Results 281 to 290 of about 19,012 (341)

Unveiling Interactions between Self-Assembling Peptides and Neuronal Membranes. [PDF]

Langmuir
Fontana F, Donato AC, Malik A, Gelain F.
europepmc   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

Modern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li, YiNing Zheng, HuiJun Geng, Lu Deng   +3 more
wiley   +1 more source

Structure of the human TSC:WIPI3 lysosomal recruitment complex. [PDF]

Sci Adv
Bayly-Jones C, Lupton CJ, D'Andrea L, Chang YG, Jones GD, Steele JR, Venugopal H, Schittenhelm RB, Halls ML, Ellisdon AM.   +9 more
europepmc   +1 more source

Phosphatidylinositol 4 Phosphate Regulates Targeting of Clathrin Adaptor AP-1 Complexes to the Golgi

, 2003
Ying Jie Wang, Jing Wang, Hui Sun, Manuel Martínez, Yu Xiao Sun, Eric Macia, Tomas Kirchhausen, Joseph Albanesi, Michael G. Roth, Helen L. Yin   +9 more
openalex   +1 more source

Defining short linear motif binding determinants by phage display‐based deep mutational scanning

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Deep mutational scanning (DMS) has emerged as a powerful approach for evaluating the effects of mutations on binding or function. Here, we developed a DMS by phage display protocol to define the specificity determinants of short linear motifs (SLiMs) binding to peptide‐binding domains.
Caroline Benz, Lars Maassen, Leandro Simonetti, Filip Mihalic, Richard Lindqvist, Ifigenia Tsitsa, Aimiliani Konstantinou, Per Jemth, Anna K. Överby, Norman E. Davey, Ylva Ivarsson   +10 more
wiley   +1 more source

Inhibiting inositol transport disrupts metabolite profiles and mimics heat stress in a model cnidarian-Symbiodiniaceae symbiosis. [PDF]

Commun Biol
Turner LD, Raina JB, Kuzhiumparambil U, Songsomboom K, Matthews JL.   +4 more
europepmc   +1 more source

VCP Promotes Cholangiocarcinoma Development by Mediating BAP1 Ubiquitination‐Dependent Degradation

Cancer Science, Volume 116, Issue 6, Page 1579-1591, June 2025.
It demonstrates the tumor‐suppressive roles of BAP1 in CCA: BAP1 significantly inhibits CCA cell proliferation and tumor progression. It identifies VCP as a key upstream regulator mediating BAP1 homeostasis: VCP binds to BAP1 and promotes the latter's ubiquitination degradation via the ubiquitin‐proteasome pathway.
Peiying Zhang, Xiangning Liu, Yue Liu, Hongdao Zhu, Churun Zheng, Qi Ling, Fangjie Yan, Qiaojun He, Hong Zhu, Tao Yuan, Bo Yang   +10 more
wiley   +1 more source

Nonvesicular cholesterol transport in physiology. [PDF]

J Clin Invest
Ferrari A, Tontonoz P.
europepmc   +1 more source

Global identification of key genes for pollen germination in rice through high‐throughput screening and gene editing

Journal of Integrative Plant Biology, Volume 67, Issue 6, Page 1665-1684, June 2025.
A systematic examination of 107 T‐DNA insertional lines targeting 105 genes preferentially expressed in late pollen development identified 42 lines exhibiting significant deviations from expected Mendelian segregation ratios, suggesting a potential involvement in pollen viability and germination.
Eui‐Jung Kim, Woo‐Jong Hong, Yu‐Jin Kim, Eun Young Kim, Sang Dae Yun, Sunok Moon, Su‐Kyoung Lee, Soon Ki Park, Ki‐Hong Jung   +8 more
wiley   +1 more source

The Role of PHLDA3 in Cancer Progression and Its Potential as a Therapeutic Target. [PDF]

Cancers (Basel)
Kamel WA, Krishnaraj J, Ohki R.
europepmc   +1 more source