Results 61 to 70 of about 113,870 (234)

Tim-4 in Health and Disease: Friend or Foe?

Frontiers in Immunology, 2020
T-cell immunoglobulin and mucin domain containing 4 (Tim-4) is a phosphatidylserine receptor and is selectively expressed on antigen presenting cells. Recently, Tim-4 was reported to be expressed on iNKT cells, B1 cells, and tumor cells, suggesting it ...
Wen Liu, Liyun Xu, Liyun Xu, Xiaohong Liang, Xiaojun Liu, Yangbing Zhao, Yangbing Zhao, Chunhong Ma, Lifen Gao   +8 more
doaj   +1 more source

Exosomes promote pre-metastatic niche formation in ovarian cancer. [PDF]

, 2019
Ovarian cancer is one of the most common gynecological malignancies. Upon initial diagnosis, the majority of patients present with widespread metastatic growth within the peritoneal cavity. This metastatic growth occurs in stages, with the formation of a
Dean, Dylan C, Duan, Zhenfeng, Feng, Wenlong, Hornicek, Francis J, Shi, Huirong   +4 more
core   +2 more sources

Breakdown of Phospholipid Asymmetry Triggers ADAM17-Mediated Rescue Events in Cells Undergoing Apoptosis

Membranes, 2023
ADAM17, a prominent member of the “Disintegrin and Metalloproteinase” (ADAM) family, controls vital cellular functions through the cleavage of transmembrane substrates, including epidermal growth factor receptor (EGFR) ligands such as transforming growth
Maria Sperrhacke, Sinje Leitzke, Björn Ahrens, Karina Reiss   +3 more
doaj   +1 more source

Helicobacter pylori cholesterol-α-glucosyltransferase manipulates cholesterol for bacterial adherence to gastric epithelial cells

Virulence, 2021
Helicobacter pylori infection is associated with several gastrointestinal diseases, including gastritis, peptic ulcers, and gastric cancer. Infection of cells with H.
Chung-Yao Hsu, Jia-Yin Yeh, Chun-Ya Chen, Hui-Yu Wu, Meng-Hsuan Chiang, Chia-Lin Wu, Hwai-Jeng Lin, Cheng-Hsun Chiu, Chih-Ho Lai   +8 more
doaj   +1 more source

Signal integration by lipid-mediated spatial cross talk between Ras nanoclusters [PDF]

, 2013
Lipid-anchored Ras GTPases form transient, spatially segregated nanoclusters on the plasma membrane that are essential for high-fidelity signal transmission. The lipid composition of Ras nanoclusters however has not previously been investigated.
Abankwa, Abankwa, Andresen, Ariotti, Baumgart, Brown, Brown, Casey, Cho, Deschout, Diggle, Dougherty, Epand, Garcia, Garg, Ghosh, Goldenberg, Gorfe, Gowrishankar, Grande-Garcia, Gutierrez, Hammond, Hancock, Hancock, Hancock, Hancock, Hill, Hong Liang, Jaumot, John F. Hancock, Kale, Kalwa, Kay, Kholodenko, Kiselev, Kiselev, Lee, Miao, Mor, Murakoshi, Nicholas Ariotti, Plowman, Plowman, Prior, Prior, Prior, Prior, Robert G. Parton, Rotblat, Roy, Schroeder, Sharma, Tian, Tian, Travis Rodkey, Treeck, van der Hoeven, van Rheenen, Veatch, Veatch, Voice, Yan, Yeung, Yong Zhou, Zeniou-Meyer, Zhou   +65 more
core   +1 more source

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source

TheDrosophilachemokine-like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons [PDF]

, 2022
Hui Ji, Bei Wang, Yifan Shen, David Labib, Joyce Lei, Xinchen Chen, Maria L. Sapar, Ana Boulanger, Jean‐Maurice Dura, Chun Han   +9 more
openalex   +1 more source

Contribution of the precursors and interplay of the pathways in the phospholipid metabolism of the malaria parasite

Journal of Lipid Research, 2018
The malaria parasite, Plasmodium falciparum, develops and multiplies in the human erythrocyte. It needs to synthesize considerable amounts of phospholipids (PLs), principally phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylserine
Sharon Wein, Salma Ghezal, Corinne Buré, Marjorie Maynadier, Christian Périgaud, Henri J. Vial, Isabelle Lefebvre-Tournier, Kai Wengelnik, Rachel Cerdan   +8 more
doaj   +1 more source

Platelet senescence and phosphatidylserine exposure [PDF]

Transfusion, 2010
BACKGROUND: The exposure of phosphatidylserine occurs during platelet (PLT) activation and during in vitro storage. Phosphatidylserine exposure also occurs during apoptosis after the release of mitochondrial cytochrome c. We have examined the role of cytochrome c release, mitochondrial membrane potential (ΔΨm), and cyclophilin D (CypD) in ...
Swapan Kumar, Dasgupta, Eduardo Rios, Argaiz, Jose Emmanel Chedid, Mercado, Hector Omar Elizondo, Maul, Jorge, Garza, Ana Bety, Enriquez, Hanan, Abdel-Monem, Anthony, Prakasam, Michael, Andreeff, Perumal, Thiagarajan   +9 more
openaire   +2 more sources

Annexin V FITC conjugated as a radiation toxicity indicator in lymphocytes following radiation overexposure in radiotherapy programs

Advanced Biomedical Research, 2015
Background: Following human radiation exposure in hospital or accidents, dose assessments are of prime importance in radiation accidents. These issues are of continuing importance with respect to socioeconomic policy relating to the industrial and ...
Mohammad Bagher Tavakoli, Majid Kheirollahi, Ali Kiani, Mohammad Kazemi, Shaghayegh Haghjooy Javanmard, Leili Mohebat   +5 more
doaj   +1 more source