Results 101 to 110 of about 133,958 (282)

In vitro approach to the study of chronic exposure to low doses of x-rays [PDF]

, 2011
El presente trabajo fue realizado con el fin de estudiar el efecto de dosis bajas y repetidas de radiación sobre dos líneas celulares de la misma especie. Se desarrolló un modelo in vitro para evitar la influencia de los factores de confusión que afectan
Peral Garcia, Pilar, Ponzinibbio, Maria Virginia, Seoane, Analia Isabel   +2 more
core   +1 more source

How Well Can You Tailor the Charge of Lipid Vesicles? [PDF]

, 2019
Knowledge and control of surface charge or potential is important for tailoring colloidal interactions. In this work, we compare widely used zeta potential (ζ) measurements of charged lipid vesicle surface potential to direct measurements using the ...
Docto, D, Gilbile, D, Kingi, DT, Kuhl, TL, Kurniawan, J, Monahan, D, Tang, A   +6 more
core   +2 more sources

Altered brain lipid composition in cyclooxygenase-2 knockout mouse

Journal of Lipid Research, 2007
Cyclooxygenase (COX)-2 plays an important role in brain arachidonic acid (20:4n-6) metabolism, and its expression is upregulated in animal models of neuroinflammation and excitotoxicity. Our hypothesis was that brain lipid composition would be altered in
Kaizong Ma, Robert Langenbach, Stanley I. Rapoport, Mireille Basselin   +3 more
doaj   +1 more source

Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines [PDF]

, 2017
Rac1 GTPase has long been recognized as a critical regulatory protein in different cellular and molecular processes involved in cancer progression, including acute myeloid leukemia.
Cabrera, Maia Diana Eliana, Cardama, Georgina Alexandra, Davio, Carlos Alberto, Echeverría, Emiliana Beatriz, Fernandez, Natalia Cristina, González, Nazareno, Lorenzano Menna, Pablo, Remes Lenicov, Federico   +7 more
core   +2 more sources

TAM receptors, Phosphatidylserine, inflammation, and Cancer

Cell Communication and Signaling, 2019
The numerous and diverse biological roles of Phosphatidylserine (PtdSer) are featured in this special issue. This review will focus on PtdSer as a cofactor required for stimulating TYRO3, AXL and MERTK – comprising the TAM family of receptor tyrosine ...
T. Burstyn-Cohen, A. Maimon
semanticscholar   +1 more source

Engineered Fluorescent Variants of Lactadherin C2 Domain for Phosphatidylserine Detection in Flow Cytometry

Biomolecules
Phosphatidylserine (PS) is an essential phospholipid and an emerging biomarker involved in key biological processes. While annexin V (axV) is the most widely used tool for PS detection, its calcium-dependent binding and other limitations have spurred ...
Ekaterina Koltsova, Albina Avilova, Elena Nikolaeva, Nikita Kolchin, Kirill Butov   +4 more
doaj   +1 more source

Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-antibodies [PDF]

, 2016
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and ...
Contrufo, Geraldine, Espasandin, Yesica Romina, García, Alejandro Jorge, Glembotsky, Ana Claudia, Goette, Nora Paula, Grodzielski, Matías, Heller, Paula Graciela, Lev, Paola Roxana, Marta, Rosana Fernanda, Molinas, Felisa Concepción, Pierdominici, Marta S., Riveros, Dardo Alberto   +11 more
core   +1 more source

Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Phospholipids in the plasma membrane are scrambled between the two leaflets by TMEM16 proteins. Some TMEM16 family members are also present in intracellular membranes, but whether they scramble phospholipids inside cells has not been ...
Takuma Tsuji, Jinglei Cheng, Tsuyako Tatematsu, A. Ebata, Hiroki Kamikawa, Akikazu Fujita, Sayuri Gyobu, Katsumori Segawa, H. Arai, T. Taguchi, S. Nagata, T. Fujimoto   +11 more
semanticscholar   +1 more source

Sweet Shield: Enhancing Oral Health with Bioactive HETAFU Candies in Adults – A Dose-Dependent Study

Journal of Pharmacy and Bioallied Sciences
Functional foods incorporating probiotics, essential oils, and DHA, PhosphatidylSerine have been explored as innovative approaches to improving oral health.
Sowjanya Lakkoju, Deepika Bolisetty, Ranjith Kumar   +2 more
doaj   +1 more source

Cardiac Specific Overexpression of Mitochondrial Omi/HtrA2 Induces Myocardial Apoptosis and Cardiac Dysfunction. [PDF]

, 2016
Myocardial apoptosis is a significant problem underlying ischemic heart disease. We previously reported significantly elevated expression of cytoplasmic Omi/HtrA2, triggers cardiomyocytes apoptosis.
Jiao, Kun, Lau, Wayne Bond, Liu, Huirong, Liu, Xin, Ma, Lu, Ma, Xinliang, Shang, Jianyu, Wang, Ke, Wang, Wen, Wang, Xiaoliang, Yuan, Yuexing, Zuo, Lin   +11 more
core   +2 more sources