Results 311 to 320 of about 363,126 (392)

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Phosphatidylethanolamines are the Main Lipid Class Altered in Red Blood Cells from Patients with VPS13A Disease/Chorea‐Acanthocytosis

open access: yesMovement Disorders, Volume 40, Issue 3, Page 544-549, March 2025.
VPS13A disease has become paradigmatic for a new pathophysiological concept in neurodegeneration: disturbed bulk lipid transfer at membrane contact sites. VPS13A is a bridge‐like lipid transfer protein. Loss of VPS13A function leads to deformed red blood cells (RBCs), acanthocytes.
Kevin Peikert   +7 more
wiley   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi   +4 more
wiley   +1 more source

Exploring lipidome mediated inflammatory pathways in acute pancreatitis using mendelian randomization. [PDF]

open access: yesSci Rep
Liu W   +9 more
europepmc   +1 more source

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