intracellular processes. In recent years phosphoinositides have been shown to play a key role in signal transduction. Two phosphoinositide pathways have been characterized, to date.
R, Kapeller, L C, Cantley
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Phosphatidylinositol signalling reactions

Seminars in Cell & Developmental Biology, 1998
Phosphatidylinositols are important in intracellular signaling. In response to extracellular signals, these molecules undergo rapid turnover and generate second messengers including diacylglycerol, inositol 1,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate (PtdIns 3,4P2) and phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3).
X, Zhang, P W, Majerus
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Trafficking of phosphatidylinositol by phosphatidylinositol transfer proteins

Biochemical Society Symposia, 2007
PtdIns is synthesized at the endoplasmic reticulum and its intracellular distribution to other organelles can be facilitated by lipid transfer proteins [PITPs (phosphatidylinositol transfer proteins)]. In this review, I summarize the current understanding of how PITPs are regulated by phosphorylation, how can they dock to membranes to exchange their ...
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Modulation of phosphatidylinositol turnover by liposomes containing phosphatidylinositol

1987
Publisher Summary This chapter discusses the methods for preparing liposomes for coating (opsonizing) the liposomes with immunoglobulin M (IgM) antibodies and complement or opsonizing with concanavalin A (Con A) to promote phagocytosis and resulting increased phosphatidylinositol (PI) turnover, for obtaining and culturing mouse peritoneal macrophages,
N M, Wassef, C R, Alving
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Phosphatidylinositol 4-kinases, phosphatidylinositol 4-phosphate and cancer

Cancer Letters, 2012
This article focuses on the emerging roles for phosphatidylinositol 4-phosphate and the phosphatidylinositol 4-kinases in cancer. Phosphatidylinositol 4-phosphate is a common substrate for both the phosphatidylinositol 3-kinase and phospholipase C pathways, and has been implicated in the membrane targeting of proteins such as Girdin/GIV and OSBP ...
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Phosphatidylinositol phosphate kinases.

Journal of endocrinological investigation, 2004
Phosphatidylinositol 4,5-bisphosphate is a multi-functional lipid, whose proposed functions now number more than twenty, covering many aspects of cell biology in several different subcellular compartments. The enzymes primarily responsible for synthesizing this lipid, the Type I phosphatidylinositol 4-phosphate 5-kinases, are therefore a tightly ...
Giudici, ML, Hinchliffe, KA, Irvine, RF
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Oncogenes and Phosphatidylinositol Turnover

Annals of the New York Academy of Sciences, 1986
Products of phosphatidylinositol turnover have recently been implicated as regulators of cell growth and differentiation. Transformation of cells in culture by infection with certain viruses (Rous sarcoma virus, Kirsten sarcoma virus, and polyoma virus) or by transfection with the oncogenes carried by these viruses affect the steady-state level of ...
L C, Cantley, M, Whitman, S, Chahwala, L, Fleischman, D R, Kaplan, B S, Schaffhausen, T M, Roberts   +6 more
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